DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp305a1 and CYP71B3

DIOPT Version :9

Sequence 1:	NP_649151.1	Gene:	Cyp305a1 / 40161	FlyBaseID:	FBgn0036910	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_189253.1	Gene:	CYP71B3 / 822223	AraportID:	AT3G26220	Length:	501	Species:	Arabidopsis thaliana

Alignment Length:	503	Identity:	117/503 - (23%)
Similarity:	208/503 - (41%)	Gaps:	69/503 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSALI--FLCAILIGFVIYSLISSARRPKNFPPGPRFVPWLGNTLQFRKEASAVGGQHILFERWA 63
            ||.|:  |...:::..:.......::|  |.||.|..:|.:||..|.|.          ||.|..
plant     1 MSILLYFFFLPVILSLIFMKKFKDSKR--NLPPSPPKLPIIGNLHQLRG----------LFHRCL 53

  Fly    64 KDF---RSDLVGLKLGREYVVVALGHEMVKEVQLQEVFE--GRP-DNFFLRLRTMGTRKGITCTD 122
            .|.   ...::.|:||...:||....|..:||......|  .|| .|...:....|  |.|....
plant    54 HDLSKKHGPVLLLRLGFIDMVVISSKEAAEEVLKVHDLECCTRPKTNASSKFSRDG--KDIAFAP 116

  Fly   123 -GQLWYEHR------HFAMKQMRNVGYGRSQMEHHIELEAEELLGQLERTEEQPIEPVTWLAQSV 180
             |::..|.|      .|:.:::|:..|.|       |.|.:.::.:|:.:.::  :....|:|::
plant   117 YGEVSRELRKLSLINFFSTQKVRSFRYIR-------EEENDLMVKKLKESAKK--KNTVDLSQTL 172

  Fly   181 LNVLWCLI----AGKRIARQEDGTLRRLLDLMNRRSKLFDICGGLLAQ--FP----WLRHVAPDR 235
            ..::..:|    .|:|:.:.:.....::.:||....|:    |.|.:.  ||    |.......|
plant   173 FYLVGSIIFRATFGQRLDQNKHVNKEKIEELMFEVQKV----GSLSSSDIFPAGVGWFMDFVSGR 233

  Fly   236 TGYNLIQQLNTELYGFFMDTIEEHRRQLAKDPSPAESDLIYAYLQEMKDRSAGGESSTFNETQLV 300
              :..:.::..|:.......|:.|.:......:....|:|.:.|:.:. :....||.......|.
plant   234 --HKTLHKVFVEVDTLLNHVIDGHLKNPEDKTNQDRPDIIDSILETIY-KQEQDESFKLTIDHLK 295

  Fly   301 MTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFD---Y 362
            ..|.:.::||..|::.|:..|:..|...|.|.:|...::...:.....:..    ..|..|   |
plant   296 GIIQNIYLAGVDTSAITMIWAMAELVKNPRVMKKAQEEIRTCIGIKQKERI----EEEDVDKLQY 356

  Fly   363 MDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERF 427
            :...|.|..|.....|:..||..:...|:.|||||:...:|::..|:..:.|.|::|.||.||||
plant   357 LKLVIKETLRLHPPAPLLLPRETMADIKIQGYDIPRKTILLVNAWSIGRNPELWENPEEFNPERF 421

  Fly   428 IDS----AGKCFKDEYFMPFGMGRRRCLGDALARACIFSFLVRIVQHF 471
            ||.    .|..|:   .:|||.||:.|.|.|...|.:...|:.::.:|
plant   422 IDCPMDYKGNSFE---MLPFGSGRKICPGIAFGIATVELGLLNLLYYF 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	p450	30..500	CDD:278495	111/472 (24%)
CYP71B3	NP_189253.1	p450	1..500	CDD:386267	117/503 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000