Protein Alignment Cyp305a1 and cyp2k16

DIOPT Version :10

• Sequence 1: NP_649151.1
• Gene: Cyp305a1 / 40161
• FlyBaseID: FBgn0036910
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_001005963.2
• Gene: cyp2k16 / 449790
• ZFINID: ZDB-GENE-041010-37
• Length: 502
• Species: Danio rerio
• Alignment Length: 519
• Identity: 153/519 - (29%)
• Similarity: 236/519 - (45%)
• Gaps: 56/519 - (10%)

  Fly     7 LCAILIGFVIYSLISSARRPKNFPPGPRFVPWLGNTLQFRKEASAVGGQHILFERWAKDFRSDLV 71
            :|.:|:..|.|.|...::..:|.||||:.:|.|||.|..     .|...|:.....||.| ..:.
Zfish    17 ICFLLLLLVAYLLFLRSQSDENEPPGPKPLPLLGNLLML-----DVNKPHLSLCEMAKQF-GPVF 75

  Fly    72 GLKLGREYVVVALGHEMVKE--VQLQEVFEGRPDNFFLRLRTMGTRKGITCTDGQLWYEHRHFAM 134
            .:..|.:.|||..|::.||:  |...|.|..|.........|.|  .||...:|:.|.|.|.||:
Zfish    76 KVYFGPKKVVVLAGYKAVKQALVNYAEAFGDREIMPLFHDFTKG--HGIIFANGESWREMRRFAL 138

  Fly   135 KQMRNVGYGRSQMEHHIELEAEELLGQLERTEEQPIEPVTWLAQSVLNVLWCLIAGKRIARQEDG 199
            ..:|:.|.|:.::|..|..|...|..:.|:.|.:|.|....:..:..:|:..::.|:|. ...|.
Zfish   139 TNLRDFGMGKKKIEEKIIEETCHLREEFEKFEGKPFETAQLMNYAASSVISSIVYGRRF-EYTDP 202

  Fly   200 TLRRLLDLMNRRSKL-----------FDICGGLLAQFPWLR---HVAPDRTG---YNLIQQLNTE 247
            .||.::|..|...:|           |...|.||..:..|.   |:..:...   ..|.|.||.:
Zfish   203 QLRTMVDRANESVRLSGSASVQLYNMFPFLGPLLKNWRQLMKNLHLDIEEISELVNGLHQTLNHQ 267

  Fly   248 LYGFFMDTIEEHRRQLAKDPSPAESDLIYAYLQEMKDRSAGGESSTFNETQLVMTILDFFIAGSQ 312
            ....|:|:... |:|.|:|                    :|.:.|.|:|..|:.|:.:.|:||:.
Zfish   268 DLRGFVDSFLV-RKQYAED--------------------SGEKDSHFHEQNLIYTVGNLFVAGTD 311

  Fly   313 TTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFHIT 377
            |||.|:..:|:::|..|.:|:::..::...:....    |....|:...|.||.|.|.||..:|.
Zfish   312 TTSTTLRWSLLLMAKYPHIQDRVQEEIDQVIGGRQ----PVSEDRKNLPYTDAVIHETQRLANIV 372

  Fly   378 PITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSAGKCFKDEYFMP 442
            |::.|..........||.|.|...|...|.||..|::.|:.|..|.|..|:|..|:..|.:.|||
Zfish   373 PMSIPHMTSSDITFNGYFIKKGTCIFPLLTSVLWDEDEWETPHIFNPNHFLDEQGRFVKRDAFMP 437

  Fly   443 FGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAGES-PSMVLLP--GITLTPKPYKVQFVKR 503
            |..|||.|||::|||..:|.|...::|:|....|.|.| ..:.|.|  |.||.|..:|:..|||
Zfish   438 FSAGRRICLGESLARMELFLFFTSLLQYFRFTPPPGVSEDELELTPAVGFTLNPIAHKLCAVKR 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	CYP15A1-like	68..498	CDD:410744	129/451 (29%)
cyp2k16	NP_001005963.2	cytochrome_P450	71..496	CDD:477761	130/453 (29%)