Protein Alignment Cyp305a1 and cyp2d6

DIOPT Version :9

• Sequence 1: NP_649151.1
• Gene: Cyp305a1 / 40161
• FlyBaseID: FBgn0036910
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_001015719.1
• Gene: cyp2d6 / 548436
• XenbaseID: XB-GENE-855872
• Length: 505
• Species: Xenopus tropicalis
• Alignment Length: 526
• Identity: 157/526 - (29%)
• Similarity: 248/526 - (47%)
• Gaps: 54/526 - (10%)

  Fly     1 MSALIFLCAILIGFVIYSL------------ISSARRP-KNFPPGPRFVPWLGNTLQ--FRKEAS 50
            ||.|..||...:|..:::|            ....|:| .:|||.|...|::||.||  ||
 Frog     1 MSLLSQLCPFALGCNVFTLGIIFTLLLLLLDFMKRRKPCTDFPPSPPSWPFVGNLLQMDFR---- 61

  Fly    51 AVGGQHILFERWAKDFRSDLVGLKLGREYVVVALGHEMVKEVQLQ---EVFEGRPDNFFLRLRTM 112
               ..|..|::.:|.: .|::.|::..:..||..|.|::||..:|   :..:..|.|.:..|..:
 Frog    62 ---DLHNSFKQLSKQY-GDVMSLRVFWKPTVVLNGFEVIKEALIQKSEDTADRPPFNLYEILGFV 122

  Fly   113 GTRKGITCTD-GQLWYEHRHFAMKQMRNVGYGRSQMEHHIELEAEELLGQLERTEEQPIEPVTWL 176
            |..|.:...: ||.|.:.|.|.:..:|:.|.|:..:|..:..||..|....:..:..|.:|...:
 Frog   123 GNNKAVVLANYGQSWKDLRRFTLSTLRDFGMGKKSLEERVRDEAGYLCDAFQSEQGGPFDPHVLI 187

  Fly   177 AQSVLNVLWCLIAGKRIARQEDGTLRRLLDLMNRRSKLFDICGG----LLAQFPWLRHVAPDRTG 237
            ..:|.||:..:|.|:|. ..:|....:||.|:....|..   .|    :::..||...| |...
 Frog   188 NTAVSNVICSIIFGERF-EYDDHKFLKLLCLIEESIKAE---SGPVPQIISSLPWSSKV-PGLA- 246

  Fly   238 YNLIQQLNTELYGFFMDTIEEHRRQLAKDPSPAESDLIYAYLQEMKDRSAGGESSTFNETQLVMT 302
             .|..|....:..:..:.|.||::..   .|....|.|.|::.||| ::.|.:.|.||:..|::|
 Frog   247 -RLFFQPRIHMLQYLQEIINEHKQTW---DSGHTRDFIDAFMLEMK-KAKGVKDSNFNDQNLLLT 306

  Fly   303 ILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFI 367
            ..|.|.|||:||:.|:...|:.:.:.||||.|:..::...:.....   |.:.......|.:|.|
 Frog   307 TADLFSAGSETTTTTLRWGLLFMLLYPDVQRKVQEEIDQVIGRTRK---PTMGDVLQMPYTNAVI 368

  Fly   368 MEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSAG 432
            .|:||:..|.|::.|..|...|.:.|:.|||...|:.:|.||..|::.|:.|.:|.||.|:|..|
 Frog   369 HEIQRYADIIPLSVPHMAYRDTHIKGFFIPKGTVIMTNLSSVLKDEKVWEKPFQFYPEHFLDRDG 433

  Fly   433 KCFKDEYFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAG-----ESPSMVLLPGITLT 492
            |..|.|.||.|..|||.|||:.|||..:|.|...::|.||..:|.|     |.|..|.|.    .
 Frog   434 KFVKREAFMAFSAGRRVCLGEQLARMELFLFFTSLLQRFSFQIPDGEPCLREDPVFVFLQ----V 494

  Fly   493 PKPYKV 498
            |..||:
 Frog   495 PHDYKI 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	p450	30..500	CDD:278495	147/484 (30%)
cyp2d6	NP_001015719.1	p450	52..501	CDD:306555	143/475 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000