Protein Alignment Cyp305a1 and Cyp2u1

DIOPT Version :10

• Sequence 1: NP_649151.1
• Gene: Cyp305a1 / 40161
• FlyBaseID: FBgn0036910
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_001380742.1
• Gene: Cyp2u1 / 310848
• RGDID: 1309433
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 540
• Identity: 164/540 - (30%)
• Similarity: 260/540 - (48%)
• Gaps: 78/540 - (14%)

  Fly     5 IFLC--AILIGFVIYSLISSARRPKNFPPGPRFVP------------------WLGNTLQFRKEA 49
            :.||  |:|:.:|..    ..:|....||||:..|                  |||:..|
  Rat    28 LLLCGLAVLLDWVWL----QRQRAGGIPPGPKPRPLVGNFGYLLLPRFLRLHFWLGSGSQ----- 83

  Fly    50 SAVGGQHILFERWAKDFRSDLVGLKLGREYVVVALGHEMVKE--VQLQEVFEGRPDNFFLRLRTM 112
            :...|:|:...|.|:.: .::....:|...|||....:.|:|  ||..|||..||....:.:.|
  Rat    84 TDTVGRHVYLARLARVY-GNIFSFFIGHRLVVVLSDFQSVREALVQQAEVFSDRPRMPLISILT- 146

  Fly   113 GTRKGITCTD-GQLWYEHRHFAMKQMRNVGYGRSQMEHHIELEAEELLGQLERTEEQPIEPVTWL 176
             ..|||.... |.:|.:.|.|:...:|:.|.|:..:|..|..|...:..::::..|.|..|...:
  Rat   147 -KEKGIVFAHYGPIWKQQRRFSHSTLRHFGLGKLSLEPRIIEEFAYVKAEMQKHGEAPFSPFPVI 210

  Fly   177 AQSVLNVLWCLIAGKRIARQEDGT---LRRLLDLMNR------RSKLF--DICGGLLAQFPWLRH 230
            :.:|.|::..|..|:|.    |.|   .:::||.|:|      .|:||  ::|       ||..:
  Rat   211 SNAVSNIICSLCFGQRF----DYTNKEFKKVLDFMSRGLEICLHSQLFLINLC-------PWFYY 264

  Fly   231 V--APDRTGYNLIQQLNTELYGFFMDTIEEHRRQL-AKDPSPAESDLIYAYL---QEMKDRSAGG 289
            :  .|    :..::|:..::..|..:.|:||:..| |.:|    .|.|..||   ||.||:..|
  Rat   265 LPFGP----FKELRQIERDITCFLKNIIKEHQESLDANNP----QDFIDMYLLHTQEEKDKCKG- 320

  Fly   290 ESSTFNETQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHL 354
              :.|:|..|...|.|.||||:.||:|::...|:.:::.|.||:|:..::...:   ..|..|.|
  Rat   321 --TNFDEDYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPGVQKKVHEEIERVI---GRDRAPSL 380

  Fly   355 SRREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDP 419
            :.:....|.:|.||||||...:.|:..|......|.|.||.|||...:|.:|.|:|.|...|:.|
  Rat   381 TDKAQMPYTEATIMEVQRLSMVVPLAIPHMTSEKTVLQGYSIPKGTVVLPNLWSIHRDPVIWEKP 445

  Fly   420 LEFRPERFIDSAGKCFKDEYFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAG-ESPSM 483
            .:|.|.||:|..|:..|.|.|:|||:|:|.|:|:.||:..:|...|.::|.|:..||.| |.|.|
  Rat   446 DDFCPHRFLDDQGQLLKRETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSFTFALPEGSEKPIM 510

  Fly   484 VLLPGITLTPKPYKVQFVKR 503
            ....|:||.|.|:.|...||
  Rat   511 TGRFGLTLAPHPFNVTVSKR 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	CYP15A1-like	68..498	CDD:410744	142/450 (32%)
Cyp2u1	NP_001380742.1	CYP2U1	100..525	CDD:410759	142/452 (31%)