DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp305a1 and CYP705A19

DIOPT Version :9

Sequence 1:	NP_649151.1	Gene:	Cyp305a1 / 40161	FlyBaseID:	FBgn0036910	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_188645.1	Gene:	CYP705A19 / 821553	AraportID:	AT3G20100	Length:	513	Species:	Arabidopsis thaliana

Alignment Length:	541	Identity:	127/541 - (23%)
Similarity:	227/541 - (41%)	Gaps:	81/541 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SALIFLCAILIGFVIYSLI---SSARRPK---NFPPGPRFVPWLGNTLQFRKEASAVGGQHILFE 60
            |..|||...|...|.|||.   .|:||..   :.||.|..:|.:|:.....  :|.|   |..|:
plant     8 SCFIFLLLCLFSLVCYSLFFRKPSSRRDAHGCDLPPSPPSLPVIGHLHLIL--SSLV---HKSFQ 67

  Fly    61 RWAKDFRSDLVGLKLGREYVVV----ALGHEMVKEVQLQEVFEGRPDNFFLRLRTMGTRKGITCT 121
            :.:.:: ..|:.|::....:|:    ::.:::.:...|.....|.|.  |......|:...|:..
plant    68 KISSNY-GPLLHLRIFNVPIVLVSSASVAYDIFRVHDLNVSSRGSPP--FEESLLFGSTGFISAP 129

  Fly   122 DGQLW-YEHRHFAMKQMRNVGYGRSQMEHHIELEAEELLGQLER-TEEQPIEPVTWLAQSVLNVL 184
            .|..: :..:|...|.:......||::....||| ...:..|:: |:::.:| :...|..:.|..
plant   130 YGDYFKFMKKHLVTKLLGPQALERSRLIRTNELE-RFYINLLDKATKKESVE-IGKEAMKLSNNS 192

  Fly   185 WCLIAGKRIARQEDGTLRRLLDL------MNRRSKLFDICGGLLAQFPWLRHVAPDRTGYNLIQQ 243
            .|.:...|...:|.|...|:..|      :.::..|.....|||           ::.|.:|.::
plant   193 ICKMIMGRSCLEEKGEAERVRGLIIESFYLTKKFFLAFTLRGLL-----------EKLGISLFKK 246

  Fly   244 LNTELYGF---FMDTIEEHRRQLAKDP--SPAESDLIYAYLQEMKDRSAGGESSTFNETQLVMTI 303
               |:.|.   |.|.:|.:.|:..:.|  ...::|:|.|.|...:|..|   .......|:...:
plant   247 ---EIMGVSRRFDDLLERYLREHEEKPDNEHQDTDMIDALLAAYRDEKA---EYKITRNQIKAFL 305

  Fly   304 LDFFIAGSQTTSNTINLALMVLAMRPD----VQEKLFSQVTASVAAASTDAFPHLSRREAFDYMD 364
            :|.||||:..::.|....:..:...|:    ::|::.|.|..|.....|| .|.|      .|:.
plant   306 VDIFIAGTDISALTTQGTMAEIINNPNIFVRIREEIDSVVGKSRLIQETD-LPKL------PYLQ 363

  Fly   365 AFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFID 429
            |.:.|..|....||:. .|......|:.|:.||.:.|::::..:|..|...|:||.||:||||:.
plant   364 AVVKEGLRLHPPTPLM-VREFQEGCKVKGFYIPASTTLVVNGYAVMRDPNVWEDPEEFKPERFLA 427

  Fly   430 SAGKCFKDEY------FMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAGESPSMVLLPG 488
            |:....:||.      ::.||.|||.|.|..:|...:.:.:..:||.|...:...:......:.|
plant   428 SSRLMQEDEIREQALKYIAFGSGRRGCPGANVAYIFVGTAIGMMVQCFDWRINGEKVDMKEAIGG 492

  Fly   489 ITLT-------------PKPY 496
            :.||             |||:
plant   493 LNLTLAHPLKCTPVARFPKPF 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	p450	30..500	CDD:278495	115/507 (23%)
CYP705A19	NP_188645.1	p450	13..508	CDD:386267	121/529 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000