Protein Alignment Cyp305a1 and cyp2k20

DIOPT Version :10

• Sequence 1: NP_649151.1
• Gene: Cyp305a1 / 40161
• FlyBaseID: FBgn0036910
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: XP_021328803.1
• Gene: cyp2k20 / 562371
• ZFINID: ZDB-GENE-091113-5
• Length: 504
• Species: Danio rerio
• Alignment Length: 522
• Identity: 153/522 - (29%)
• Similarity: 253/522 - (48%)
• Gaps: 50/522 - (9%)

  Fly     2 SALIFLCAILIGFVIY--SLISSARRPKNFPPGPRFVPWLGN--TLQFRKEASAVGGQHILFERW 62
            |||  |.|:|:..|:|  |..|::::....||||:.:|.:||  ||...:....       |...
Zfish    14 SAL--LGALLLLLVLYLASSGSTSQKEGKEPPGPKPLPLVGNLLTLDLTRSFDT-------FFEL 69

  Fly    63 AKDFRSDLVGLKLGREYVVVALGHEMVKE--VQLQEVFEGRPDNFFLRLRTMGTRKGITCTDGQL 125
            :|.: .::..:.||....||.:|::.|||  |...|||..|......:|:  ....||..::|:.
Zfish    70 SKTY-GNIFQVFLGHRKTVVLVGYKTVKEALVNYAEVFGDREIGPGFKLK--DEEHGILFSNGEN 131

  Fly   126 WYEHRHFAMKQMRNVGYGRSQMEHHIELEAEELLGQLERTEEQPIEPVTWLAQSVLNVLWCLIAG 190
            |.|.|.||:..:|:.|.|:...|..|..|...|.|:.::.|.:|.:....:..:|.|::..::.|
Zfish   132 WKEMRRFALSNLRDFGMGKRGSEEKIIEEIHHLKGEFDKFEGKPFDTTQPVNYAVSNIISSIVYG 196

  Fly   191 KRIARQEDGTLRRLLDLMNRRSKLFDICGGLLAQ-----FPWLRHVAPDRTGY--NLIQQL--NT 246
            .|....:.    |..:::.|.::...: ||..:.     ||||.....:|...  |:.|..  ..
Zfish   197 SRFEYIDP----RFTEMVARANENVRV-GGSFSMMIYNIFPWLGPFLKNRAVVVKNITQNRAEKK 256

  Fly   247 ELYGFFMDTIEEHRRQLAKDPSP-AESDLIYAYLQEMKDRSAGGESSTFNETQLVMTILDFFIAG 310
            :|....::|:..|      ||.. .:|.||:    ::.|..:|.:.|.|:|..|::|:.:.|.||
Zfish   257 KLITALLETLNPH------DPRGFVDSFLIH----KLSDEKSGKKDSYFHEENLMLTVANLFAAG 311

  Fly   311 SQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFH 375
            :.||..|:...||::|..|.:|:::..::...:....    |.:..|:...|.||.|.|:||..:
Zfish   312 TDTTGTTLRWGLMLMAKYPHIQDRVQEEIDRVIGGRQ----PVVDDRKKLPYTDAVIHEIQRLAN 372

  Fly   376 ITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSAGKCFKDEYF 440
            |.|::.|.|........||.|.|..|::..|.||..|:..|:.|..|.||.|:|..|:..|.:.|
Zfish   373 IVPLSLPHRTTSDITFNGYFIKKGTTVVPLLTSVLKDESEWEKPNSFYPEHFLDEKGQFVKRDAF 437

  Fly   441 MPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAGESPSMVLLP---GITLTPKPYKVQFVK 502
            |||..|||.|||::|||..:|.|...::|.:....|.|.|...:.|.   ||||.|.|:|:..::
Zfish   438 MPFSAGRRVCLGESLARMELFLFFTSLLQSYRFTTPPGVSEDALDLKGIVGITLNPSPHKLCAIR 502

  Fly   503 RT 504
            |:
Zfish   503 RS 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	CYP15A1-like	68..498	CDD:410744	130/444 (29%)
cyp2k20	XP_021328803.1	cytochrome_P450	73..498	CDD:477761	130/446 (29%)