Protein Alignment Cyp305a1 and cyp2k8

DIOPT Version :10

• Sequence 1: NP_649151.1
• Gene: Cyp305a1 / 40161
• FlyBaseID: FBgn0036910
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_001124095.1
• Gene: cyp2k8 / 561462
• ZFINID: ZDB-GENE-080721-19
• Length: 507
• Species: Danio rerio
• Alignment Length: 521
• Identity: 147/521 - (28%)
• Similarity: 244/521 - (46%)
• Gaps: 57/521 - (10%)

  Fly     5 IFLCAILIGFVIYSLISSARRPKNFPPGPRFVPWLGN--TLQFRKEASAVGGQHILFERWAKDFR 67
            :.|.|:|:..|:|.:..|:..|:: ||||:.:|.|||  ||..:       ..|:.....:|.:
Zfish    16 VLLSAVLLFLVVYLISISSSSPED-PPGPKPLPLLGNLHTLDLK-------NLHVSLWELSKKY- 71

  Fly    68 SDLVGLKLGREYVVVALGHEMVKEVQLQEVFEGRPDNFFLRLRTMGTRKGITCTDGQLWYEHRHF 132
            ..:..:.|||:.|||..|::.||:..:.:..|....:.....:.....:||...:|:.|...|.|
Zfish    72 GPVFKVHLGRKKVVVLAGYKTVKQALVNQAEEFGERDITPIFQDCNQGQGIVFANGERWRTMRRF 136

  Fly   133 AMKQMRNVGYGRSQMEHHIELEAEELLGQLERTEEQPIEPVTWLAQSVLNVLWCLIAGKRIARQE 197
            |:..:|:.|.|:...|..|..|...|.....:.|.||.:....:..:|.|::..::.|||. ..|
Zfish   137 ALSTLRDFGMGKKLSEEKIVDETRYLREVFMKFEGQPFDTTQPVNYAVSNIISAIVYGKRF-EYE 200

  Fly   198 DGTLRRLLDLMNRRSKLFDICGGLLAQF--------PWLRHVAPDRTGYNLIQQLNTELYGFFMD 254
            |...:   |::|:.:....:.|..:.|.        ||::          ..:||        |.
Zfish   201 DPAFQ---DMVNKANMNIRMIGSAVIQIYNMCPFLGPWIK----------TWRQL--------MK 244

  Fly   255 TIEEHRRQ-------LAKDPSPAE-SDLIYAYL-QEMKDRSAGGESSTFNETQLVMTILDFFIAG 310
            .:|..|||       |.:..:|.: ..||.::| ::...:..|.:.|:||:..|::|:.:.|.||
Zfish   245 NMESTRRQIQTLADVLQETLNPLDCRGLIDSFLIRKQNIQETGEKDSSFNDQNLLITVSNLFAAG 309

  Fly   311 SQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFH 375
            :.||..|:...||::|..|.:|:::..::...:....    |....|:...|.||.|.|.||..:
Zfish   310 TDTTGTTLRWGLMLMAKYPQIQDRVQEEIDQVLGGRE----PVAEDRKNLPYTDAVIHETQRLAN 370

  Fly   376 ITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSAGKCFKDEYF 440
            |.|:..|.:........||.|.|...:|..|.||..|:..|:.|..|.|:.|:|..|:..|.:.|
Zfish   371 ILPLNLPHKTSCDVTFNGYFIKKGTCVLPLLTSVLRDETEWETPDTFNPQHFLDEKGQLIKRDAF 435

  Fly   441 MPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAGES-PSMVLLP--GITLTPKPYKVQFVK 502
            |||..|||.|||::|||..:|.|...::|:|....|.|.| ..:.|.|  |:||.|.|:|:..|.
Zfish   436 MPFSAGRRACLGESLARMELFLFFTSLLQYFRFSPPPGASEDELDLTPVVGLTLNPSPHKLCAVI 500

  Fly   503 R 503
            |
Zfish   501 R 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	CYP15A1-like	68..498	CDD:410744	125/449 (28%)
cyp2k8	NP_001124095.1	cytochrome_P450	71..496	CDD:477761	125/451 (28%)