DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp305a1 and CYP77A6

DIOPT Version :9

Sequence 1:	NP_649151.1	Gene:	Cyp305a1 / 40161	FlyBaseID:	FBgn0036910	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_187668.1	Gene:	CYP77A6 / 820222	AraportID:	AT3G10570	Length:	513	Species:	Arabidopsis thaliana

Alignment Length:	545	Identity:	123/545 - (22%)
Similarity:	222/545 - (40%)	Gaps:	87/545 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSALIFLCAILIGFVIYSLISSARRPK--NFPPGPRFVPWLGNTLQFRKEASAVGGQHILFERWA 63
            :|..:|...::...|:..|...:.:.|  ..||||...|.:||..||.:.    |.|   |..:.
plant    13 ISPSLFYTILISSLVLLILTRRSAKSKIVKLPPGPPGWPVVGNLFQFARS----GKQ---FYEYV 70

  Fly    64 KDFR---SDLVGLKLGREYVVVALGHEMVKEVQLQE--VFEGRP-DNFFLRLRTMGTRKGITCTD 122
            .|.|   ..:..|::|...:::.....:|.:|.:|.  :|..|| :|   ..||:.:....|...
plant    71 DDVRKKYGPIYTLRMGSRTMIIISDSALVHDVLIQRGPMFATRPTEN---PTRTIFSSNTFTVNA 132

  Fly   123 ---GQLWYEHRHFAMKQM------RNVGYGRSQMEHHIELEAEELLGQLERTEEQPIEPVTWLAQ 178
               |.:|...|...::.|      |..|        .:...|.:.|.:..::|.:..:.:.|:.:
plant   133 SAYGPVWRSLRKNMVQNMLSSIRFREFG--------SLRQSAMDKLVERIKSEAKDNDGLVWVLR 189

  Fly   179 SVLNVLWCLIA----GKRIARQE----DGTLRRLLDLMNRRSKLFDICGGLLAQFPWLRHVAPDR 235
            :.....:|::.    |..:..:.    |..::::|..:|.|   .|....:||.|     .:.:|
plant   190 NARFAAFCILLEMCFGIEMDEESILNMDQVMKKVLITLNPR---LDDYLPILAPF-----YSKER 246

  Fly   236 TGYNLIQQLNTELYGFFMDTIEEHRRQLAKDPSPAESDLIYAYLQEMKDRSAGGESSTFNETQLV 300
            .   ...::..|...|.:..||..||.:.| |...::...::||..:.|....|..:|.:..:||
plant   247 A---RALEVRCEQVDFIVKLIERRRRAIQK-PGTDKTASSFSYLDTLFDLKTEGRITTPSNEELV 307

  Fly   301 MTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDA 365
            ....:|...|:.||...|...:..|.:.|::|.:|:.::.::|.....:.    ...:...::.|
plant   308 SLCSEFLNGGTDTTGTAIEWGIAQLIVNPEIQSRLYDEIKSTVGDREVEE----KDVDKMVFLQA 368

  Fly   366 FIMEVQR-----FFHIT-PITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRP 424
            .:.|:.|     :|.:| .:|.|      |.:.|||:|....:...|..::.|.:.|.||.:|.|
plant   369 VVKEILRKHPPTYFTLTHSVTEP------TTVAGYDVPVGINVEFYLPGINEDPKLWSDPKKFNP 427

  Fly   425 ERFIDSAGKCFKDE---------YFMPFGMGRRRCLGDALARACIFSFLVRIVQHF--SVVLPAG 478
            :|||..     |:|         ..||||:|||.|.|.|:|...:...|.::||.|  |...|..
plant   428 DRFISG-----KEEADITGVTGVKMMPFGIGRRICPGLAMATVHVHLMLAKMVQEFEWSAYPPES 487

  Fly   479 ESPSMVLLPGITLTPKPYKVQFVKR 503
            |......|....:..||.:.....|
plant   488 EIDFAGKLEFTVVMKKPLRAMVKPR 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	p450	30..500	CDD:278495	117/509 (23%)
CYP77A6	NP_187668.1	PLN00168	55..512	CDD:215086	111/501 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.000