DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp305a1 and CYP705A33

DIOPT Version :9

Sequence 1:	NP_649151.1	Gene:	Cyp305a1 / 40161	FlyBaseID:	FBgn0036910	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_001327676.1	Gene:	CYP705A33 / 821646	AraportID:	AT3G20960	Length:	521	Species:	Arabidopsis thaliana

Alignment Length:	554	Identity:	114/554 - (20%)
Similarity:	211/554 - (38%)	Gaps:	106/554 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SALIFLCAILIGFVIYSLISSARRPK-----NFPPGPRFVPWLGNTLQFRKEASAVGGQHILFER 61
            :..||:.......:.|||.  .::||     :.||.|..:|.:|:........|     |...::
plant    11 NCFIFILLCFFSLLCYSLF--FKKPKDSRGCDLPPSPPSLPIIGHLHLLLSSLS-----HKSLQK 68

  Fly    62 WAKDFRSDLVGLKLGREYVVVALGHEMVKEVQLQEVFEGRPDNFFLRLRTMG-TRKGITCTDGQL 125
            .:..: ..|:.|::....:::.....:..||              .|:..|. :.:|....|..|
plant    69 ISSKY-GPLLHLRIFNVPIILVSSASVADEV--------------FRIHDMNISSRGAAAIDESL 118

  Fly   126 WY-----------EHRHFAMKQMRNVGYGRSQMEHHIELEAEEL-------LGQLERTEEQPIEP 172
            .:           ::..|..|.:.........:|....|.||||       |.:.:..|...|..
plant   119 VFGSSGVVYAPYGDYLKFVKKIIATKLLRPQVLERSRGLRAEELQRLYNRILDKAKMNENVEIGK 183

  Fly   173 VTWLAQSVLNVLWCLIAGKRIARQEDGTLRRLLDLMNRRSKLFDICGGLLAQ-FPWLRHVAPDRT 236
            .   |..::|.::|.::..|...:|:|...|:              .||:|: :...:.:.....
plant   184 E---ATMLMNNIFCRMSMGRSFSEENGEAERV--------------RGLVAESYALAKKIFFASV 231

  Fly   237 GYNLIQQLNTELY--------GFFMDTIE----EHRRQLAKDPSPAESDLIYAYLQEMKDRSAGG 289
            ...|:::|...|:        ..|.:.:|    ||..:|  |....::|::...|....|.:|
plant   232 LRRLLKKLRIPLFKKDIMDVSNRFNELLEKILVEHNEKL--DEEHKDTDMMDVLLAAYADENA-- 292

  Fly   290 ESSTFNETQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAA----STDA 350
             ........:....::.|:.|:.|:..|....:..:....||.|:|..::.:.|..:    .||
plant   293 -EYKITRNHIKSFFVELFVGGTDTSVQTTQWTMAEIINNSDVLERLREEIDSVVGTSRMIQETD- 355

  Fly   351 FPHLSRREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEH 415
            .|:|      .|:.|.:.|..|.....|:. .|:.....::.|:.||:...::|:..:...|.:.
plant   356 IPNL------PYLQAVVKEGLRLHPPFPLL-TRKFEERCEIKGFYIPEKTFLIINAYAWMRDPDS 413

  Fly   416 WKDPLEFRPERFIDSAGKCFKDE-----YFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVL 475
            |:||.||:||||:.|:.....||     .::|||.|||.|.|..||...:.:.:..:||.|...:
plant   414 WEDPNEFKPERFLGSSRLGQVDEREEAQKYIPFGGGRRGCPGANLASIFVGTAIGVMVQCFDWGI 478

  Fly   476 PAGESPSMVLLPGITL--------TPKPYKVQFV 501
            ...:........|:||        ||.|..:.||
plant   479 KGDKINMEETFEGLTLTMVHPIKCTPIPRTLPFV 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	p450	30..500	CDD:278495	105/518 (20%)
CYP705A33	NP_001327676.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.000