Protein Alignment Cyp305a1 and Cyp2t4

DIOPT Version :10

• Sequence 1: NP_649151.1
• Gene: Cyp305a1 / 40161
• FlyBaseID: FBgn0036910
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_001093654.1
• Gene: Cyp2t4 / 384724
• MGIID: 2686296
• Length: 503
• Species: Mus musculus
• Alignment Length: 530
• Identity: 165/530 - (31%)
• Similarity: 244/530 - (46%)
• Gaps: 69/530 - (13%)

  Fly     3 ALIFLCAILI-----GFVIYSLISSARRPKNFPPGPRFVPWLGNTLQFRK--------EASAVGG 54
            ||:.|..||:     |.|:.   ..|:..|:.||||..:|.|||.||.:.        |.|:..|
Mouse    14 ALLLLLLILMLLLWWGGVVR---RQAQMQKDLPPGPAPLPLLGNLLQLQSGDLDRVLMELSSHWG 75

  Fly    55 QHILFERWAKDFRSDLVGLKLGREYVVVALGHEMVKE--VQLQEVFEGRP-----DNFFLRLRTM 112
            .  :|..|            ||....||..|:|.:::  |...:.|.||.     |.|     |.
Mouse    76 P--VFTVW------------LGPLPAVVLCGYEALRDALVLQADAFSGRGAMAVFDRF-----TC 121

  Fly   113 GTRKGITCTDGQLWYEHRHFAMKQMRNVGYGRSQMEHHIELEAEELLGQLERTEEQPIEPVTWLA 177
            |  .||..::|..|:..|:||:..:|.:|.|||.:|..|..||..:|.:.:.|...|.:|...|.
Mouse   122 G--NGIVFSNGPRWHSLRNFALGVLRELGVGRSTIEDRILEEAACVLDEFQATMGAPFDPQQLLD 184

  Fly   178 QSVLNVLWCLIAGKRIARQEDGTLRRLLDLMNRRSKLFDICGGLLAQ----FPWLRHVAPDRTGY 238
            .:|.||:..::.|||. ...|...||||:|.   |..|.|.....|:    ||......|.  .:
Mouse   185 SAVSNVICTVVFGKRY-DYGDPEFRRLLNLF---SDNFCIMSSRWAEIYNMFPSFMDWIPG--PH 243

  Fly   239 NLIQQLNTELYGFFMDTIEEH--RRQLAKDPSPAESDLIYAYLQEMKDRSAGGESSTFNETQLVM 301
            |.|.:...||..|..:.|:.|  .||..:     ..|.|..:|.:| |:......|.|.:..|||
Mouse   244 NRIFKNFQELRLFISEQIQWHWQSRQTGE-----PRDFIDCFLDQM-DKEQQDLESHFQDETLVM 302

  Fly   302 TILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAF 366
            |..|.|..|::|||.|:...|:::...|:|..|:..::.|:|.....   |.:..|....|.:|.
Mouse   303 TTHDLFFGGTETTSTTLRYGLLIMLKYPEVAAKVQEELDATVGRTWA---PRIEDRARLPYTNAV 364

  Fly   367 IMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSA 431
            :.|:|||..:.|:..||.......|..:.:.|...::..|.|.|.|...:|||..|.|..|:|..
Mouse   365 LHEIQRFISVLPLGLPRALTRDVNLKNHFLHKGTFVIPLLVSAHRDPTQFKDPDHFNPTNFLDDH 429

  Fly   432 GKCFKDEYFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAGESPSMVLLP---GITLTP 493
            |:...::.||||.:|:|.|||..|||:.||.||..|:|.|| :||.|...::.|.|   |:...|
Mouse   430 GEFQNNDAFMPFALGKRMCLGAGLARSEIFLFLTAILQKFS-LLPVGSPANINLNPQCTGLGNVP 493

  Fly   494 KPYKVQFVKR 503
            ..::::.|.|
Mouse   494 PAFQLRLVAR 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	CYP15A1-like	68..498	CDD:410744	139/445 (31%)
Cyp2t4	NP_001093654.1	Cyp2F	74..498	CDD:410762	142/460 (31%)