DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir76a and CG11155

DIOPT Version :9

Sequence 1:	NP_001097647.3	Gene:	Ir76a / 40157	FlyBaseID:	FBgn0260874	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_651941.2	Gene:	CG11155 / 43822	FlyBaseID:	FBgn0039927	Length:	910	Species:	Drosophila melanogaster

Alignment Length:	457	Identity:	91/457 - (19%)
Similarity:	184/457 - (40%)	Gaps:	63/457 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   220 NLKGREVVIGIFDYKPFMLLDYEKPPLYYDRFMNTT-DVTIDGTDIQLMLIFCELYNCTIQVDTS 283
            |:....:|:...:.:|::::..:|         |.| ::..:|..|.|:...........:::..
  Fly   421 NIANITLVVMTREERPYVMVKEDK---------NLTGNLRFEGFCIDLLKAIATQVGFQYKIELV 476

  Fly   284 EPYDWGDIYL--NASGYGLVGMILDRRNDYGVGGMYLWYEAYEYMDMTHFLGRSGVTCL--VPA- 343
            ....:| :|:  ..|..|:|..:::||.|..|..|.:.|.....:|.|......|:..|  ||.
  Fly   477 PDNMYG-VYIPETNSWNGIVQELMERRADLAVASMTINYARESVIDFTKPFMNLGIGILFKVPTS 540

  Fly   344 -PNRLISWTLLLRPFQFVLWMCVMLCLLLESLALGITRR-----WEHSSVAAGNSWISSLRFGCI 402
             |.||.|:   :.|....:|:.|:...:|.|.||.:..|     |::.......:.|...:|...
  Fly   541 QPTRLFSF---MNPLAIEIWLYVLAAYILVSFALFVMARFSPYEWKNPHPCYKETDIVENQFSIS 602

  Fly   403 STL----KLFVNQSTNYVTSSYALRTVLVASYMIDIILTTVYSGGLAAILTLPTLEEAADSRQRL 463
            ::.    ..|:.|.:.....:.:.|.|....:...:|:.:.|:..|||.||:..:....:|...|
  Fly   603 NSFWFITGTFLRQGSGLNPKATSTRIVGGCWFFFCLIIISSYTANLAAFLTVERMISPIESASDL 667

  Fly   464 FDHKLIWTGTSQAWITTIDERSADPVLLGLMEH-YRVYDANLISAFSHTEQMGFVVERLQFGH-- 525
            .:...|..||.:...|....|.:.   :|:.:. :|..:....:.|..|.:.|  ::|:..|.
  Fly   668 AEQTEISYGTLEGGSTMTFFRDSK---IGIYQKMWRYMENRKTAVFVKTYEDG--IKRVMEGSYA 727

  Fly   526 --LGNTEL---IENDA-LKRLKLMVDDIYFAFTVAFVPRLWPHLNAYNDFILAWHSSG-----FD 579
              :.:|.|   ::.|. |.::..::|...:...   .|:..|..:..:..||.....|     :|
  Fly   728 FLMESTMLDYAVQRDCNLTQIGGLLDSKGYGIA---TPKGSPWRDKISLAILELQEKGIIQILYD 789

  Fly   580 KFWEWKIAAEYMNAHRQNRIVASEKTNLDIGPVKLGIDNFIGLILLWCFGMICSLLTFLGEL-WR 643
            | | ||...:..|...:::   ..|.|      .||::|..|:.::...|:..:::..:.|. |.
  Fly   790 K-W-WKNTGDVCNRDDKSK---ESKAN------ALGVENIGGVFVVLLCGLALAVVVAIFEFCWN 843

  Fly   644 GQ 645
            .:
  Fly   844 SR 845

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir76a	NP_001097647.3	None
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..410	CDD:107377
		ANF_receptor	61..393	CDD:279440
		PBP2_iGluR_Kainate	424..793	CDD:270432	78/391 (20%)
		Lig_chan	555..829	CDD:278489	57/292 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463068
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840