DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp305a1 and CYP71B19

DIOPT Version :9

Sequence 1:	NP_649151.1	Gene:	Cyp305a1 / 40161	FlyBaseID:	FBgn0036910	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_189248.1	Gene:	CYP71B19 / 822218	AraportID:	AT3G26170	Length:	502	Species:	Arabidopsis thaliana

Alignment Length:	560	Identity:	142/560 - (25%)
Similarity:	225/560 - (40%)	Gaps:	122/560 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ALIFLCAILIGFVIYSLISSARRPK----NFPPGPRFVPWLGNTLQFRKEASAVGGQHILFERWA 63
            |:.|||..||.||  |||..|::.|    |.||.|...|.:||..|. .|......|| |.||:
plant     2 AISFLCVFLITFV--SLIFFAKKIKRSKWNLPPSPPKFPVIGNLHQI-GELPHRSLQH-LAERY- 61

  Fly    64 KDFRSDLVGLKLGREYVVVALGHEMVKEVQLQEVFE--GRPDNFFLRLRTMGTR------KGITC 120
                ..::.|..|...:.|....|..:||......:  .||       :.:|||      |.|..
plant    62 ----GPVMLLHFGFVPITVVSSREAAEEVLRTHDLDCCSRP-------KLVGTRLLSRDFKDIGF 115

  Fly   121 TD-GQLWYEHRHFAMKQ---MRNVGYGRSQMEHHI-ELEAEELLGQLERT--EEQPIE---PVTW 175
            |. |..|...|.||:::   ::.|     |...|| |.|...|:.||..:  :..|::   .:.|
plant   116 TPYGNEWKARRKFALRELFCLKKV-----QSFRHIREEECNFLVKQLSESAVDRSPVDLSKSLFW 175

  Fly   176 LAQSVLNVLWCLIAGKRIARQEDGTLRRLLDLMNRR---------SKLFDICGGLLAQFPWL--- 228
            |..|   :|:.:..|:.....:.....::.:|:...         |..|.:.|     ..||
plant   176 LTAS---ILFRVALGQNFHESDFIDKEKIEELVFEAETALASFTCSDFFPVAG-----LGWLVDW 232

  Fly   229 ---RHVAPDRTGYNLIQQLNTELY---GFFMDTIEEHRRQLAKDPSPAESDLIYAYLQEMKDRSA 287
               :|           ::||...|   ..|...|::|   |....|....|:|.:.|..:..:
plant   233 FSGQH-----------KRLNDVFYKLDALFQHVIDDH---LNPGRSKEHEDIIDSMLDVIHKQ-- 281

  Fly   288 GGESSTFNET--QLVMTILDFFIAGSQTTSNTINLALMVLAMRP--------DVQEKLFSQVTAS 342
             ||.|:...|  .:...:.:.|:||..|.:.|:..|:..|...|        |::|:|.|. ...
plant   282 -GEDSSLELTIDHIKGFLANIFLAGIDTGAITMIWAVTELVKNPKLIKKVQGDIREQLGSN-KER 344

  Fly   343 VAAASTDAFPHLSRREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLR 407
            :.....:..|         |:...|.|..|.....|:..||..:...|:.|||||....||:::.
plant   345 ITEEDIEKVP---------YLKMVIKETFRLHPAAPLILPRETMAHIKVQGYDIPPKRRILVNVS 400

  Fly   408 SVHLDKEHWKDPLEFRPERFIDS----AGKCFKDEYFMPFGMGRRRCLGDALARACIFSFLVRIV 468
            ::..|.:.|.:|.||.||||:||    .|:.::   .:|||.|||.|.|..:..|.:...|:.::
plant   401 AIGRDPKLWTNPKEFDPERFMDSFVDYRGQHYE---LLPFGSGRRICPGMPMGIAAVELGLLNLL 462

  Fly   469 QHFSVVLPAG---------ESPSMVLLPGITLTPKPYKVQ 499
            ..|...||.|         |:.::.::..:.|...|.:||
plant   463 YFFDWKLPDGMTHKDIDTEEAGTLTIVKKVPLKLVPVRVQ 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	p450	30..500	CDD:278495	128/529 (24%)
CYP71B19	NP_189248.1	p450	25..499	CDD:299894	126/530 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000