DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp305a1 and CYP71B20

DIOPT Version :9

Sequence 1:	NP_649151.1	Gene:	Cyp305a1 / 40161	FlyBaseID:	FBgn0036910	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_189249.1	Gene:	CYP71B20 / 822219	AraportID:	AT3G26180	Length:	502	Species:	Arabidopsis thaliana

Alignment Length:	562	Identity:	140/562 - (24%)
Similarity:	225/562 - (40%)	Gaps:	126/562 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ALIFLCAILIGFVIYSLISSARRPK----NFPPGPRFVPWLGNTLQFRKEASAVGGQHILFERWA 63
            |:.|||..||  .:.|||..|::.|    |.||.|...|.:||..|. .|......|| |.||:
plant     2 AISFLCFCLI--TLASLIFFAKKIKHLKWNLPPSPPKFPVIGNLHQI-GELPHRSLQH-LAERY- 61

  Fly    64 KDFRSDLVGLKLGREYVVVALGHEMVKEVQLQEVFE--GRPDNFFLRLRTMGTR------KGITC 120
                ..::.|..|...|.|....|..:||......:  .||       :.:|||      |.:..
plant    62 ----GPVMLLHFGFVPVTVVSSREAAEEVLRTHDLDCCSRP-------KLVGTRLLSRNFKDVCF 115

  Fly   121 TD-GQLWYEHRHFAMKQ---MRNVGYGRSQMEHHI-ELEAEELLGQLERT--EEQPIE---PVTW 175
            |. |..|...|.||:::   ::.|     |...|| |.|...|:.||..:  ...|::   .:.|
plant   116 TPYGNEWKARRKFALRELFCLKKV-----QSFRHIREEECNFLVKQLSESAVNRSPVDLSKSLFW 175

  Fly   176 LAQSVLNVLWCLIAGKRIARQEDGTLRRLLDLMNRRSKLFD--------ICGGL--LAQFPWL-- 228
            |..|:.         .|:|..::......:|.......:|:        .|...  :|...||
plant   176 LTASIF---------FRVALGQNFHESNFIDKEKIEELVFEAETALASFTCSDFFPVAGLGWLVD 231

  Fly   229 ----RHVAPDRTGYNLIQQLNTELY---GFFMDTIEEHRRQLAKDPSPAESDLIYAYLQEMKDRS 286
                :|           ::||...|   ..|...|::|   |....|....|:|.:.|..:  ..
plant   232 WFSGQH-----------KRLNDVFYKLDALFQHVIDDH---LNPGRSKEHEDIIDSMLDAI--HK 280

  Fly   287 AGGESSTFNETQLVMT-----ILDFFIAGSQTTSNTINLALMVLAMRP--------DVQEKLFSQ 338
            .|.:||    .:|::.     :.:.|:||..|.:.|:..|:..|...|        :::|:|.|.
plant   281 EGKDSS----LELIIDHIKGFLANIFLAGIDTGALTMIWAMTELVKNPKLIKKVQGEIREQLGSN 341

  Fly   339 VTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATIL 403
             .|.:.....|..|         |:...|.|..|.....|:..||..:...|:.|||||....||
plant   342 -KARITEEDIDKVP---------YLKMVIKETFRLHPAAPLILPRETMAHIKVQGYDIPPKRRIL 396

  Fly   404 ISLRSVHLDKEHWKDPLEFRPERFIDSAGKCFKDEYF--MPFGMGRRRCLGDALARACIFSFLVR 466
            :::.::..|.:.|.:|.||.||||:||:.. ::.:::  :|||.|||.|.|..:..|.:...|:.
plant   397 VNVSAIGRDPKLWTNPEEFDPERFMDSSVD-YRGQHYELLPFGSGRRICPGMPMGIAAVELGLLN 460

  Fly   467 IVQHFSVVLPAG---------ESPSMVLLPGITLTPKPYKVQ 499
            ::..|...||.|         |:.::.::..:.|...|.:||
plant   461 LLYFFDWKLPDGMTHKDIDTEEAGTLTIVKKVPLQLVPVRVQ 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	p450	30..500	CDD:278495	128/531 (24%)
CYP71B20	NP_189249.1	p450	30..499	CDD:299894	125/527 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000