Protein Alignment Ir76a and grin2bb

DIOPT Version :9

• Sequence 1: NP_001097647.3
• Gene: Ir76a / 40157
• FlyBaseID: FBgn0260874
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: NP_001121809.1
• Gene: grin2bb / 559976
• ZFINID: ZDB-GENE-061207-27
• Length: 1770
• Species: Danio rerio
• Alignment Length: 590
• Identity: 111/590 - (18%)
• Similarity: 212/590 - (35%)
• Gaps: 161/590 - (27%)

  Fly   141 DKKDSYLSGYIFQDQPNILVITSQYLNSSTFEIKTNRFVGPRNFNKNPEPVEFYILQRFDAKGTK 205
            |||.| .||     .||.::   :||.:.|||.:...| ....|..:|:.| ..:|.:.......
Zfish   400 DKKGS-KSG-----NPNEVL---RYLMNVTFEGRNLSF-SEDGFQMHPKLV-IILLNKERQYERV 453

  Fly   206 ATWETQS-AMS----------SKMRNLKGREVVIGIFDYKPFMLLDYEKPPLYYDRFMNTT---- 255
            ..||..| ||.          |.....:...:.|...:..||:::: :..||......||.
Zfish   454 GKWENGSLAMKYHVWPRFELYSDAEEREDDHLSIVTLEEAPFVIVE-DVDPLSGTCMRNTVPCRK 517

  Fly   256 -----DVTID-GTDIQLMLIFCELYNCTI--QVDTSEPYDWGDIYL----------NASGYGLVG 302
                 ::|.| |..|:..   |:.:...|  ::..|..:.: |:||          |.:..|:||
Zfish   518 QLKLQNLTGDSGIYIKRC---CKGFCIDILKKIAKSVKFTY-DLYLVTNGKHGKKINGTWNGMVG 578

  Fly   303 MILDRRNDYGVGGMYLWYEAYEYMDMTHFLGRSGVTCLVPAPNRLISWTLLLRPFQFVLWMCVML 367
            .::.:.....||.:.:..|..|.:|.:.....:|::.:|...|..:|.:..|.||...:|:.:.:
Zfish   579 EVVLKNAHMAVGSLTINEERSEVIDFSVPFIETGISVMVSRSNGTVSPSAFLEPFSADVWVMMFV 643

  Fly   368 CLLLESLA----------LGITRRWEHSSVAAGNS-------WISSLRFGCISTLKLFVNQSTNY 415
            .||:.|..          :|..|.........|.|       |   |.:|      |..|.|...
Zfish   644 MLLIVSAVAVFVFEYFSPVGYNRCLADGREPGGPSFTIGKAIW---LLWG------LVFNNSVPV 699

  Fly   416 VTSSYALRTVLVASY-MIDIILTTVYSGGLAAILTLPTLEEAADSRQRLFDHKL----------- 468
            .........::|:.: ...:|....|:..|||.:   ..||..|....|.|.|.
Zfish   700 QNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFM---IQEEYVDQVTGLSDKKFQHPNDFSPPFR 761

  Fly   469 ---IWTGTSQ-----------AWITTIDERSADPVL----LGLMEHYRVYDANLISAFSHTEQ-- 513
               :..|:::           :::|:..:::.:..|    .|.::.: :|||.:::..:..::
Zfish   762 FGTVPNGSTERNIRNNYKEMHSYMTSFHQKNVNEALHSLKSGKLDAF-IYDAAVLNYMAGRDEGC 825

  Fly   514 ------MGFVVERLQFGHLGNTELIENDA--LKRLKLMVDDIYFAFTVAFVPRLWPHLNAYNDFI 570
                  .|::     |...|....|:.|:  .:.:.|.:..::....:..:..||.....:|:
Zfish   826 KLVTIGSGYI-----FATTGYGIAIQKDSGWKRAVDLAILQLFGDGEMEELEALWLTGICHNE-- 883

  Fly   571 LAWHSSGFDKFWEWKIAAEYMNAHRQNRIVASEKTNLDIGPVKLGIDNFIGLILLWCFGMICSLL 635
                                     :|.:::|:          |.:||..|:..:....|..||:
Zfish   884 -------------------------KNEVMSSQ----------LDVDNMAGVFYMLGAAMALSLI 913

  Fly   636 TFLGE 640
            ||:.|
Zfish   914 TFIAE 918

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76a	NP_001097647.3	None
grin2bb	NP_001121809.1	PBP1_iGluR_NMDA_NR2	107..470	CDD:107373	23/80 (29%)
		ANF_receptor	138..442	CDD:279440	17/52 (33%)
		PBP2_iGluR_NMDA_Nr2	482..882	CDD:270436	74/422 (18%)
		Lig_chan	636..908	CDD:278489	48/326 (15%)
		NMDAR2_C	919..1770	CDD:287527	111/590 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591414
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930