Protein Alignment Cyp305a1 and cyp2e1.2

DIOPT Version :10

• Sequence 1: NP_649151.1
• Gene: Cyp305a1 / 40161
• FlyBaseID: FBgn0036910
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: XP_031758885.1
• Gene: cyp2e1.2 / 101731204
• XenbaseID: XB-GENE-6040025
• Length: 489
• Species: Xenopus tropicalis
• Alignment Length: 516
• Identity: 138/516 - (26%)
• Similarity: 247/516 - (47%)
• Gaps: 39/516 - (7%)

  Fly     1 MSALIFLCAILIGFVIYSLISSAR-RPKNFPPGPRFVPWLGN--TLQFRKEASAVGGQHILFERW 62
            |..:..|.::::...:|.:....: ||:||||||:.:|.:||  .:..||       .|:.|...
 Frog     1 MDPVSVLLSVVVCIFLYKVFYGGKERPENFPPGPKPLPLIGNLHIMNMRK-------PHLTFMEL 58

  Fly    63 AKDFRSDLVGLKLGREYVVVALGHEMVKEVQLQEVFEGRPDNFFLRLR-----TMGTRKGITCTD 122
            ||.:.| :...:||.|.:||..|.:.||:..:...     :.|..|.:     .:....||....
 Frog    59 AKTYGS-VFSFQLGLEKIVVLCGTDTVKDALINHA-----EEFSERAKIPVFEDIAKGHGIVFAH 117

  Fly   123 GQLWYEHRHFAMKQMRNVGYGRSQMEHHIELEAEELLGQLERTEEQPIEPVTWLAQSVLNVLWCL 187
            |:.|...|.|.:..:|:.|.|:..:|..|..|::.|:...:....:|.:....|..:..|::..:
 Frog   118 GENWKVMRRFTLSALRDFGMGKKTIEDKICEESDCLVETFKSYNGKPFDNTFILNSAAANIIVTI 182

  Fly   188 IAGKRIARQEDGTLRRLLDLMNRRSKLFDICGGLLAQ----FPWLRHVAPDRTGYNLIQQLNTEL 248
            :.|.|. ..:|..:..|:.::|:..:   |.||.:.:    :|.:....|.  .:..:.:....:
 Frog   183 LLGDRF-DYKDPKMLNLIKVVNQNMR---IGGGFMVRLYNTYPTIMRWIPG--SHQTVSKNVATI 241

  Fly   249 YGFFMDTIEEHRRQLAKDPSPAESDLIYAYLQEMKDRSAGGESSTFNETQLVMTILDFFIAGSQT 313
            :.|..:|..|||:.|..:.   :.|||.|:|.:.::.....:...:|: .|.:.:.:.|.||.:|
 Frog   242 FKFLNETFTEHRKVLDVND---QRDLIDAFLVKQQEEELSSKKFFYNQ-NLTVLVTNLFAAGMET 302

  Fly   314 TSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFHITP 378
            ||.|:...|:::...|::|:|:..::...:.:|.    |.|..|:...|.||.|.|:|||.:|.|
 Frog   303 TSTTLRWGLLLMMKYPEIQKKIQKEIDQVIGSAQ----PRLEHRKQMPYTDAVIHEIQRFANIAP 363

  Fly   379 ITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSAGKCFKDEYFMPF 443
            |..|..........||.|||...::..|.||..||.::|.|.||.||.|:||.|...|:|.|:||
 Frog   364 INIPHETTQDVTFRGYFIPKGTQVIPLLASVLRDKAYFKKPEEFYPEHFLDSEGNFVKNEAFLPF 428

  Fly   444 GMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAGESPSMVLLPGITLTPKPYKVQFVKRT 504
            ..|:|.|.|:.||:..:|.|..:::|:|:...|.|....:.....:|..|..:|:..:.|:
 Frog   429 SAGKRSCAGETLAKMELFLFFTKLLQNFTFQPPPGVEVQLTCGVALTSIPLDHKICALPRS 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	CYP15A1-like	68..498	CDD:410744	116/438 (26%)
cyp2e1.2	XP_031758885.1	cytochrome_P450	62..483	CDD:477761	116/440 (26%)