Protein Alignment Kap-alpha1 and imp1

DIOPT Version :10

• Sequence 1: NP_524167.1
• Gene: Kap-alpha1 / 40160
• FlyBaseID: FBgn0024889
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_596632.1
• Gene: imp1 / 2539928
• PomBaseID: SPBC1604.08C
• Length: 539
• Species: Schizosaccharomyces pombe
• Alignment Length: 557
• Identity: 267/557 - (47%)
• Similarity: 360/557 - (64%)
• Gaps: 49/557 - (8%)

  Fly     3 ASHKQRYKN-AALDSTEMRRRREEVGIQLRKNKREQQLFKRRNVVLEPATSSTSAGVESNTDNEQ 66
            :..:.|:|: ....:.|:||:|||..|::||.|||:.|.||||:   .|.......||...|..|
pombe     7 SDRRSRFKSKGVFKADELRRQREEQQIEIRKQKREESLNKRRNL---NAVLQNDIDVEEEADQSQ 68

  Fly    67 QAADMHMADSSTGGQNEEAAGSGAQPSVINEEM---IQMLFSGRENEQLEATQKFRKLLSRDPNP 128
            ...:..|.|..              |.:..:.|   |::        ||.|..||||.||::.:|
pombe    69 VQMEQQMKDEF--------------PKLTADVMSDDIEL--------QLGAVTKFRKYLSKETHP 111

  Fly   129 PIEEVIQKGIVPQFVTFLRNSANATLQFEAAWTLTNIASGTSQQTKVVIEAGAVPIFIDLLSSPH 193
            ||::||..|:|.:||.|| .|.:..|||||||.||||||||:.||::|:::||||.||.|||||.
pombe   112 PIDQVIACGVVDRFVQFL-ESEHHLLQFEAAWALTNIASGTTDQTRIVVDSGAVPRFIQLLSSPE 175

  Fly   194 DDVQEQAVWALGNIAGDSPMCRDHLLGSGILEPLLHVL-SNSDRITMIRNAVWTLSNLCRGKSPP 257
            .||:||.|||||||||||..|||::||:|:|:|||::| |::..::|:|||.||||||||||:||
pombe   176 KDVREQVVWALGNIAGDSSACRDYVLGNGVLQPLLNILQSSASDVSMLRNATWTLSNLCRGKNPP 240

  Fly   258 ADFAKISHGLPILARLLKYTDADVLSDTCWAIGYLSDGPNDKIQAVIDAGVCRRLVELLLHPQQN 322
            .:::.||..:||||:||...|.:::.|.||||.|||||||:||.|::|.|...||||||..|..|
pombe   241 PNWSTISVAVPILAKLLYSEDVEIIVDACWAISYLSDGPNEKIGAILDVGCAPRLVELLSSPSVN 305

  Fly   323 VSTAALRAVGNIVTGDDQQTQVILGYNALTCISHLLHSTAETIKKESCWTISNIAAGNREQIQAL 387
            :.|.|||:|||||||.|.|||:|:...||.....||....|.|:||:|||||||.|||.:||||:
pombe   306 IQTPALRSVGNIVTGTDAQTQIIIDCGALNAFPSLLSHQKENIRKEACWTISNITAGNTQQIQAI 370

  Fly   388 INANIFPQLMVIMQTAEFKTRKEAAWAITNATSS--GTHEQIHYLVQVGCVPPMCDFLTVVDSDI 450
            |.:|:.|.|:.::..|::||:|||.|||:||||.  |..:||.|||..|.:.|:||.|...|:.|
pombe   371 IESNLIPPLVHLLSYADYKTKKEACWAISNATSGGLGQPDQIRYLVSQGVIKPLCDMLNGSDNKI 435

  Fly   451 VQVALNALENILKAGEKFQTRP----NPYAITIEECGGLDKIEYLQAHENRDIYHKSFYIIEQYF 511
            :||||:|:|||||.||..:|..    |.||:.:||.||:|.|..||:..|.|||.|::.|||:||
pombe   436 IQVALDAIENILKVGEMDRTMDLENINQYAVYVEEAGGMDMIHDLQSSGNNDIYLKAYSIIEKYF 500

  Fly   512 GNEEEDSRVAPVA---------GTQ---QFEFDPDNM 536
            .:|:....:||..         |.|   :|:||..:|
pombe   501 SDEDAVEDLAPETENGAFTFGNGPQAQGEFKFDSQDM 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kap-alpha1	NP_524167.1	SRP1	1..543	CDD:227396	267/557 (48%)
		armadillo repeat	133..165	CDD:293788	18/31 (58%)
		armadillo repeat	173..209	CDD:293788	24/35 (69%)
		armadillo repeat	215..250	CDD:293788	19/35 (54%)
		armadillo repeat	267..292	CDD:293788	12/24 (50%)
		armadillo repeat	300..336	CDD:293788	20/35 (57%)
		armadillo repeat	342..376	CDD:293788	16/33 (48%)
		armadillo repeat	384..421	CDD:293788	19/36 (53%)
		armadillo repeat	427..461	CDD:293788	17/33 (52%)
imp1	NP_596632.1	SRP1	1..531	CDD:227396	263/549 (48%)
		armadillo repeat	115..147	CDD:293788	18/32 (56%)
		armadillo repeat	155..191	CDD:293788	24/35 (69%)
		armadillo repeat	197..233	CDD:293788	19/35 (54%)
		armadillo repeat	250..275	CDD:293788	12/24 (50%)
		armadillo repeat	285..317	CDD:293788	17/31 (55%)
		armadillo repeat	327..359	CDD:293788	14/31 (45%)
		armadillo repeat	367..403	CDD:293788	18/35 (51%)
		armadillo repeat	412..446	CDD:293788	17/33 (52%)