Protein Alignment Cyp305a1 and cyp2k19

DIOPT Version :10

• Sequence 1: NP_649151.1
• Gene: Cyp305a1 / 40161
• FlyBaseID: FBgn0036910
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_001073172.1
• Gene: cyp2k19 / 562304
• ZFINID: ZDB-GENE-091211-1
• Length: 502
• Species: Danio rerio
• Alignment Length: 530
• Identity: 150/530 - (28%)
• Similarity: 245/530 - (46%)
• Gaps: 76/530 - (14%)

  Fly     7 LCAILIGFVIYSLISSARRPKNFPPGPRFVPWLGN--TLQFRKEASAVGGQHILFERWAKDFRSD 69
            |.|:|:..|:|.:.|.:::....||||:.:|.|||  ||...:....       |...:|.: .:
Zfish    17 LAALLLFLVLYLVSSGSQKEGKEPPGPKPLPLLGNLLTLDLTRAFDT-------FFELSKTY-GN 73

  Fly    70 LVGLKLGREYVVVALGHEMVKE--VQLQEVFEGR---PDNFFLRLRTMGTRKGITCTDGQLWYEH 129
            :..:.||....||.:|::.|||  |...|.|..|   |.     .|.|....||..::|:.|.|.
Zfish    74 VFQVFLGPRKTVVLVGYKTVKEALVNYAEQFGDREIGPG-----FRIMNDEHGILFSNGENWKEM 133

  Fly   130 RHFAMKQMRNVGYGRSQMEHHIELEAEELLGQLERTEEQPIEPVTWLAQSVLNVLWCLIAGKRIA 194
            |.||:..:|:.|.|:...|..|..|...|.|:.::.|.:|.:....:..:|.|::..::.|.|.
Zfish   134 RRFALSNLRDFGMGKRGSEEKIIEEIHHLKGEFDKFEGKPFDTTQPVNYAVSNIISSIVYGSRF- 197

  Fly   195 RQEDGTLRRLLDLMNRRSKLFDICGGLLA-----QFPWLRHVAPDRTGYNLIQQLNTELYGFFMD 254
            ...|.....::|..|...::    ||.::     .|||   |.|......:|           ::
Zfish   198 EYTDPQFTEMVDRANENVRV----GGSVSMWFHEMFPW---VGPFLKSKRII-----------VE 244

  Fly   255 TIEEHRRQLAKDPSPAESDLIYAYLQ-----------------EMKDRSAGGESSTFNETQLVMT 302
            .|.:.|.|:.|        ||.|.|:                 ::.|..:|.:.|.|:|..|:||
Zfish   245 NIIQSRAQMTK--------LITALLETLNPNDPRGFVDSFLTRKLSDEKSGKKDSYFHEENLIMT 301

  Fly   303 ILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFI 367
            :.:.|:||:.||..|:...||::|..|.:|:::..::...:....    |.:..|:...|.||.|
Zfish   302 VTNLFVAGTDTTGTTLRWGLMLMAKYPQIQDRVQEEIDRVIGGRQ----PVVEDRKKLPYTDAVI 362

  Fly   368 MEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSAG 432
            .|:||..:|.|::.|.:........||.|.|..|::..|.||..|:..|:.|..|.||.|:|..|
Zfish   363 HEIQRLANIVPLSLPHKTTSDITFNGYFIKKGTTVVPLLTSVLKDESEWEKPNSFYPEHFLDEKG 427

  Fly   433 KCFKDEYFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAGESPSMVLLP---GITLTPK 494
            :..|.:.|:||..|||.|||::|||..:|.|...::|.:....|.|.|...:.|.   ||||.|.
Zfish   428 QFVKRDAFIPFSAGRRVCLGESLARMELFLFFTSLLQSYRFTTPPGVSEDELDLKGIVGITLNPS 492

  Fly   495 PYKVQFVKRT 504
            |:|:..::|:
Zfish   493 PHKLCAIRRS 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	CYP15A1-like	68..498	CDD:410744	130/459 (28%)
cyp2k19	NP_001073172.1	cytochrome_P450	71..496	CDD:477761	130/461 (28%)