Protein Alignment Cyp305a1 and Cyp2c24

DIOPT Version :9

• Sequence 1: NP_649151.1
• Gene: Cyp305a1 / 40161
• FlyBaseID: FBgn0036910
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_001258283.1
• Gene: Cyp2c24 / 499353
• RGDID: 1563697
• Length: 490
• Species: Rattus norvegicus
• Alignment Length: 520
• Identity: 147/520 - (28%)
• Similarity: 241/520 - (46%)
• Gaps: 47/520 - (9%)

  Fly     1 MSALIFLCAILIGFVIYSLISSARRPKNFPPGPRFVPWLGNTLQFR-KEASAVGGQHILFERWAK 64
            |..::.|...|...::.||...:......||||..:|.:||.||.. |:.|.      .|..::|
  Rat     1 MDPVLVLVLTLSCLLLLSLWRQSSGRGKLPPGPTPLPIIGNILQIDVKDISK------SFTNFSK 59

  Fly    65 DFRSDLVGLKLGREYVVVALGHEMVKEV--QLQEVFEGRPDNFFLRLRTMGTRKGITCTDGQLWY 127
            .: ..:..|..|.:..||..|:|.|||.  .|.|.|.||  ..|..:..|....|:..::|..|.
  Rat    60 IY-GPVFTLYFGPKPTVVVHGYEAVKEALDDLGEEFSGR--GSFPIVERMNNGLGVIFSNGTKWK 121

  Fly   128 EHRHFAMKQMRNVGYGRSQMEHHIELEAEELLGQLERTEEQPIEPVTWLAQSVLNVLWCLIAGKR 192
            |.|||::..:||.|.|:..:|..|:.||..|:.:|.:|.....:|...|:.:..||:..::...|
  Rat   122 ELRHFSLMTLRNFGMGKRSIEDRIQEEASCLVEELRKTNGSLCDPTFILSCAPSNVICSVVFHNR 186

  Fly   193 IARQEDGTLRRLLDLMNRRSKLFD-----ICGGLLAQFPWLRHVAPDRTGYNLIQQLNTELYGFF 252
            ...:::..| .|::.:|...|:.:     :|..|.|...:|    |.  .:|.:.:...|:..:.
  Rat   187 FDYKDENFL-NLMEKLNENFKILNSPWMQVCNALPAFIDYL----PG--SHNRVIKNFAEIKSYI 244

  Fly   253 MDTIEEHRRQLAKDPSPAESDLIYAYLQEMKDRSAGGESSTFNETQLVMTILDFFIAGSQTTSNT 317
            :..::||:..|..| :|  .|.|..:|.:| ::......:.|....|:.|:.|.|:|||:|||.|
  Rat   245 LRRVKEHQETLDMD-NP--RDFIDCFLIKM-EQEKHNPRTEFTIESLMATVSDVFVAGSETTSTT 305

  Fly   318 INLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFHITPITGP 382
            :...|::|....:|..|:..::...:.....   |.:..|....|.||.:.|:||:.::.|...|
  Rat   306 LRYGLLLLLKHTEVTAKVQEEIDHVIGRHRR---PCMQDRTRMPYTDAMVHEIQRYINLIPNNVP 367

  Fly   383 RRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSAGKCFKDEYFMPFGMGR 447
            ..|....:...|.|||...::.||.||..|.:.:.:|..|.|..|:|..|...|.:|||||..|:
  Rat   368 HAATCNVRFRNYVIPKGTDLVTSLTSVLHDDKEFPNPEVFDPGHFLDENGNFKKSDYFMPFSTGK 432

  Fly   448 RRCLGDALARACIFSFLVRIVQHFSVVLPAGESPSMVLLPGITLT---------PKPYKVQFVKR 503
            |.|:|:||||..:|..|..|||:|::       .|.|....|..|         |..|::.|:.|
  Rat   433 RMCVGEALARMELFLLLTTIVQNFNL-------KSFVDTKDIDTTPMANTFGRVPPSYQLCFIPR 490

  Fly   504  503
              Rat   491  490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	p450	30..500	CDD:278495	140/486 (29%)
Cyp2c24	NP_001258283.1	p450	30..487	CDD:278495	140/486 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920