DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp305a1 and CYP705A18

DIOPT Version :9

Sequence 1:	NP_649151.1	Gene:	Cyp305a1 / 40161	FlyBaseID:	FBgn0036910	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_001327402.1	Gene:	CYP705A18 / 821552	AraportID:	AT3G20090	Length:	524	Species:	Arabidopsis thaliana

Alignment Length:	571	Identity:	127/571 - (22%)
Similarity:	219/571 - (38%)	Gaps:	146/571 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LIFLCAILIGFVIYSLISSARRPK------NFPPGPRFVPWLGNTLQFRKEASAVGGQHILFERW 62
            :|.||  |...:.|||.  .|:||      :.||.|..:|.:|:.            .|:|....
plant    16 IILLC--LFSLLCYSLF--FRKPKGTRVGCDLPPSPPSLPIIGHL------------HHLLSSLT 64

  Fly    63 AKDFRSDLVGLKLGREY-------------VVV---ALGHEMVK--EVQLQEVFEGRPDNFFLRL 109
            .|..:      ||..:|             ::|   ::.:|:.|  :|.:........|...|
plant    65 HKSLQ------KLSSKYGPFLHLRIFSVPIILVSSASVAYEIFKAHDVNVSSRGAAAIDESLL-- 121

  Fly   110 RTMGTRKGITCTDGQLW-YEHRHFAMKQMRNVGYGRSQMEHHIELEAEEL-------LGQLERTE 166
              .|:...|....|..| :..:.||.|.:|     ...:|:...:.||||       |.:..:.|
plant   122 --FGSSSFIYAPYGDYWKFMKKIFATKLLR-----PQVLENSRGVRAEELKRFYRRILDKARKNE 179

  Fly   167 EQPIEPVTWLAQSVLNVLWCLIAGKRIARQEDG-----------------------TLRRLLDLM 208
            ...|...:.:   ::|.:.|.::..|...:|:|                       ||||||:.:
plant   180 NIEISKESAM---LMNNILCRMSMGRSFSEENGEAERVRGLVGESYALVKKIFFAATLRRLLEKL 241

  Fly   209 NRRSKLF--DICGGLLAQFPWLRHVAPDRTGYNLIQQLNTELYGFFMDTIEEHRRQLAKDPSPAE 271
              |..||  :|.|            ..||.. .|::::           |.||:.:|.|:..  .
plant   242 --RIPLFRKEIMG------------VSDRFD-ELLERI-----------IVEHKDKLEKEHQ--V 278

  Fly   272 SDLIYAYLQEMKDRSAGGESSTFNETQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLF 336
            .|::...|...:|::|   ........:....:|.|:.|:.|:..|....:..:...|::.:.|.
plant   279 MDMMDVLLAAYRDKNA---EYKITRNHIKSFFVDLFVGGTDTSVQTTQWTMAEIINNPNILQTLR 340

  Fly   337 SQVTASVAAA----STDAFPHLSRREAFDYMDAFIMEVQRFFHITPI---TGPRRALWATKLGGY 394
            .::.:.|..:    .|| .|:|      .|:.|.:.|..|.....|:   |...|.    ::.|:
plant   341 KEIDSVVGKSRLIHETD-IPNL------PYLQAVVKEGLRLHPPGPLLIRTFQERC----EMKGF 394

  Fly   395 DIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSAGKCFKDE-----YFMPFGMGRRRCLGDA 454
            .||:..|::|:..:|..|.:.|:||.||:||||:..:....:||     .::.||.|||.|.|..
plant   395 YIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLSYSRSGQEDEKEQTLKYLSFGGGRRGCPGVN 459

  Fly   455 LARACIFSFLVRIVQHFSVVLPAGESPSMVLLPGITLT-PKPYKVQFVKRT 504
            |....:.:.:..:||.|...:...:........|:.|| ..|.|...|.||
plant   460 LGYIFVGTAIGMMVQCFDWKIEGDKVNMEETYGGMNLTMVNPLKCTPVPRT 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	p450	30..500	CDD:278495	114/533 (21%)
CYP705A18	NP_001327402.1	CYP93	76..506	CDD:410748	103/483 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.000