Protein Alignment Cyp305a1 and cyp2aa2

DIOPT Version :10

• Sequence 1: NP_649151.1
• Gene: Cyp305a1 / 40161
• FlyBaseID: FBgn0036910
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_001070926.1
• Gene: cyp2aa2 / 768294
• ZFINID: ZDB-GENE-061027-232
• Length: 498
• Species: Danio rerio
• Alignment Length: 507
• Identity: 157/507 - (30%)
• Similarity: 247/507 - (48%)
• Gaps: 50/507 - (9%)

  Fly     4 LIFLCAILIGFVIYSLISSARRPKNFPPGPRFVPWLG-------NTLQFRKEASAVGGQHILFER 61
            |||    |:.|.|:.:.|...|   |||||..:|::|       |.:.|::..|..||...:|
Zfish    21 LIF----LVLFEIFRINSYKGR---FPPGPTPLPFVGNLPHLLKNPMGFKRSLSEYGGLATVF-- 76

  Fly    62 WAKDFRSDLVGLKLGREYVVVALGHEMVKEVQLQEVFEGRP--DNFFLRLRTMGTRKGITCTDGQ 124
                         :||:..:.....::.||..:|:||.|||  ..|......:|.   |..|...
Zfish    77 -------------IGRQPAISINTIQLAKEALVQDVFSGRPPLPIFDWISHGLGI---IMVTFNH 125

  Fly   125 LWYEHRHFAMKQMRNVGYGRSQMEHHIELEAEELLGQLERTEEQPIEPVTWLAQSVLNVLWCLIA 189
            .|.:.|.||:..:||.|.|:..:|..:..|::.|:.::.:.|.:.:.|...|..:|.|::..::.
Zfish   126 SWRQQRRFALHTLRNFGLGKKTVEDRVLEESQYLIAEMLKDEGKSMNPQHALQNAVSNIICSIVF 190

  Fly   190 GKRIARQEDGTLRRLLDLMNRRSKLFDICGGLLAQF-PWLRHV-APDRTGYNLIQQLNTELYGFF 252
            |.|. ..::.....||.::|....|.....|.:... |:::|. .|    :..::|...:|:.|.
Zfish   191 GDRF-EYDNKRFEYLLKILNENIMLTGSAAGQIFNLVPFIKHFPGP----HQKVKQNADDLFNFI 250

  Fly   253 MDTIEEHRRQLAKDPSPAESDLIYAYLQEMKDRSAGGESSTFNETQLVMTILDFFIAGSQTTSNT 317
            .|..:||::.|..| ||  .|.|.|||.|::.:.:..| |||:|..||::..|.|:||:.||..|
Zfish   251 RDEAKEHKQTLDPD-SP--RDFIDAYLLEIEKQKSSKE-STFHEEHLVVSTSDLFLAGTDTTETT 311

  Fly   318 INLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFHITPITGP 382
            |...|:.|...|||||:...::   |.....|..|.:..|:...|..|.:.|:||..:|.|.. .
Zfish   312 IRWGLIYLIQNPDVQERCHEEI---VQVLGYDRLPSMDDRDKLPYTLATVHEIQRCGNIAPKL-L 372

  Fly   383 RRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSAGKCFKDEYFMPFGMGR 447
            ...:..|||.|||||:..||:.:..::..|||.||.|..|.||.|:|..|:..|.|||.||.:|.
Zfish   373 HETIRRTKLHGYDIPQGTTIIANFTAMFSDKELWKHPDAFNPENFLDENGQFSKPEYFFPFSLGP 437

  Fly   448 RRCLGDALARACIFSFLVRIVQHFSVVLPAGESP-SMVLLPGITLTPKPYKV 498
            |.|||:||||..:|.|:..::|......|....| .|..:.||..:|:|:.:
Zfish   438 RACLGEALARTELFLFITSLLQRIRFSWPPNAKPIDMDGIVGIVRSPEPFNI 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	CYP15A1-like	68..498	CDD:410744	136/434 (31%)
cyp2aa2	NP_001070926.1	cytochrome_P450	69..489	CDD:477761	139/450 (31%)