Protein Alignment Kap-alpha1 and F53B2.5

DIOPT Version :10

• Sequence 1: NP_524167.1
• Gene: Kap-alpha1 / 40160
• FlyBaseID: FBgn0024889
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_502400.2
• Gene: F53B2.5 / 178204
• WormBaseID: WBGene00009956
• Length: 476
• Species: Caenorhabditis elegans
• Alignment Length: 465
• Identity: 106/465 - (22%)
• Similarity: 188/465 - (40%)
• Gaps: 91/465 - (19%)

  Fly    52 SSTSAGVESNTDNEQQAA-DMHMADSSTGGQNEEAAGSGAQPSVINEEMIQMLFSGRENEQLEAT 115
            |:..|..|.|:..||.|. |:..                         :|.||.|....:...|.
 Worm     4 STKKAKQEMNSQPEQSATFDISF-------------------------IISMLESSCRIQLSTAL 43

  Fly   116 QKFRKLLSRDPNPPIEEVIQKGIVPQFVTFLRNSA-----NATLQFE----AAWTLTNIASGTSQ 171
            ..|||..:..     .::....:..||...::|..     |.||..:    |.|.:||:...:.:
 Worm    44 HFFRKAFANQ-----SDLSNIALKEQFYGRIKNGVLNALRNQTLDIDSEVNAVWIITNMCCISQE 103

  Fly   172 QTKVVIEAGAVPIFIDLLSSPHDDVQEQAVWALGNIAGDSPMCRDHLLGSGILEPLL------HV 230
            .|.:.:.:..:.|.|.|:.|.:..:..|.|||:.|||.|...|:.......:|:.|.      :.
 Worm   104 VTHLFVNSNCLDILIKLVRSQNARLSSQTVWAIANIAADCSSCKLKCRSPKLLKILARNLQTSYK 168

  Fly   231 LSNSDRITMIRNAVWTLSNLCRG--KSPPADFAKISHGLPILARLLKYTDA-DVL---SDTCWAI 289
            |.::||    |..:|.::|:..|  .:.|:..|:..  :..|:.:|..||| |.:   |...|.:
 Worm   169 LDDADR----RQLIWCVNNIFSGGRTTMPSPVARSL--ICALSAILLDTDAVDNMGCGSMILWTL 227

  Fly   290 GYLSDGPND--KIQAVIDAG-VCRRLVELLL-HPQQNVSTAALRAVGNIVTGDDQQTQVILGYNA 350
            ..|.|...|  :|..::... |...::|..: ...::.:.:.||.:|||..|:|.||.:::....
 Worm   228 ANLVDNSLDTTRIDMLLSQNYVVEHILEKFIDQTDKSCNVSCLRLIGNIAVGNDVQTDLLVDNPK 292

  Fly   351 LTCISHLLHSTAETIKKESCWTISNIAAGNREQIQALIN--ANIFPQLMVIMQTAEFKTRKEAAW 413
            ...:.::..|:.|. ..|:.|.|||:.||....:..:::  ...:..:|..:.|.:.:.|||..|
 Worm   293 FRVVMNIAMSSPEH-HSEAAWIISNVVAGAPRHVDYIMDDPDAFYEWVMAGIHTGDKRLRKECLW 356

  Fly   414 AITNATSSGTHEQIHYLVQVGCV---PPMCDFLTVVDSDIVQVALNALENILKAGEKFQT----- 470
            .|.|..::....|.:.||.:|.|   |.:.||     .|:            :..||..|
 Worm   357 IIGNLLATADEHQTYLLVSLGIVQHFPALLDF-----DDV------------RLNEKAATTATEL 404

  Fly   471 -RPNPYAITI 479
             |.:|:..|:
 Worm   405 LREHPWQYTL 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kap-alpha1	NP_524167.1	SRP1	1..543	CDD:227396	106/465 (23%)
		armadillo repeat	133..165	CDD:293788	9/40 (23%)
		armadillo repeat	173..209	CDD:293788	11/35 (31%)
		armadillo repeat	215..250	CDD:293788	7/40 (18%)
		armadillo repeat	267..292	CDD:293788	8/28 (29%)
		armadillo repeat	300..336	CDD:293788	8/37 (22%)
		armadillo repeat	342..376	CDD:293788	7/33 (21%)
		armadillo repeat	384..421	CDD:293788	8/38 (21%)
		armadillo repeat	427..461	CDD:293788	8/36 (22%)
F53B2.5	NP_502400.2	armadillo repeat	69..97	CDD:293788	7/27 (26%)
		SRP1	<87..397	CDD:227396	79/333 (24%)
		armadillo repeat	105..141	CDD:293788	11/35 (31%)
		armadillo repeat	147..184	CDD:293788	7/40 (18%)
		armadillo repeat	369..400	CDD:293788	11/47 (23%)