Protein Alignment Ir76a and grik5

DIOPT Version :10

• Sequence 1: NP_001097647.3
• Gene: Ir76a / 40157
• FlyBaseID: FBgn0260874
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: NP_001315085.1
• Gene: grik5 / 798791
• ZFINID: ZDB-GENE-070821-6
• Length: 1067
• Species: Danio rerio
• Alignment Length: 610
• Identity: 110/610 - (18%)
• Similarity: 200/610 - (32%)
• Gaps: 197/610 - (32%)

  Fly   147 LSGYIFQDQPNILVITSQYLN-SSTFEIKTNRFVGPRNFNKNPEPVEFYILQRFDAKGTKATWET 210
            ||..:..|..:::|...|.|| |....:|......|:.:......:.:..:..:|....:..:.:
Zfish   315 LSSALLFDAVHVVVSAVQELNRSQEIGVKPLSCTSPQIWQHGTSLMNYLRMVEYDGLTGRVEFNS 379

  Fly   211 QSAMSSKMRNL----KGREVVIGIFDYKPFMLLDYEKPPLYYDRFMNTT--DVTIDGTDIQLMLI 269
            :...::...::    :|....|||: |....||            ||:|  |:.:..|.....||
Zfish   380 KGQRTNYTLHILEKHRGGHKEIGIW-YSNNTLL------------MNSTSLDINVSETLANKSLI 431

  Fly   270 ---------------------------FC--------ELYNCTIQVDTSEPYDWGDIYLNASGYG 299
                                       ||        ::...|.::...:...:|....|.|..|
Zfish   432 ITTILENPYVMRKINYQEFEGNEQYEGFCVDMLRELSDILKFTYRIKLVDDGLYGAPEPNGSWTG 496

  Fly   300 LVGMILDRRNDYGVGGMYLWYEAYEYMDMTHFLGRSGVTCLVPAP-NRLISWTLLLRPFQFVLWM 363
            :||.:::|:.|..|....:..|..:.:|.:......|::.|.... .|...:...|.||...:|:
Zfish   497 MVGELINRKADLAVAAFTITSEREKVIDFSKPFMTLGISILYRVHIGRKPGYFSFLDPFSPAVWL 561

  Fly   364 CVMLCLLLESLALGITRR-----WEH-------------SSVAAGNS-WISSLRFGCISTLKLFV 409
            .::|..|..|..|.::.|     |.:             :....||| |.         .:..|:
Zfish   562 FMLLAYLAVSCVLFLSARLSPYEWYNPHPCLRERRDLLENQYTLGNSLWF---------PVGGFM 617

  Fly   410 NQSTNYVTSSYALRTVLVASYMIDIILTTVYSGGLAAILTLPTLEEAADSRQRLFDHKLIWTGT- 473
            .|.:..:..:.:.|.|....:...:|:.:.|:..|||.||:..:|...:|...|.|...|..||
Zfish   618 QQGSEIMPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPIESPDDLADQTNIQYGTI 682

  Fly   474 -----------------SQAW-----------ITTIDERSADPV------LL--GLMEHYRVYDA 502
                             .:.|           :.:.:|..|..|      ||  .:.|::|..:.
Zfish   683 HGGSTMTFFMNSRYQTYQRMWNYMYSKQPSVFVKSTEEGIARVVNSKYAFLLESTMNEYHRSLNC 747

  Fly   503 NLISAFSHTEQMGFVVERLQFG-------------HLGNTELIENDALKRLKLMVDDIYFAFTVA 554
            ||       .|:|.:::...:|             .|...:|.||:.|:.||
Zfish   748 NL-------TQIGGLLDTKGYGIGMPLGSPFRDELSLAVLQLQENNRLEILK------------- 792

  Fly   555 FVPRLWPHLNAYNDFILAWHSSGFDKFWE-WKIAAEYMNAHRQNRIVASEKTNLDIGPVKLGIDN 618
               |.|                     || .|...|  ..||..               .||::|
Zfish   793 ---RRW---------------------WEGGKCPKE--EDHRAK---------------GLGMEN 816

  Fly   619 FIGLILLWCFGMICSLLTFLGE-LW 642
            ..|:.::...|:|.::...:.| :|
Zfish   817 IGGIFVVLICGLIIAVFVAVMEFVW 841

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76a	NP_001097647.3	None
grik5	NP_001315085.1	PBP1_iGluR_Kainate_KA1_2	36..414	CDD:380616	19/111 (17%)
		Periplasmic_Binding_Protein_Type_2	427..797	CDD:473866	73/422 (17%)