Protein Alignment Cyp305a1 and Cyp2j3

DIOPT Version :10

• Sequence 1: NP_649151.1
• Gene: Cyp305a1 / 40161
• FlyBaseID: FBgn0036910
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_786942.1
• Gene: Cyp2j3 / 313375
• RGDID: 631442
• Length: 502
• Species: Rattus norvegicus
• Alignment Length: 514
• Identity: 151/514 - (29%)
• Similarity: 263/514 - (51%)
• Gaps: 46/514 - (8%)

  Fly     4 LIFLCAILIGFVIYSLISSARRPKNFPPGPRFVPWLGNTLQFRKEASAVGGQHILFERWAKDFRS 68
            ::.|.|:.  |:..:.....|||||:||||..:|.:|.......:.     .|:..:::.|.: .
  Rat    20 ILLLAAVT--FLFLADFLKHRRPKNYPPGPWRLPLVGCLFHLDPKQ-----PHLSLQQFVKKY-G 76

  Fly    69 DLVGLKLGREYVVVALGHEMVKEV--QLQEVFEGRPDNFFLRLRTMGTRKGITCTDGQLWYEHRH 131
            :::.|.......||..|..::||:  |::..|..||  ..|..:.:..:.|:..:.||.|.|.|.
  Rat    77 NVLSLDFANIPSVVVTGMPLIKEIFTQMEHNFLNRP--VTLLRKHLFNKNGLIFSSGQTWKEQRR 139

  Fly   132 FAMKQMRNVGYGRSQMEHHIELEAEELLGQLERTEEQPIEPVTWLAQSVLNVLWCLIAGKRIARQ 196
            ||:..:||.|.|:..:|..|:.||..|:..::.....|.:|...:.::|.|::..:..|:|. ..
  Rat   140 FALMTLRNFGLGKKSLEQRIQEEAYHLVEAIKDEGGLPFDPHFNINKAVSNIICSVTFGERF-EY 203

  Fly   197 EDGTLRRLLDLMNR--------RSKLFDICGGLLAQFPWLRHVAPDRTGYNLIQQLNTELYGFFM 253
            .|...:.:|.|::.        ..:|::|...:|...|     ...:|.::..::|..    |..
  Rat   204 HDSQFQEMLRLLDEAMCLESSMMCQLYNIFPRILQYLP-----GSHQTLFSNWRKLKL----FIS 259

  Fly   254 DTIEEHRRQLAKDPSPAE-SDLIYAYLQEM---KDRSAGGESSTFNETQLVMTILDFFIAGSQTT 314
            |.|:.|||    |..|.| .|.|.|:|:||   .|::    :::|||..|:.:.||.|.||::||
  Rat   260 DIIKNHRR----DWDPDEPRDFIDAFLKEMAKYPDKT----TTSFNEENLICSTLDLFFAGTETT 316

  Fly   315 SNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFHITPI 379
            |.|:..||:.:|:.|:||||:.:::...:.....   |:|:.|::..|.:|.|.||||..:|.|.
  Rat   317 STTLRWALLCMALYPEVQEKMQAEIDRVIGQGRQ---PNLADRDSMPYTNAVIHEVQRIGNIIPF 378

  Fly   380 TGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSAGKCFKDEYFMPFG 444
            ..||.....|.|.|:::||...||.:|.::|.|.:.|..|..|.||.|::: |:..|.|.|:||.
  Rat   379 NVPREVAVDTYLAGFNLPKGTMILTNLTALHRDPKEWATPDTFNPEHFLEN-GQFKKRESFLPFS 442

  Fly   445 MGRRRCLGDALARACIFSFLVRIVQHFSVVLPAGESPSMVLLPGITLTPKPYKVQFVKR 503
            ||:|.|||:.|||:.:|.|:..::|.|:...|..|..|:.....:|::|..:::..:.|
  Rat   443 MGKRACLGEQLARSELFIFITSLIQKFTFKPPVNEKLSLQFRMSVTISPVSHRLCAIPR 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	CYP15A1-like	68..498	CDD:410744	134/443 (30%)
Cyp2j3	NP_786942.1	CYP2J	75..496	CDD:410755	134/445 (30%)