Protein Alignment Ir76a and grin2aa

DIOPT Version :9

• Sequence 1: NP_001097647.3
• Gene: Ir76a / 40157
• FlyBaseID: FBgn0260874
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: XP_021329529.1
• Gene: grin2aa / 563297
• ZFINID: ZDB-GENE-070424-129
• Length: 1460
• Species: Danio rerio
• Alignment Length: 667
• Identity: 135/667 - (20%)
• Similarity: 229/667 - (34%)
• Gaps: 191/667 - (28%)

  Fly    64 DVYDYKIKEDEFEGKGIPYNDWTLRLTVAIERSHCETFIAFQEQIPEFARYFY-HASIYSIWRSL 127
            |.:||.::....:|.||        :|.| ..:..|.|    ..|||.....| ......:..|.
Zfish   279 DDWDYPLEARVRDGLGI--------ITTA-AAAMLEEF----GDIPEAKTSCYGQMEKTKLPPSA 330

  Fly   128 RNRFMFVYT---KEFEDKKDSYLSGYIFQDQPNILVITSQYLNSSTFEIKTNRFVGPRNFNKNPE 189
            .:::|...|   |:....:|.|      |..|.::||.   ||      |...:.....:.....
Zfish   331 LHKYMMNVTWDGKDLSFTEDGY------QVHPKLVVIV---LN------KDREWEKMGKWENQSL 380

  Fly   190 PVEFYILQRFDAKGTKATWETQSAMSSKMRNLKGREVVIGIFDYKPFMLLDYEKPPLYYDRFMNT 254
            .:::.:..||::.|...|              ....:.|...:.|||::::      ..:|...|
Zfish   381 TLKYPVWPRFNSFGDAET--------------DDNHLTIVTLEEKPFVIVE------NVERLTGT 425

  Fly   255 ------------TDVTIDGTDIQLMLI---FCELYNCTIQVDTSEPYDWGDIYLNASG------- 297
                        .|.|.:|....:...   ||......|..:....|   |:||..:|
Zfish   426 CMRNSVPCRKHIKDNTTEGGGTYIKKCCKGFCIDILKKIARNVKFTY---DLYLVTNGKHGKKIN 487

  Fly   298 ---YGLVGMILDRRNDYGVGGMYLWYEAYEYMDMTHFLGRSGVTCLVPAPNRLISWTLLLRPFQF 359
               .|:||.:::::....||.:.:..|..|.:|.:.....:|::.:|...|..:|.:..|.||..
Zfish   488 NVWNGMVGEVVNKKAVMAVGSLTINEERSEVIDFSVPFVETGISVMVSRSNGTVSPSAFLEPFSA 552

  Fly   360 VLW--MCVMLCLLLESLA---------LGITRRWEHSSVAAGNSWISS----LRFGCISTLKLFV 409
            .:|  |.||| ||:.::|         ||..|.........|.|:...    |.:|.:....:.|
Zfish   553 SVWVMMFVML-LLVTAMAVFMFEYISPLGFNRNLAQGKDPHGPSFTMGKAVWLLWGLVFNNSVPV 616

  Fly   410 NQSTNYVTSSYALRTVLVASYMIDIILTTVYSGGLAAILTLPTLEEAADSRQRLFDHKLIWTGTS 474
             |:....||.:   .|.|.::...|.|.: |:..|||.:   ..||..|....|.|.|.
Zfish   617 -QNPKGTTSKF---IVSVWAFFAVIFLAS-YTANLAAFM---IQEEFVDQVTGLSDKKF------ 667

  Fly   475 QAWITTIDERS----ADPVLLGLMEHYRVYDANLISAFSHTEQMGFVVERLQFGHLGNTELIEND 535
                     :|    :.|...|.:.:... :.|:...:....|  ::|:..|.|        .||
Zfish   668 ---------QSPYSYSPPFRFGTVPNGST-ERNIRKNYPDMHQ--YMVKYHQTG--------VND 712

  Fly   536 ALKRLKLMVDD--IYFAFTVAFVPRLWPHLNAYND-------------FILAWHSSGFDKFWEWK 585
            ||..||....|  ||.|..:.::        |..|             |....:.....|...||
Zfish   713 ALVSLKTGKLDAFIYDAAVLNYM--------AGRDEGCKLVTIGSGYIFATTGYGIALQKGSLWK 769

  Fly   586 ------------------IAAEYMNA---HRQNRIVASEKTNLDIGPVKLGIDNFIGLILLWCFG 629
                              :.|:::..   :.:|.:::|:          |.:||..|:..:....
Zfish   770 RPVDLAILAIIGDGEMEELEAQWLTGICHNEKNEVMSSQ----------LDVDNMAGVFYMLATA 824

  Fly   630 MICSLLTFLGE---LWR 643
            |..||:||:.|   .||
Zfish   825 MGLSLITFVWEHLFYWR 841

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76a	NP_001097647.3	None
grin2aa	XP_021329529.1	PBP1_iGluR_NMDA_NR2	33..389	CDD:107373	27/137 (20%)
		PBP2_iGluR_NMDA_Nr2	400..799	CDD:270436	90/450 (20%)
		NMDAR2_C	836..1460	CDD:313729	2/6 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591452
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930