DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp305a1 and CYP71B5

DIOPT Version :9

Sequence 1:	NP_649151.1	Gene:	Cyp305a1 / 40161	FlyBaseID:	FBgn0036910	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_190896.1	Gene:	CYP71B5 / 824495	AraportID:	AT3G53280	Length:	498	Species:	Arabidopsis thaliana

Alignment Length:	546	Identity:	131/546 - (23%)
Similarity:	219/546 - (40%)	Gaps:	110/546 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 IFLCAILIGFVIYSLISSAR---RPKNFPPGPRFVPWLGNTLQFRKEASAVGGQHILFERWAKDF 66
            ||||.:|:  :..|||...:   .....||||:.:|.:||..||        |:.:     .|..
plant     3 IFLCFLLL--LPLSLIFLKKLLPSKGKLPPGPKGLPIIGNLHQF--------GRFL-----HKSL 52

  Fly    67 RSDLVGLKLGREYVVVALGHEMVKEVQL-------QEVFEGRPDNFFLRLRTMGTRKGITCTD-- 122
            .      |:.:||..|.|.|..|..|.:       :||.:........|.:|:|:  |:...:
plant    53 H------KISQEYGPVMLLHFGVVPVIIVSSKEGAEEVLKTHDLETCSRPKTVGS--GLFTYNFK 109

  Fly   123 -------GQLWYEHRH------FAMKQMRNVGYGRSQMEHHIELEAEELLGQLERTE-EQPIEPV 173
                   |:.|.|.|.      |:.|::::..|.|       |.|::.|:.::.::. |.|...|
plant   110 DIGFAPYGENWREMRKIAVSELFSQKKLKSFRYIR-------EDESQLLVRKVSKSALETPTSSV 167

  Fly   174 TWLAQSVLNVLWCLIAGKRIARQEDG----------TLRRLLDLMNRRSKLFDICGGLLAQFPWL 228
            .      |..:....|...|.|...|          |:..|  ::...:.|..:.........|:
plant   168 N------LRKVIFTFAASIICRLSFGQNFCDFVDMETVEEL--VLESETNLGSLAFADFLPAGWI 224

  Fly   229 RHVAPDRTG--YNLIQQLNTELYGFFMDTIEEHRRQLAKDPSPAESDLIYAYLQEM-KDRSAGGE 290
                .||..  ::.:.:..::|..||...|::|   |........||:|...|..: |....|..
plant   225 ----IDRISGQHSTVMKAFSKLTNFFELVIDDH---LKSGKIEDHSDIISVMLDMINKPTEVGSY 282

  Fly   291 SSTFNETQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLS 355
            ..|.:..:.:|:  |.|:||....|.|:...:..|:..|.|..||..::.|::.       |:..
plant   283 KVTDDHLKGLMS--DVFLAGVNAGSITMIWTMTELSRHPRVMRKLQEEIRAALG-------PNKE 338

  Fly   356 R-----REAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEH 415
            :     .|..:|:...|.|..|.....|:..||..:....:.||.||||..|.|:..::..|.::
plant   339 KITEEDLEKVEYLKMVIEEAFRLHPPAPLLLPRLTMSDINIQGYSIPKNTMIQINTYTIGRDPKN 403

  Fly   416 WKDPLEFRPERFIDSAGKCFKDEYF--MPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAG 478
            |..|.||.||||:|:..: :|.::|  :|||.|||.|.|.|.....:...|:.::..|...||.|
plant   404 WTKPDEFIPERFVDNPIE-YKGQHFELLPFGAGRRVCPGMATGITIVELGLLSLLYFFDWSLPNG 467

  Fly   479 ---------ESPSMVLLPGITLTPKP 495
                     |..:.|:...::|...|
plant   468 MTTKDIDMEEDGAFVIAKKVSLELVP 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	p450	30..500	CDD:278495	123/518 (24%)
CYP71B5	NP_190896.1	CYP71-like	58..489	CDD:410695	109/464 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000