DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp305a1 and CYP706A4

DIOPT Version :9

Sequence 1:	NP_649151.1	Gene:	Cyp305a1 / 40161	FlyBaseID:	FBgn0036910	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_192967.1	Gene:	CYP706A4 / 826839	AraportID:	AT4G12300	Length:	516	Species:	Arabidopsis thaliana

Alignment Length:	523	Identity:	133/523 - (25%)
Similarity:	223/523 - (42%)	Gaps:	72/523 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 AILIGFVIYSLI--SSARRPK-NFPPGPRFVPWLGNTLQFRKEASAVGGQHILFERWAKDFRSDL 70
            ||:|...::|::  ...|.|: :.|||||.:|.:|| |.|...     ..|..|...|:. ...:
plant    19 AIVILTTVFSILWYIFKRSPQPSLPPGPRGLPIVGN-LPFLDP-----DLHTYFANLAQS-HGPI 76

  Fly    71 VGLKLGREYVVV----ALGHEMVKEVQLQEVFEGRPDNFFLRLRTMGTRKGITCTDGQLWYEHRH 131
            ..|.||.:..:|    :|..|::|:..:.  |..|......|..|.|....:....|..|.:.|.
plant    77 FKLNLGSKLTIVVNSPSLAREILKDQDIN--FSNRDVPLTGRAATYGGIDIVWTPYGAEWRQLRK 139

  Fly   132 FAMKQMRNVGYGRSQMEHHIELEAEELLGQLERT--------EEQPIEPVTWLAQSVLNVLWCLI 188
            ..:.::    ..|..::...||..:|:   .|||        ::.|::....|..:::|:...::
plant   140 ICVLKL----LSRKTLDSFYELRRKEV---RERTRYLYEQGRKQSPVKVGDQLFLTMMNLTMNML 197

  Fly   189 AGKRIARQE--------DGTLRRLLDLMNRRSKLFDICGGLLAQFPWLRHVAPDRTGYNLIQQLN 245
            .|..:..:|        .|.:..:..|:: ...:.|.       ||||...  |..|  |::::.
plant   198 WGGSVKAEEMESVGTEFKGVISEITRLLS-EPNVSDF-------FPWLARF--DLQG--LVKRMG 250

  Fly   246 T---ELYGFFMDTIEEHRRQLAKDPSPAESDLIYAYLQEMKDRSAGGE-SSTFNETQLVMTILDF 306
            .   ||.......||:.:....:|....:..|  .||.::||:....| ..|.|..:.::|  |.
plant   251 VCARELDAVLDRAIEQMKPLRGRDDDEVKDFL--QYLMKLKDQEGDSEVPITINHVKALLT--DM 311

  Fly   307 FIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQ 371
            .:.|:.|::|||..|:..|...|::.::...::...|...:.....|::|   ..|:.|.:.|..
plant   312 VVGGTDTSTNTIEFAMAELMSNPELIKRAQEELDEVVGKDNIVEESHITR---LPYILAIMKETL 373

  Fly   372 RFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSAGKCFK 436
            |.....|:..|.|....|.:|||.|||:..|.:::.|:..|...|::|.|||||||:|:....|.
plant   374 RLHPTLPLLVPHRPAENTVVGGYTIPKDTKIFVNVWSIQRDPNVWENPTEFRPERFLDNNSCDFT 438

  Fly   437 D---EYFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAG------ESPSMVLLPGITLT 492
            .   .|| |||.|||.|.|.|||...:...|..::..|...:|.|      |...:||...|.|.
plant   439 GANYSYF-PFGSGRRICAGVALAERMVLYTLATLLHSFDWKIPEGHVLDLKEKFGIVLKLKIPLV 502

  Fly   493 PKP 495
            ..|
plant   503 ALP 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	p450	30..500	CDD:278495	127/499 (25%)
CYP706A4	NP_192967.1	p450	17..512	CDD:386267	133/523 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000