Protein Alignment Cyp305a1 and Cyp2d10

DIOPT Version :9

• Sequence 1: NP_649151.1
• Gene: Cyp305a1 / 40161
• FlyBaseID: FBgn0036910
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_034135.2
• Gene: Cyp2d10 / 13101
• MGIID: 88602
• Length: 504
• Species: Mus musculus
• Alignment Length: 520
• Identity: 161/520 - (30%)
• Similarity: 250/520 - (48%)
• Gaps: 51/520 - (9%)

  Fly     7 LCAILIGFVIYSLI-----SSARRPKNFPPGPRFVPW--LGNTLQFRKEASAVGGQHILFERWAK 64
            |.::.|..||:.|:     ...|....:||||  |||  |||.||       |...::.:..:..
Mouse     9 LWSVAIFTVIFILLVDLMHRHQRWTSRYPPGP--VPWPVLGNLLQ-------VDLDNMPYSLYKL 64

  Fly    65 DFR-SDLVGLKLGREYVVVALGHEMVKEVQLQ-----------EVFEGRPDNFFLRLRTMGTRKG 117
            ..| .|:..|::|.:.:||..|.:.:|||.|.           .:||      :|.::. |::..
Mouse    65 QNRYGDVFSLQMGWKPMVVINGLKAMKEVLLTCGEDTADRPQVPIFE------YLGVKP-GSQGV 122

  Fly   118 ITCTDGQLWYEHRHFAMKQMRNVGYGRSQMEHHIELEAEELLGQLERTEEQPIEPVTWLAQSVLN 182
            :....|..|.|.|.|::..:||.|.|:..:|..:..||..|.........|||.|.|.|..:|.|
Mouse   123 VLAPYGPEWREQRRFSVSTLRNFGLGKKSLEDWVTKEARHLCDAFTAQAGQPINPNTMLNNAVCN 187

  Fly   183 VLWCLIAGKRIARQEDGTLRRLLDLMNRRSKLFDICG---GLLAQFPWLRHVAPDRTGYNLIQQL 244
            |:..||..:|. ..||..|.|:..::  ...|.:|.|   .:|..||.|..: |...|  .:.|.
Mouse   188 VIASLIFARRF-EYEDPYLIRMQKVL--EDSLTEISGLIPEVLNMFPILLRI-PGLPG--KVFQG 246

  Fly   245 NTELYGFFMDTIEEHRRQLAKDPSPAESDLIYAYLQEMKDRSAGGESSTFNETQLVMTILDFFIA 309
            ...|.....:.:.|:|.  ..||.....:|..|:|.|: ::..|...|:||:..|.|.:||.|.|
Mouse   247 QKSLLAIVENLLTENRN--TWDPDQPPRNLTDAFLAEI-EKVKGNAESSFNDENLRMVVLDLFTA 308

  Fly   310 GSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFF 374
            |..|||.|::.||:::.:.||||.::..::.|.:...   ..|.::.:....|.:|.|.|||||.
Mouse   309 GMVTTSTTLSWALLLMILHPDVQRRVQQEIDAVIGQV---RHPEMADQARMPYTNAVIHEVQRFG 370

  Fly   375 HITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSAGKCFKDEY 439
            .|.|:..||......::..:.|||.:.::.::.||..|:..|:.||.|.||.|:|:.|...|.|.
Mouse   371 DIAPLNLPRITSRDIEVQDFLIPKGSILIPNMSSVLKDETVWEKPLRFHPEHFLDAQGHFVKPEA 435

  Fly   440 FMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAGE-SPSMVLLPGITLTPKPYKVQFVKR 503
            ||||..|||.|||:.|||..:|.|...::||||..:|.|: .|..:.:....:.|.||::..|.|
Mouse   436 FMPFSAGRRSCLGEPLARMELFLFFTCLLQHFSFSVPNGQPRPRNLGVFPFPVAPYPYQLCAVMR 500

  Fly   504  503
            Mouse   501  500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	p450	30..500	CDD:278495	153/487 (31%)
Cyp2d10	NP_034135.2	p450	37..496	CDD:278495	153/486 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920