Protein Alignment Ir76a and grik4

DIOPT Version :10

• Sequence 1: NP_001097647.3
• Gene: Ir76a / 40157
• FlyBaseID: FBgn0260874
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: XP_021322088.1
• Gene: grik4 / 556582
• ZFINID: ZDB-GENE-070821-5
• Length: 965
• Species: Danio rerio
• Alignment Length: 680
• Identity: 124/680 - (18%)
• Similarity: 222/680 - (32%)
• Gaps: 213/680 - (31%)

  Fly    66 YDYKIKEDEFEGKGIPYNDWTLRL-TVAIERSHCETFIAFQEQIPEFARYFYHASIYSIWRSLRN 129
            |.|.:...||.         .||| .:|.:|.:...|..|....|.|..:.  .|:...|:...:
Zfish   241 YTYILTSLEFS---------LLRLDDLADQRVNIVGFSVFNRTHPFFQDFV--LSLNRSWQENCD 294

  Fly   130 RFMFVYTKEFEDKKDSYLSGYIFQDQPNILVITSQYLN--------------SSTFEIKTN---- 176
            ...|..|.         ||..:..|..:.:|...|.||              |..:|..|:
Zfish   295 HAPFAGTP---------LSSALLFDAVHTVVAAVQELNRSQNVGATQLSCKSSKIWEHGTSLMNY 350

  Fly   177 -RFVGPRNFNKNPEPVEFYILQRFDAKGTKATWETQSAMSSK--MRNLKGREVVIGIFDYKPFML 238
             |.|.......:.|         |::||.::.:..:...:|:  :|.       ||.:..:..:.
Zfish   351 LRMVELEGLTGHIE---------FNSKGQRSNYALRIMQNSRDGLRQ-------IGQWHSEQGLS 399

  Fly   239 LDYEKPPLYYDRFMNTTDVTIDGTDIQLMLIFCELYNCTIQVDT--SEPY----------DWGDI 291
            ::.:.|.|      |.||.               |:|.|:.:.|  ..||          :..|.
Zfish   400 MERKLPSL------NVTDT---------------LFNTTLTITTILENPYVMLRANHQELEGNDR 443

  Fly   292 Y---------------------------------LNASGYGLVGMILDRRNDYGVGGMYLWYEAY 323
            |                                 .|.:..|:||.::.|:.|..|..:.:..|..
Zfish   444 YEGFCVDMLKELADILKFKYRIRLVGDGVYGVPGANGTWTGMVGELISRKADLAVAALTITAERE 508

  Fly   324 EYMDMTHFLGRSGVTCLVPAP-NRLISWTLLLRPFQFVLWMCVMLCLLLESLALGITRR-----W 382
            :.:|.:......|::.:.... .|...:...|.||...:|:.::|..|..|..|.:..|     |
Zfish   509 KVIDFSKPFMTLGISIMYRVHIGRRPGYFSFLDPFSPGVWLFMLLAYLAVSCVLFLVARLTPYEW 573

  Fly   383 EH-------------SSVAAGNS-WISSLRFGCISTLKLFVNQSTNYVTSSYALRTVLVASYMID 433
            .:             :..:.||| |.         .:..|:.|.:.....:.:.|.|....:...
Zfish   574 YNPHPCLKGRCSLLINQYSLGNSFWF---------PVGGFMQQGSTIAPRALSTRCVSGVWWAFT 629

  Fly   434 IILTTVYSGGLAAILTLPTLEEAADSRQRLFDHKLIWTGTSQAWIT-TIDERSADPVLLGLMEHY 497
            :|:.:.|:..|||.||:..:|...:|...|.|...|..||.....| |..:.|          .|
Zfish   630 LIIISSYTANLAAFLTVQRMEVPIESVDDLADQTAIEYGTMHGGSTMTFFQNS----------RY 684

  Fly   498 RVYDA--NLI-----SAFSHTEQMGFV-VERLQFGHLGNTELIE-----NDALKRLKLMVDDIYF 549
            :.|..  |.:     |.|..:.:.|.. |....:.:|..:.:.|     |..|.::..::|...:
Zfish   685 QTYQRMWNFMYSKQPSVFVKSTEEGIARVLNSNYAYLLESTMNEYYRQRNCNLTQIGGLLDTKGY 749

  Fly   550 AFTVAFVPRLWPHLNAYNDFILAWHSSGFDKFWEWKIAAEYMNAHRQNRIVASEKTNLDIGPVK- 613
            ...:       |..:.|.|              |:.:|  .:....:||:...::...|.|...
Zfish   750 GIGM-------PLGSVYRD--------------EFDLA--ILRLQEENRLEILKRKWWDGGKCPK 791

  Fly   614 --------LGIDNFIGLILLWCFGMICSLL 635
                    ||::|..|:.::    ::|.||
Zfish   792 EEDHRAKGLGMENIGGIFVV----LVCGLL 817

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76a	NP_001097647.3	None
grik4	XP_021322088.1	Periplasmic_Binding_Protein_type1	24..401	CDD:471960	37/195 (19%)
		PBP2_iGluR_kainate_KA1	425..785	CDD:270442	69/401 (17%)