Protein Alignment Cyp305a1 and cyp2k6

DIOPT Version :10

• Sequence 1: NP_649151.1
• Gene: Cyp305a1 / 40161
• FlyBaseID: FBgn0036910
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_956803.2
• Gene: cyp2k6 / 393481
• ZFINID: ZDB-GENE-040426-1571
• Length: 505
• Species: Danio rerio
• Alignment Length: 528
• Identity: 158/528 - (29%)
• Similarity: 246/528 - (46%)
• Gaps: 70/528 - (13%)

  Fly     7 LCAILIGFVIY--SLISSARRPKNFPPGPRFVPWLGNTLQFRKEASAVGGQHILFERWAKDFRSD 69
            |.|:|:..|||  |..||::..:.:||||:.:|.|||.             |||      |.:..
Zfish    18 LGALLLFLVIYLFSSSSSSQDKEKYPPGPKPLPLLGNL-------------HIL------DLKKT 63

  Fly    70 LVG-LKLGREY------------VVVALGHEMVKE--VQLQEVFEGRPDNFFLRLRTMGTRKGIT 119
            .:. |:|.::|            ||:..|:::|||  |.|.|.|..|..:........|  .||.
Zfish    64 YLSLLELSKKYGPIYTVYLGPKKVVILSGYKIVKEALVNLSEEFGDRDISPIFHDFNRG--YGIA 126

  Fly   120 CTDGQLWYEHRHFAMKQMRNVGYGRSQMEHHIELEAEELLGQLERTEEQPIEPVTWLAQSVLNVL 184
            .::|:.|.|.|.||:..:|:.|.||.:.|..|..|.:.:..:.|:....|.|....||.::.|::
Zfish   127 FSNGENWREMRRFALSTLRDFGMGRKRSEELIIEEIKYVKEEFEKFGGNPFETKLPLALAISNII 191

  Fly   185 WCLIAGKRIARQEDGTLRRLLDLMNRRSKLFDICGGLLAQ----FPWLRHVAPDRTGYNLIQQL- 244
            ..::...|. ...:..|.|::.......||   .|....|    |||||.:..:|.  .:::.|
Zfish   192 ASIVFSVRF-EYSNTKLHRMVGRAYENMKL---TGSPSVQIYNMFPWLRPIVANRN--QIVKNLR 250

  Fly   245 -----NTELYGFFMDTIEEHRRQLAKDPSPAESDLIYAYLQEMKDRSAGGESSTFNETQLVMTIL 304
                 |.||....|.|:         ||......:....:::.||..:|...|.:|...|..|:.
Zfish   251 DTFKQNEELINGVMKTL---------DPFNPRGIVDSFLIRQQKDEESGKTDSLYNSNNLYCTVN 306

  Fly   305 DFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIME 369
            :.|.||:.||..|:...|:::|..|::|.|:..::...:....    |.:..|:...|.||.|.|
Zfish   307 NLFGAGTDTTVTTLRWGLLLMAKYPEIQAKVQDEIERVIGGRQ----PVVEDRKNLPYTDAVIHE 367

  Fly   370 VQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSAGKC 434
            :|||..|:||..||:......|.||.|.|...:...|.||..|:..|:.|..|.|:.|::..|:.
Zfish   368 IQRFADISPIGAPRQTTCDVHLNGYFIKKGTPVFPLLVSVLRDENEWETPDSFNPKHFLNKQGQF 432

  Fly   435 FKDEYFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAGES-PSMVLLP--GITLTPKPY 496
            .|.:.|||||.|||.|:|::|||..:|.|...::|:|....|.|.| ..:.|.|  |.||.|||:
Zfish   433 VKKDAFMPFGAGRRVCIGESLARMELFLFFTSLLQYFRFTPPPGVSEDDLDLTPVVGFTLNPKPH 497

  Fly   497 KVQFVKRT 504
            ::..|||:
Zfish   498 QLCAVKRS 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	CYP15A1-like	68..498	CDD:410744	134/457 (29%)
cyp2k6	NP_956803.2	CYP2K	74..499	CDD:410757	132/445 (30%)