DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp305a1 and CYP705A32

DIOPT Version :9

Sequence 1:	NP_649151.1	Gene:	Cyp305a1 / 40161	FlyBaseID:	FBgn0036910	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_188731.1	Gene:	CYP705A32 / 821645	AraportID:	AT3G20950	Length:	526	Species:	Arabidopsis thaliana

Alignment Length:	562	Identity:	122/562 - (21%)
Similarity:	230/562 - (40%)	Gaps:	122/562 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SALIFLCAILIGFVIYSLISSARRPK------NFPPGPRFVPWLG----NTLQFRKEASAVGGQH 56
            ::.||:...|...:.|||.  .|:||      :.||.|...| :|    |.|.....|..    |
plant    11 NSFIFILFCLFSLICYSLF--FRKPKDSRAGRDLPPSPPSFP-VGSPQSNNLHLLLSALV----H 68

  Fly    57 ILFERWAKDFRSDLVGLKLGREYVVVALGHEMVKEVQLQEVFEGRPDNFFLRLRTMGTRKGITCT 121
            ..|::.:..: ..|:.|::....:|:|....:.     .|:|:.:..|       :.:|......
plant    69 KSFQKISYKY-GPLLHLRVFHVPIVLASSASVA-----YEIFKAQDVN-------VSSRGHAPAG 120

  Fly   122 DGQL----------WYEHRHFAMKQMRNVGYGRSQMEHHIELEAEEL----LGQLERT-EEQPIE 171
            :..|          :.::..|..|.:.....|...:|...::.|:||    ...|::. :::.::
plant   121 ESLLFGSSSFFFAPYGDYFKFMRKLIATKLLGPQALERSRKIRADELDRFYRNLLDKAMKKESVD 185

  Fly   172 PVTWLAQSVLNVLWCLIAGKRIARQEDGTLRRLLDLMNRRSKLF-DICGGLLAQFPWLRHVAPDR 235
            .|...|:...|::..:|.| |...:::|...|:..|:...:.|. .|..|::...|.      .:
plant   186 IVEEAAKLNNNIICKMIMG-RSCSEDNGEAERVRGLVIESTALTKQIFLGMIFDKPL------KK 243

  Fly   236 TGYNLIQQLNTELYGFFMDTIE----EHRRQLAKDPSPAESDLIYAYLQEMKD---RSAGGESST 293
            .|.:|.|: :.:....|.:.:|    ||..::.|          :....:|.|   .:.|.|::.
plant   244 LGISLFQK-DIKSVSRFDELLEKILVEHEERMGK----------HYKANDMMDLLLEAYGDENAE 297

  Fly   294 FNETQ--LVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVA----AASTDAFP 352
            :..|:  :....:|..|||:.|::.||...:..|...|::.|:|..::.:.|.    ...|| .|
plant   298 YKITRNHIKSLFVDLVIAGTDTSAQTIEWTMAELINNPNILERLREEIESVVGNTRLVQETD-LP 361

  Fly   353 HLSRREAFDYMDAFIMEVQRFFHITPITGPRRALW------ATKLGGYDIPKNATILISLRSVHL 411
            :|      .|:.|.:.|..|..       |..|::      ..:|.|:.||:...:::::.::..
plant   362 NL------PYLQAVVKEGLRLH-------PPGAVFLRTFQERCELKGFYIPEKTLLVVNVYAIMR 413

  Fly   412 DKEHWKDPLEFRPERFIDSAGKCFKDEY------FMPFGMGRRRCLGDALARACIFSFLVRIVQH 470
            |.:.|:||.||:|||||.|:....:||.      :|||..|||.|.|..||...:.:.:..:.|.
plant   414 DPKLWEDPEEFKPERFIASSRSGQEDEIREEVLKYMPFSTGRRGCPGSNLAYVSVGTAIGVMAQC 478

  Fly   471 F----------------SVVLPAGESPSMVLLPG-ITLTPKP 495
            |                ::||...:  .::..|| .||.|.|
plant   479 FDWRIKGEKVNMNEAAGTLVLTMAQ--PLMCTPGPRTLNPLP 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	p450	30..500	CDD:278495	113/528 (21%)
CYP705A32	NP_188731.1	p450	16..514	CDD:299894	116/551 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000