Protein Alignment TORIP and Tor1aip2

DIOPT Version :10

• Sequence 1: NP_649149.1
• Gene: TORIP / 40158
• FlyBaseID: FBgn0036908
• Length: 301
• Species: Drosophila melanogaster
• Sequence 2: NP_766431.3
• Gene: Tor1aip2 / 240832
• MGIID: 3582695
• Length: 502
• Species: Mus musculus
• Alignment Length: 373
• Identity: 76/373 - (20%)
• Similarity: 135/373 - (36%)
• Gaps: 118/373 - (31%)

  Fly    12 NEPGALSQSKDD-VDQDHSYNRQPVQ--------SYEEGTSS---ADELEESESHDEPSIPK-PT 63
            |:|...||::|. |..:::...||:|        .:|.|..:   .|..:.|||.:||::.| |.
Mouse    30 NDPSINSQTQDTRVTPNNTAEAQPLQPTSDLKEDHHEIGARAQEHTDTGDRSESPEEPALEKPPL 94

  Fly    64 DQSRRRSISTSRPSSRQEQ--HNSINEHHNGIGIKL-------ALAGVLFGLLVVYGY------- 112
            |::...    |.|||:..:  |:..:||..|..:.|       .|.|.....|.....
Mouse    95 DKAELE----SSPSSQDTELGHHPHSEHGGGDALDLDPNCSQSDLGGRADAHLESSSVASPEGAG 155

  Fly   113 --------------------------GSSIIEEKQCDFK-------------DLRTKYP------ 132
                                      |..::.|...|.:             .||.:.|
Mouse   156 DRGEADEHLESSSAAPTEGAGDRGEAGQELLAEDSTDGQSLGHSNTGPGNQDSLRRRLPVPEAGS 220

  Fly   133 -QQQEKVWRALQKGIEGLINKKDK-----HPSVFLFLHQDPKLEKLIDEIAIEA-SMCFGGPRKL 190
             :::.::.:..|:..:..:.|.||     :.||||..        ||..:.:.: :..:..|.:.
Mouse   221 HEEETELVKEKQEVAQDTLRKTDKKSLWTYGSVFLGC--------LIVAVVLSSVNSYYSSPAQQ 277

  Fly   191 IHMK---KEHMKEYGLAIEQFKSKIN----DGKVFLIVNLNEIAPNGARALHTICDTYSPLVEDA 248
            :...   :..:.::|...|:|..:.:    .|:.||..:||...|:...   ||..|.:...::.
Mouse   278 VPQNPALEAFLAQFGQLKEKFPGQSSFLWQRGRKFLQKHLNASNPSEPA---TIIFTAAREGKET 339

  Fly   249 VIFLSLRTFN-------TTAVNNSVNLA------TDTLYDLWDQELGD 283
            :..||....|       .|||  |::.|      :||:..|.|.||.|
Mouse   340 LKCLSYHVANAYTSSQKVTAV--SIDGAERALQDSDTVKLLVDLELSD 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TORIP	NP_649149.1	None
Tor1aip2	NP_766431.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..211		36/184 (20%)
		LAP1_N	12..266	CDD:466592	48/247 (19%)
		Interaction with TOR1A. /evidence=ECO:0000250	268..502		28/123 (23%)
		LAP1_C	269..501	CDD:461691	28/122 (23%)