Protein Alignment Cyp305a1 and cyp2k1.8

DIOPT Version :10

• Sequence 1: NP_649151.1
• Gene: Cyp305a1 / 40161
• FlyBaseID: FBgn0036910
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: XP_012819568.1
• Gene: cyp2k1.8 / 100490476
• XenbaseID: XB-GENE-5858495
• Length: 488
• Species: Xenopus tropicalis
• Alignment Length: 515
• Identity: 146/515 - (28%)
• Similarity: 251/515 - (48%)
• Gaps: 38/515 - (7%)

  Fly     1 MSALIFLCAILIGFVIYSLI-SSARRPKNFPPGPRFVPWLGN--TLQFRKEASAVGGQHILFERW 62
            |..:..|.:::|...:|.:. ...:..:||||||:.:|.:||  .:..:|       .|:.|...
 Frog     1 MDLVSVLLSVVICIFLYKVFYGGEKESQNFPPGPKPLPIIGNFHMINMKK-------PHLTFMEL 58

  Fly    63 AKDFRSDLVGLKLGREYVVVALGHEMVKE--VQLQEVFEGRPDNFFLRLRTMGTRKGITCTDGQL 125
            ||.:.| :..::||.|.:||..|.:.||:  |...:.|..||........:.|  .|:...:|:.
 Frog    59 AKKYGS-VFSIQLGPEKLVVVCGADAVKDALVNHADEFSARPTIPVFDKTSKG--HGVFFANGEN 120

  Fly   126 WYEHRHFAMKQMRNVGYGRSQMEHHIELEAEELLGQLERTEEQPIEPVTWLAQSVLNVLWCLIAG 190
            |...|.|.:..:|:.|.|:..:|..|..|::.|:...:..:.:|.:....:..:|.|::..::..
 Frog   121 WKVMRRFTLSTLRDFGMGKKTIEDRICEESDFLMETFKSYKGKPFDNTMIMNAAVANIIVHILLN 185

  Fly   191 KRIARQEDGTLRRLLDLMNRRSKLFDICGG----LLAQFPWLRHVAPDRTGYNLIQQLNTELYGF 251
            .|...| |.||.:|::::   |:...|...    |...:|.:....|..  :..:.:...:||.|
 Frog   186 HRFDYQ-DPTLLKLINIV---SENISIAAKPIVLLYNAYPSIMEWVPGT--HKSVAENMLKLYNF 244

  Fly   252 FMDTIEEHRRQLAKDPSPAESDLIYAYLQEMKDRSAGGESST--FNETQLVMTILDFFIAGSQTT 314
            ..:|..:||.||..:.   :.|||..:|.:.::..   .|||  ||:..|.:.:.|.|.||.:||
 Frog   245 LRETFTQHRDQLDVND---QRDLIDVFLVKQQEEK---PSSTKFFNDQNLTVLLADLFGAGMETT 303

  Fly   315 SNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFHITPI 379
            |.|:...|:.:...||:|:|:..::...:.:|.    |.|..|:...|.||.|.|:||..::.|.
 Frog   304 STTLRWGLLFIMKYPDIQKKVQDEIDKVIGSAQ----PRLEHRKKMPYTDAVIHEIQRLGNLAPN 364

  Fly   380 TGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSAGKCFKDEYFMPFG 444
            .|.......| ..||.|||...::|.|.||..||:::|.|.||.||.|:||.|...|:|.|:||.
 Frog   365 VGHETTTDVT-FRGYFIPKGTQVIILLTSVLQDKDYFKKPEEFYPEHFLDSEGNFVKNEAFLPFS 428

  Fly   445 MGRRRCLGDALARACIFSFLVRIVQHFSVVLPAGESPSMVLLPGITLTPKPYKVQFVKRT 504
            .|||.|:|:.||:..:|.|..:::|:|:...|.|....:.....||..|..:::..:.|:
 Frog   429 AGRRICVGETLAKMELFLFFTKLLQNFTFQPPPGVEVDLTCADAITSKPLEHQICALPRS 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	CYP15A1-like	68..498	CDD:410744	127/437 (29%)
cyp2k1.8	XP_012819568.1	cytochrome_P450	62..482	CDD:477761	127/439 (29%)