Protein Alignment Cyp305a1 and Cyp2b3

DIOPT Version :9

• Sequence 1: NP_649151.1
• Gene: Cyp305a1 / 40161
• FlyBaseID: FBgn0036910
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_775416.1
• Gene: Cyp2b3 / 286953
• RGDID: 628627
• Length: 491
• Species: Rattus norvegicus
• Alignment Length: 527
• Identity: 151/527 - (28%)
• Similarity: 256/527 - (48%)
• Gaps: 63/527 - (11%)

  Fly     2 SALIFLCAILIGFVIYSLISSARRPKNFPPGPRFVPWLGNTLQ-----FRKEASAVGGQHILFER 61
            ::::.|.|:|:.|:::.:...|:...:.|||||.:|.|||.||     |||....:..:|
  Rat     3 TSVLLLLAVLLSFLLFLVRGHAKVHGHLPPGPRPLPLLGNLLQMDRGGFRKSFIQLQEKH----- 62

  Fly    62 WAKDFRSDLVGLKLGREYVVVALGHEMVKE--VQLQEVFEGRPDNFFLRLRTMGTRKGITCTDGQ 124
                  .|:..:..|...||:..|.:.::|  |...|.|.||  .....|:.:....|::..:.:
  Rat    63 ------GDVFTVYFGPRPVVMLCGTQTIREALVDHAEAFSGR--GIIAVLQPIMQEYGVSFVNEE 119

  Fly   125 LWYEHRHFAMKQMRNVGYGRSQMEHHIELEAEELLGQLERTEEQPIEPVTWLAQSVL-NVLWCLI 188
            .|...|...:..||:.|.|:..:|..|:.||:.|:.:|:..:...::| |:|.|.|. |::..::
  Rat   120 RWKILRRLFVATMRDFGIGKQSVEDQIKEEAKCLVEELKNHQGVSLDP-TFLFQCVTGNIICSIV 183

  Fly   189 AGKRIARQEDGTLRRLLDLMNR--------RSKLFDICGGLLAQFPWLRHVAPDRTGYNLIQQLN 245
            .|:|. ...|....|||||:.|        .|::|::....|..||.:.     |..|..::
  Rat   184 FGERF-DYRDRQFLRLLDLLYRTFSLISSFSSQMFEVYSDFLKYFPGVH-----REIYKNLK--- 239

  Fly   246 TELYGFFMDTIEEHRRQLAKDPSPAESDLIYAYLQEMKDRSAGGESSTFNETQLVMTILDFFIAG 310
             |:..:...::|.||..|  ||: |..|.|..:|..| ::......:.|:...|::::|..|:||
  Rat   240 -EVLDYIDHSVENHRATL--DPN-APRDFIDTFLLHM-EKEKLNHYTEFHHWNLMISVLFLFLAG 299

  Fly   311 SQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFH 375
            :::||||:....:::...|.|.||:..::...:   .:...|.|..|....|.:|.|.|:|||..
  Rat   300 TESTSNTLCYGFLLMLKYPHVAEKVQKEIDQVI---GSQRVPTLDDRSKMPYTEAVIHEIQRFSD 361

  Fly   376 ITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSAGKCFKDEYF 440
            ::|:..|.|....|...||.:|||..:...|.|...|.::::.|..|.||.|:|:.|...|.|.|
  Rat   362 VSPMGLPCRITKDTLFRGYLLPKNTEVYFILSSALHDPQYFEQPDTFNPEHFLDANGALKKCEAF 426

  Fly   441 MPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAGESPSMVLLPGITLTPKP---------Y 496
            |||.:|:|.|||:.:||:.:|.|...|:|::||..|...:.       |.:|||.         |
  Rat   427 MPFSIGKRMCLGEGIARSELFLFFTTILQNYSVSSPVDPNT-------IDMTPKESGLAKVAPVY 484

  Fly   497 KVQFVKR 503
            |:.||.|
  Rat   485 KICFVAR 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	p450	30..500	CDD:278495	143/494 (29%)
Cyp2b3	NP_775416.1	p450	42..488	CDD:278495	135/483 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000008
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920