DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp305a1 and CYP705A15

DIOPT Version :9

Sequence 1:	NP_649151.1	Gene:	Cyp305a1 / 40161	FlyBaseID:	FBgn0036910	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_566654.1	Gene:	CYP705A15 / 821548	AraportID:	AT3G20080	Length:	523	Species:	Arabidopsis thaliana

Alignment Length:	549	Identity:	120/549 - (21%)
Similarity:	217/549 - (39%)	Gaps:	95/549 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SALIFLCAILIGFVIYSLISSARRPK------NFPPGPRFVPWLGN-----TLQFRKEASAVGGQ 55
            :...|:...|...:.|||.  .|:||      :.||.|..:|.:|:     ::...:....:..:
plant    11 NCFFFVLLSLFSLLCYSLF--FRKPKEPRLHYDLPPSPPTLPIIGHLHLLLSVLVHRSLQTLSTK 73

  Fly    56 H--ILFERWAKDFRSDLVGLKLGREYVVVALGHEMVKEVQLQEVFEGRP---DNFFLRLRTMGTR 115
            :  ||:.| ...|...||.        ..::.:|:.:|..:.....|.|   |:.|     .|:.
plant    74 YGSILYLR-VFSFPVALVS--------SASIAYEIFREHDVNISSRGFPPTDDSLF-----AGSF 124

  Fly   116 KGITCTDGQLWYEHRHFAMKQMRNVGYGRSQMEHHIELEAEEL----LGQLERTEEQPIEPVTWL 176
            ...:...|..|    .|..|.:.....|...:|......|:||    ...|::..::....:...
plant   125 SFTSAPYGDYW----KFMKKLLVTNLLGPQALERSRGFRADELDLFYENLLDKAMKKESVDICVE 185

  Fly   177 AQSVLNVLWCLIAGKRIARQEDGTLRRL------LDLMNRRSKLFDICGGLLAQFPWLRHVAPDR 235
            |..:.|...|.:...|...:|:|...|:      ||.:.::..|.::.                |
plant   186 ALKLSNNSICKMIMGRSCSEENGEAERVRALATQLDGLTKKILLANML----------------R 234

  Fly   236 TGY-----NLIQQLNTELYGFFMDTIE----EHRRQLAKDPSPAESDLIYAYLQEMKDRSAGGES 291
            .|:     :|.::...::...|.:.:|    ||..:|  |.....:||:.|.|...:|::|   .
plant   235 AGFKKLVVSLFRKEMMDVSSRFDELLERILVEHEDKL--DMHHQGTDLVDALLAACRDKNA---E 294

  Fly   292 STFNETQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAA----STDAFP 352
            ...:...:.....|...|.:.|...|....:..:...|:|.|:|..::.:.|..|    .|| .|
plant   295 YKISRNHIKSFFADLLFASTDTFVQTTQWTVAEIINNPNVLERLRGEIDSVVGKARLIQETD-LP 358

  Fly   353 HLSRREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWK 417
            :|      .|:.|.:.|..|.....|:.. |.:....::||:.:|:..|::|:..:|..|.:.|:
plant   359 NL------PYLQAVVKEGLRLHPPGPLFA-RFSQEGCRIGGFYVPEKTTLMINAYAVMRDSDSWE 416

  Fly   418 DPLEFRPERFIDSAGKCFKDE------YFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLP 476
            ||.||:||||:.|:....:.|      .::.||.|||.|.|:.||...:.:.:..:||.|...:.
plant   417 DPDEFKPERFLASSRSEQEKERREQAIKYIAFGSGRRSCPGENLAYIFLGTAIGVMVQGFEWRIK 481

  Fly   477 AGESPSMVLLPGITLT-PKPYKVQFVKRT 504
            ..:........|::|| ..|.||..|.||
plant   482 EEKVNMEEANVGLSLTMAYPLKVTPVPRT 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	p450	30..500	CDD:278495	109/509 (21%)
CYP705A15	NP_566654.1	p450	30..511	CDD:299894	115/528 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000