DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TORIP and Tor1aip2

DIOPT Version :9

Sequence 1:	NP_001262065.1	Gene:	TORIP / 40158	FlyBaseID:	FBgn0036908	Length:	301	Species:	Drosophila melanogaster
Sequence 2:	NP_001345555.1	Gene:	Tor1aip2 / 240832	MGIID:	3582695	Length:	502	Species:	Mus musculus

Alignment Length:	373	Identity:	76/373 - (20%)
Similarity:	135/373 - (36%)	Gaps:	118/373 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 NEPGALSQSKDD-VDQDHSYNRQPVQ--------SYEEGTSS---ADELEESESHDEPSIPK-PT 63
            |:|...||::|. |..:::...||:|        .:|.|..:   .|..:.|||.:||::.| |.
Mouse    30 NDPSINSQTQDTRVTPNNTAEAQPLQPTSDLKEDHHEIGARAQEHTDTGDRSESPEEPALEKPPL 94

  Fly    64 DQSRRRSISTSRPSSRQEQ--HNSINEHHNGIGIKL-------ALAGVLFGLLVVYGY------- 112
            |::...    |.|||:..:  |:..:||..|..:.|       .|.|.....|.....
Mouse    95 DKAELE----SSPSSQDTELGHHPHSEHGGGDALDLDPNCSQSDLGGRADAHLESSSVASPEGAG 155

  Fly   113 --------------------------GSSIIEEKQCDFK-------------DLRTKYP------ 132
                                      |..::.|...|.:             .||.:.|
Mouse   156 DRGEADEHLESSSAAPTEGAGDRGEAGQELLAEDSTDGQSLGHSNTGPGNQDSLRRRLPVPEAGS 220

  Fly   133 -QQQEKVWRALQKGIEGLINKKDK-----HPSVFLFLHQDPKLEKLIDEIAIEA-SMCFGGPRKL 190
             :::.::.:..|:..:..:.|.||     :.||||..        ||..:.:.: :..:..|.:.
Mouse   221 HEEETELVKEKQEVAQDTLRKTDKKSLWTYGSVFLGC--------LIVAVVLSSVNSYYSSPAQQ 277

  Fly   191 IHMK---KEHMKEYGLAIEQFKSKIN----DGKVFLIVNLNEIAPNGARALHTICDTYSPLVEDA 248
            :...   :..:.::|...|:|..:.:    .|:.||..:||...|:...   ||..|.:...::.
Mouse   278 VPQNPALEAFLAQFGQLKEKFPGQSSFLWQRGRKFLQKHLNASNPSEPA---TIIFTAAREGKET 339

  Fly   249 VIFLSLRTFN-------TTAVNNSVNLA------TDTLYDLWDQELGD 283
            :..||....|       .|||  |::.|      :||:..|.|.||.|
Mouse   340 LKCLSYHVANAYTSSQKVTAV--SIDGAERALQDSDTVKLLVDLELSD 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TORIP	NP_001262065.1	None
Tor1aip2	NP_001345555.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..211		36/184 (20%)
		LAP1C	28..492	CDD:398955	76/373 (20%)
		Interaction with TOR1A. /evidence=ECO:0000250	268..502		28/123 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR18843
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	2.060