Protein Alignment TORIP and TOR1AIP2

DIOPT Version :10

• Sequence 1: NP_649149.1
• Gene: TORIP / 40158
• FlyBaseID: FBgn0036908
• Length: 301
• Species: Drosophila melanogaster
• Sequence 2: NP_659471.1
• Gene: TOR1AIP2 / 163590
• HGNCID: 24055
• Length: 470
• Species: Homo sapiens
• Alignment Length: 365
• Identity: 66/365 - (18%)
• Similarity: 116/365 - (31%)
• Gaps: 110/365 - (30%)

  Fly     3 NLARRPLHGNEPGALSQSKDDVDQ-DHSYNRQPV---QSYEEGTSSADE-----LEESESHDEPS 58
            ||.:.||   :|.......|.|.: |.......|   :...:||.::.|     .:|::|....|
Human   107 NLGKEPL---DPDPSHSPSDKVGRADAHLGSSSVALPKEASDGTGASQEPPTTDSQEAQSPGHSS 168

  Fly    59 IPKPTDQSRRRSISTSRPSSRQEQHNSINEHHNGIGIK---------------LALAGVLFGLLV 108
            ..:..:.:.||.:......|..:|...:.|      ||               .:...|:..:||
Human   169 AGQEGEDTLRRRLLAPEAGSHPQQTQKLEE------IKENAQDTMRQINKKGFWSYGPVILVVLV 227

  Fly   109 VYGYGSSI----------------IEEKQCDFKDLRTKYPQQQEKVWRALQKGIEGLINKKD-KH 156
            |....||:                :|.....|..|..|:|.|...:|:..:|.::..:|..: ..
Human   228 VAVVASSVNSYYSSPAQQVPKNPALEAFLAQFSQLEDKFPGQSSFLWQRGRKFLQKHLNASNPTE 292

  Fly   157 PSVFLFL--------------H-----------------------QDPKLEKLIDEIAIEASMCF 184
            |:..:|.              |                       ||....||:.::.:......
Human   293 PATIIFTAAREGRETLKCLSHHVADAYTSSQKVSPIQIDGAGRTWQDSDTVKLLVDLELSYGFEN 357

  Fly   185 GGPRKLIHMKKEHMKEY--GLAIEQFK------SKINDGKVFLIVNLNEIAPNGARALHTICDTY 241
            |....::|    |.:.:  |..:..:|      :...|..:.|.|.|.|         .|:..:.
Human   358 GQKAAVVH----HFESFPAGSTLIFYKYCDHENAAFKDVALVLTVLLEE---------ETLEASV 409

  Fly   242 SPL-VEDAVIFLSLRTFNTTAVNNSVN-LATDTLYDLWDQ 279
            .|. .|:.|..|....|..:....|.| :.:|.|..||.:
Human   410 GPRETEEKVRDLLWAKFTNSDTPTSFNHMDSDKLSGLWSR 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TORIP	NP_649149.1	None
TOR1AIP2	NP_659471.1	LAP1_N	1..222	CDD:466592	22/123 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..174		15/69 (22%)
		Interaction with TOR1A. /evidence=ECO:0000269|PubMed:23569223	236..470		38/227 (17%)
		LAP1_C	237..469	CDD:461691	38/226 (17%)