Protein Alignment Ir76a and Grik

DIOPT Version :9

• Sequence 1: NP_001097647.3
• Gene: Ir76a / 40157
• FlyBaseID: FBgn0260874
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: NP_001262788.1
• Gene: Grik / 42476
• FlyBaseID: FBgn0038840
• Length: 907
• Species: Drosophila melanogaster
• Alignment Length: 698
• Identity: 122/698 - (17%)
• Similarity: 231/698 - (33%)
• Gaps: 232/698 - (33%)

  Fly    52 MDWHRWANRSDQDVYDYKIKEDEFEGKGIPYNDWTLRLTVAIERSHCETFIAFQEQIPEFARYFY 116
            :|||      ..|:..|:.......|         ||| |:.:          .||:.|.|:..|
  Fly   247 LDWH------TMDLEPYQHAGTNITG---------LRL-VSPD----------SEQVQEVAKALY 285

  Fly   117 HAS--IYSIWRSLRNRFMFVYTKEFEDKKDSYLSGYIFQDQPNILVITSQYLNSSTFEIKTN--- 176
            .:.  ..::...|.|....||                  |...:|..|.:::|.....:..|
  Fly   286 ESEEPFQNVSCPLTNSMALVY------------------DGVQLLAETYKHVNFRPVALSCNDDS 332

  Fly   177 ---------RFVGPRNFNKNPEPVEFYILQRFDAKGTKATWETQ--------------------- 211
                     .::.....|....|:      |||.:|.:..::.:
  Fly   333 AWDKGYTLVNYMKSLTLNGLTGPI------RFDYEGLRTDFKLEVIELAVSGMQKIGQWSGEDGF 391

  Fly   212 --------SAMSSKMRNLKGREVVIGIFDYKPFMLLDYEKPPLY-YDRFMNTTDVTIDGTDIQLM 267
                    .::...||:|..:..|:.....:|:.:|......|. .|:|        :|..|:|:
  Fly   392 QENRPAPAHSLEPDMRSLVNKSFVVITAISEPYGMLKETSEKLEGNDQF--------EGFGIELI 448

  Fly   268 ------LIFCELYNCTIQVDTS----EPY--DWGDIYLNASGYGLVGMILDRRNDYGVGGMYLWY 320
                  |.|.  |...:|.|..    :|.  :|.         |::..|:|.|.|.|:..:.:..
  Fly   449 DELSKKLGFS--YTWRLQEDNKYGGIDPKTGEWN---------GMLREIIDSRADMGITDLTMTS 502

  Fly   321 EAYEYMDMTHFLGRSGVTCL----VPAPNRLISWTLLLRPFQFVLWMCVMLCLLLESLALGITRR 381
            |....:|.|......|:..|    :..|.:|.|:   :.||...:|:.:.|..:..|:::.:..|
  Fly   503 ERESGVDFTIPFMSLGIGILFRKPMKEPPKLFSF---MSPFSGEVWLWLGLAYMGVSISMFVLGR 564

  Fly   382 -----W--------EHSSVAAGNSWISSLRFGCISTLKLFVNQSTNYVTSSYALRTVLVASYMID 433
                 |        |.:.:....|:.:.|.|    ::...:.|.:.....:|:.|.|..:.:...
  Fly   565 LSPAEWDNPYPCIEEPTELENQFSFANCLWF----SIGALLQQGSELAPKAYSTRAVAASWWFFT 625

  Fly   434 IILTTVYSGGLAAILTLPTL----EEAAD----------------------------SRQRLFDH 466
            :||.:.|:..|||.||:.:|    .:|.|                            :.||:::
  Fly   626 LILVSSYTANLAAFLTVESLVTPINDADDLSKNKGGVNYGAKIGGATFNFFKESNYPTYQRMYE- 689

  Fly   467 KLIWTGTSQAWITTIDERSADPVLLGLMEHYRVYDANLISAFSHTEQMGFVVERLQFGHLGNTEL 531
               :...:..::|..::...|          ||.::|.......| .:.::.||
  Fly   690 ---FMRDNPQYMTNTNQEGVD----------RVENSNYAFLMEST-TIEYITER----------- 729

  Fly   532 IENDALKRLKLMVDDIYFAFTVAFVPRLWPHLNAYNDFILAWHSSGF-----DKFWEWKIAAEYM 591
              ...|.::..::|:..:...:.   :.||:.:..:..:|.....|.     .|:|:.|....
  Fly   730 --RCTLTQVGALLDEKGYGIAMR---KNWPYRDTLSQAVLEMQEQGLLTKMKTKWWQEKRGGG-- 787

  Fly   592 NAHRQNRIVASEKTNLDIGPVKLGIDNFIGLILLW----CFGMICSLL 635
                     |....:.|.|.|.|.|.|..|:.|:.    .||:..|||
  Fly   788 ---------ACSDADEDSGAVALEISNLGGVFLVMGVGSFFGIFVSLL 826

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76a	NP_001097647.3	None
Grik	NP_001262788.1	PBP1_iGluR_Kainate	37..391	CDD:107377	30/193 (16%)
		ANF_receptor	53..374	CDD:279440	30/176 (17%)
		Periplasmic_Binding_Protein_Type_2	411..781	CDD:304360	73/426 (17%)
		Lig_chan	543..816	CDD:278489	52/318 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462837
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840