Protein Alignment Cyp305a1 and cyp2r1

DIOPT Version :10

• Sequence 1: NP_649151.1
• Gene: Cyp305a1 / 40161
• FlyBaseID: FBgn0036910
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_001106483.2
• Gene: cyp2r1 / 100127674
• XenbaseID: XB-GENE-1013989
• Length: 501
• Species: Xenopus tropicalis
• Alignment Length: 516
• Identity: 151/516 - (29%)
• Similarity: 253/516 - (49%)
• Gaps: 56/516 - (10%)

  Fly     3 ALIFLCAILIGFVIYSLISSARRPKNFPPGPRFVPWLGNTLQFRKEASAVGGQHILFERWAKDFR 67
            ||:....::.||::..::.. |:|:.|||||..:|.:||.|....:      .|:..::.:| ..
 Frog    17 ALVAAALLIGGFLVRQIVKQ-RKPRGFPPGPPGLPLIGNILALASD------PHVYMKKQSK-IH 73

  Fly    68 SDLVGLKLGREYVVVALGHEMVKE--VQLQEVFEGRPD-NFFLRLRTMGTRKGITCTDGQLWYEH 129
            ..:..|.||....||..|::.|||  |:..:||..||. ..|.:|..||..  :....|:.|.||
 Frog    74 GQIFSLDLGGISTVVLNGYDAVKECLVRQSDVFADRPSLPLFKKLTNMGGL--LNAKYGRCWTEH 136

  Fly   130 RHFAMKQMRNVGYGRSQMEHHIELEAEELLGQLERTEEQPIEPVTWLAQSVLNVLWCLIAGKRIA 194
            |..|:...|..|..:...|..|..|....|..::..:.:.::|...:..:|.||...::.|:|.
 Frog   137 RKLAVSCFRTFGCSQKSFESKISEECLFFLDAIDSYKGKALDPKHLVTIAVSNVSNLILFGERF- 200

  Fly   195 RQEDGTLRRLLDLMNRRSKL-----------FDICGGLLAQFPWLRHVAPDRTGYNLIQQL---N 245
            |.:|.....::::.:...:|           |.:.|.|    |:.:|           |||   .
 Frog   201 RYDDNDFLHMIEIFSENIELATSAWVFLYNAFPLIGFL----PFGKH-----------QQLFRNA 250

  Fly   246 TELYGFFMDTI---EEHRRQLAKDPSPAESDLIYAYLQEMKDRSAGGESSTFNETQLVMTILDFF 307
            :|:|.|.:..|   .|:|    |..||..  .|.||:.|| :|:.....||::...|:.::.:..
 Frog   251 SEVYDFLLQIIGRFSENR----KPQSPRH--FIDAYMDEM-ERNEADPDSTYSMENLIFSVGELI 308

  Fly   308 IAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQR 372
            |||::||:|.:..|::.:|:.|::|.::..::...|.......|...||   ..|.:|.:.|:.|
 Frog   309 IAGTETTTNVLRWAMLFMALYPNIQGQVQKEIDGVVGLNRMPTFEEKSR---MPYTEAVLHEILR 370

  Fly   373 FFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSAGKCFKD 437
            :.:|.|:.........|.:.||.||:..|::.:|.|||.|:::|.||..|.||||:||||:..|.
 Frog   371 YCNIAPLGIFHATSRDTVVRGYSIPEGTTVITNLYSVHFDEKYWTDPEIFYPERFLDSAGQFTKK 435

  Fly   438 EYFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAGESPSMVLLPGITLTPKPYKV 498
            |.|:||.:|||.|||:.|||..::.|...::|.|.:..|.|..|::....|:||.|.||.:
 Frog   436 EAFVPFSLGRRHCLGEQLARMEMYLFFTALLQRFHLHFPQGFVPNLRPKLGMTLQPHPYVI 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp305a1	NP_649151.1	CYP15A1-like	68..498	CDD:410744	134/449 (30%)
cyp2r1	NP_001106483.2	CYP2R1	62..497	CDD:410754	136/464 (29%)