DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp305a1 and CYP71B17

DIOPT Version :9

Sequence 1:	NP_649151.1	Gene:	Cyp305a1 / 40161	FlyBaseID:	FBgn0036910	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_189247.1	Gene:	CYP71B17 / 822216	AraportID:	AT3G26160	Length:	502	Species:	Arabidopsis thaliana

Alignment Length:	553	Identity:	135/553 - (24%)
Similarity:	231/553 - (41%)	Gaps:	110/553 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ALIFLCAILIGFVIYSLISS--ARRPKNFPPGPRFVPWLGNTLQ--------FRKEASAVGGQHI 57
            |:..||..||.||..:::..  .|...|.||.|..:|.:||..|        ||:.|...|  |:
plant     2 AISLLCLFLITFVSLTIVGCKIKRSIWNLPPSPPKLPVIGNLHQVGELPHRSFRRLAERTG--HV 64

  Fly    58 LFERWAKDFRSDLVGLKLGREYVVVALGHEMVKEVQLQEVFE--GRPDNFFLRLRTMGTRKGITC 120
            :.             |.||...|.|....|..:||......:  .||:....||.:.|. |.:..
plant    65 ML-------------LHLGFVPVTVISSREAAEEVLRTHDLDCCSRPNLVGSRLISRGF-KDLNF 115

  Fly   121 TD-GQLWYEHRHFAMKQMRNVGYGRSQMEHHI---ELEAEELLGQLERT--EEQPIE---PVTWL 176
            |. |:.|.|.|.|.:.::    :...:::..|   |:|...|:.:|..:  ::.|::   .:.||
plant   116 TPYGEEWKERRRFLVGEL----FCSKKLQSFIYIKEVECNFLVKKLSESAVDQSPVDLSKTLFWL 176

  Fly   177 AQSVLNVLWCLIAGKRIARQEDGTLRRLLDLMNRR---------SKLFDICG-GLLAQFPWLRHV 231
            |.|   :|:.:..|:.....|.....::.:|:...         |..|.|.| |.|..  |:
plant   177 AAS---ILFRVAFGQSFHESEFTDTDKIDELVFETETAQGSFTCSDFFPIAGLGWLVD--WI--- 233

  Fly   232 APDRTGYNLIQQLN---TELYGFFMDTIEEHRRQLAKDP--SPAESDLIYAYLQEMKDRSAGGES 291
                :|.:  ::||   .:|.......|::|     .:|  |....|::...|..|  ...|.:.
plant   234 ----SGQH--KRLNDVFLKLDALLQHVIDDH-----SNPGRSKDHKDIVDVMLDVM--HKQGKDD 285

  Fly   292 S---TFNETQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQV-------TASVAAA 346
            |   |.:..:.::|  :..|||..|.:.|:...:..||..|::.:|:..::       ...:...
plant   286 SLRLTIDHIKGLLT--NIIIAGIDTGALTMIWTMTELARNPEIMKKVQGEIRDRLGNNRERITKE 348

  Fly   347 STDAFPHLSRREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHL 411
            ..|..|         :::..|.|..|...:.|:..||..:...|:.|||||....||::..::..
plant   349 DLDKVP---------FLNLVIKETFRLHPVAPLLLPRETMAHVKVQGYDIPPKRRILVNAWAIGR 404

  Fly   412 DKEHWKDPLEFRPERFIDSAGKCFKDEYF--MPFGMGRRRCLGDALARACIFSFLVRIVQHFSVV 474
            |.:.|.||.||:|||||||... ::.::|  :|||.|||.|.|.|:..|.:...|:.::..|...
plant   405 DPKLWTDPEEFKPERFIDSPVD-YRGQHFELLPFGSGRRICPGMAMGMATLELGLLNLLYFFDWK 468

  Fly   475 LPAG---------ESPSMVLLPGITLTPKPYKV 498
            ||.|         |:.::.::..:.|...|.:|
plant   469 LPDGMSHKDIDTEEAGTLTVVKKVHLKLVPVRV 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	p450	30..500	CDD:278495	126/524 (24%)
CYP71B17	NP_189247.1	p450	30..499	CDD:299894	124/521 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000