Protein Alignment Cyp305a1 and Cyp2j12

DIOPT Version :10

• Sequence 1: NP_649151.1
• Gene: Cyp305a1 / 40161
• FlyBaseID: FBgn0036910
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_001093652.1
• Gene: Cyp2j12 / 242546
• MGIID: 3717097
• Length: 502
• Species: Mus musculus
• Alignment Length: 517
• Identity: 156/517 - (30%)
• Similarity: 261/517 - (50%)
• Gaps: 45/517 - (8%)

  Fly     3 ALIFLCAILIGFVIYSLIS---SARRPKNFPPGPRFVPWLGNTLQFRKEASAVGGQHILFERWAK 64
            ||:....:::..|.:.|::   ..:||||:||||..:|::||..|...|.     .|::.:::.|
Mouse    14 ALLHFKTLVLAAVTFMLLAHYLKTQRPKNYPPGPWRLPFVGNLFQLDLEQ-----PHVVIQQFVK 73

  Fly    65 DFRSDLVGLKLGREYVVVALGHEMVKEV--QLQEVFEGRPDNFFLRLRTMGTRKGITCTDGQLWY 127
            .: .:|..|..|....|:..|..::|||  .:::.|..||.. .:|.|.. ...|:..::||.|.
Mouse    74 KY-GNLTSLDFGNIPSVIITGLPLIKEVFTNMEQNFLNRPIT-PIRKRVF-NNNGLIISNGQTWK 135

  Fly   128 EHRHFAMKQMRNVGYGRSQMEHHIELEAEELLGQLERTEEQPIEPVTWLAQSVLNVLWCLIAGKR 192
            |.|.||:..::|.|.|:..:|..|:.||:.|:..:...:.||.:|...:..:|.|::.....|:|
Mouse   136 EQRRFALMTLKNFGLGKKSLEQRIQKEADCLVEAIGEEKGQPFDPHFKINSAVSNIICTFAFGER 200

  Fly   193 IARQEDGTLRRLLDLMNRRS--------KLFDICGGLLAQFPWLRHVAPDRTGYNLIQQLNTELY 249
            . ..||.....||.|::..:        :|:::       ||.:....|.  .:..:.:...:|.
Mouse   201 F-EYEDSHFHELLRLLDEATCLEASMMCQLYNV-------FPSIIQYVPG--SHQTVLRNWEKLK 255

  Fly   250 GFFMDTIEEHRRQLAKDPSPAE-SDLIYAYLQEMKDRSAGGESST--FNETQLVMTILDFFIAGS 311
            .|....:|.||    ||.:|.| .|.|.|:|.||   |..|:.:|  |||..|:.:.||.|.|||
Mouse   256 LFIYQMMESHR----KDWNPDEPRDFIDAFLTEM---SKYGDKTTTSFNEENLINSTLDLFFAGS 313

  Fly   312 QTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFHI 376
            :||:||:..||:.:...|:||||:.|::...:.....   |....|::..|.:|.|.||.|..:|
Mouse   314 ETTTNTLRWALLYITTNPEVQEKVHSEIDRVIGHGRQ---PSTDDRDSMPYTNAVIHEVLRMGNI 375

  Fly   377 TPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSAGKCFKDEYFM 441
            .|:..||.....:.|.|:.:||...:|.:|.::|.|.:.|..|..|.||.|::: |:..|.|.|:
Mouse   376 LPMNVPREVTADSTLAGFHLPKGTMVLTNLTALHRDPKEWATPNTFNPEHFLEN-GQFKKRESFL 439

  Fly   442 PFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAGESPSMVLLPGITLTPKPYKVQFVKR 503
            ||.:|:|.|.|:.|||:.:|.|...::|.|:...|..|..|:....|:||:|..:.:..|.|
Mouse   440 PFSLGKRACPGEQLARSELFIFFTALMQKFTFKPPINEKLSLKFRNGLTLSPVSHCICAVPR 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	CYP15A1-like	68..498	CDD:410744	135/442 (31%)
Cyp2j12	NP_001093652.1	cytochrome_P450	75..496	CDD:477761	135/444 (30%)