DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp305a1 and CYP76C3

DIOPT Version :9

Sequence 1:	NP_649151.1	Gene:	Cyp305a1 / 40161	FlyBaseID:	FBgn0036910	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_182082.2	Gene:	CYP76C3 / 819166	AraportID:	AT2G45580	Length:	515	Species:	Arabidopsis thaliana

Alignment Length:	536	Identity:	122/536 - (22%)
Similarity:	218/536 - (40%)	Gaps:	101/536 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LIFLCAILIGFVIYSLISSARRPKN---FPPGPRFVPWLGNTLQFRKEASAVG-GQHILFERWAK 64
            |.||..:   |..:...:..||..:   .||||..:|.:||..|       :| ..|.....::|
plant    13 LYFLLTL---FFFFFATAKTRRSSSTGTLPPGPPILPLVGNIFQ-------LGFNPHRSLAAFSK 67

  Fly    65 DFRSDLVGLKLGREYVVVALGHEMVKEVQLQEVFEGRPDNFFLRLRT----MGTRKGITCTDG-Q 124
            .: ..::.|||||...||....|..||.                |||    |..|   |..|. :
plant    68 TY-GPIMSLKLGRLTAVVISSPEAAKEA----------------LRTHDHVMSAR---TFNDALR 112

  Fly   125 LWYEHRH------------FAMKQM-------RNVGYGRSQMEHHIELEAEELLGQL-ERTEEQP 169
            .:..|:|            |..|.:       :|:...:|.....:| |...|:.:. ||.|...
plant   113 AFDHHKHSIVWIPPSARWRFLKKTITKYLLSPQNLDAIQSLRMRKVE-ELVSLVNEFRERGEAID 176

  Fly   170 IEPVTWLAQSVLNVLWCLIAGKRIARQEDGTLRRLLDLMNRRSKLFDICG--GLLAQFPWLRHVA 232
            :...:::..  .|::...:....:|..:..:  ...:..|....|.||.|  .:...|.::|.:.
plant   177 LARASFVTS--FNIISNALFSVDLATYDSNS--SSYEFHNTVVHLTDIAGIPNVGDYFQYMRFLD 237

  Fly   233 PDRTGYNLIQQLNTELYGFFMDTIE----EHRRQLAKDPSPAES-DLIYAYLQEMKDRSAGGESS 292
            ...|....:..:. :|:..|.:.|:    :...:..|:|..|.| |::.:.|          :.:
plant   238 LQGTRKKAVLCIE-KLFRVFQEFIDARLAKRFSRTEKEPKEASSIDMLDSLL----------DLT 291

  Fly   293 TFNETQLVMT-----ILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFP 352
            ..||.:|.|.     :||.|:||:.|.|:|:..|:..|....:...|..|::...:   ..:.|.
plant   292 QQNEAELTMNDLKHLLLDVFVAGTDTNSSTMEWAMTELFRSTEKMVKAQSEIRQVI---GQNGFV 353

  Fly   353 HLSRREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWK 417
            ..|...:..|:.|.:.|..|.....|:. ||::....::.|:.:|||..:::::.::..|...|:
plant   354 QESDIPSLPYLQAIVKETLRLHPAAPLI-PRKSESDVQIMGFLVPKNTQVVVNVWAIGRDASVWE 417

  Fly   418 DPLEFRPERFI----DSAGKCFKDEYFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAG 478
            :|::|.||||:    |..|:.|:   .:|||.|||.|.|.::|...:...|..::..|...|..|
plant   418 NPMKFEPERFLLRETDVKGRDFE---LIPFGSGRRMCPGISMALKTMHMVLASLLYSFDWKLQNG 479

  Fly   479 ESPSMVLLP---GITL 491
            ..|..:.:.   |:||
plant   480 VVPGNIDMSETFGLTL 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	p450	30..500	CDD:278495	116/507 (23%)
CYP76C3	NP_182082.2	p450	48..506	CDD:299894	111/498 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000