DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Ir76a and Ir48b

DIOPT Version :9

Sequence 1:NP_001097647.3 Gene:Ir76a / 40157 FlyBaseID:FBgn0260874 Length:646 Species:Drosophila melanogaster
Sequence 2:NP_610697.1 Gene:Ir48b / 36254 FlyBaseID:FBgn0033648 Length:600 Species:Drosophila melanogaster


Alignment Length:670 Identity:129/670 - (19%)
Similarity:230/670 - (34%) Gaps:207/670 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    49 LIIMDWHRWANRSDQDVYDYKIKEDEFEGKGIPY-NDWTLRLTVAIERSHC-----------ETF 101
            |:|.:...:.|:||        |.:|:|.|.:.: ...:|.:..:||..:.           :.|
  Fly    37 LLISNNFLYCNQSD--------KLNEYEIKYLQHMPPISLMIFTSIESMNFTQVEYNLGADNKLF 93

  Fly   102 IAFQEQIPEFARYFYHASIYSIWRSLRNRFMF----VYTKEFEDKKDS----------YLSGYIF 152
            :....:.|.:.  |.||        |...|.|    :...|..|.|.|          :..||: 
  Fly    94 LIMGNEEPPYD--FLHA--------LNLHFQFAEYIIVIDEPVDLKKSTKWLDFVNHLWQQGYV- 147

  Fly   153 QDQPNILVITSQYLNSSTFEIKTNRFVGPRNFNK--NPEPV--EFYILQRFDAKGTKATWETQSA 213
                .:|:.||       ::.|.        ::|  .||.|  |..:.|....:|:         
  Fly   148 ----QLLIYTS-------YDEKL--------YHKIIFPETVIEETLVEQYISIRGS--------- 184

  Fly   214 MSSKMRNLKGREVVIGIFDYKPFMLLDYEKPPL-----YYDRFMNTTDVTIDGTDIQLMLIFCEL 273
                ..||.|..|.:..::..|..:|...:...     :|.||:.......:|:.:.::......
  Fly   185 ----FNNLYGYPVRVAAYNNAPRSMLYVNRWGKHIFAGFYMRFLRAFIDARNGSFVPVLTPSNSP 245

  Fly   274 YNCTIQVDTSEPYD-WGD-IYLNASGYGLVGMILDRRNDYGVGGMYLWYEAYEYMDMTHFLGRSG 336
            .|||:.: .:|..| ..| :..|.:.:.|                            ||....:.
  Fly   246 GNCTLNL-VNETVDVCADALAANPAAFSL----------------------------THGFRIAS 281

  Fly   337 VTCLVPAPNRLISWTLLLRPFQFVLWMCVMLCLLLESLALGITRRWEHSSVAAGNSWISSLRFGC 401
            ...||.....|.|:..|..|||:.:|.|:::.:||               |....|:|..||.|.
  Fly   282 ANVLVTHAKPLHSYRYLTAPFQWSVWACLVIYVLL---------------VVNFLSFIGWLRSGK 331

  Fly   402 ISTLKLFVNQSTNYVTSSYALRTV--------LVASYMIDIILTTVYSGGLAAILTLPTLEEAAD 458
            ....|..:...::.:.|.:.|:.:        ....::...:.:|.|.|.|.::|.....|:..|
  Fly   332 WEFSKYLLEVFSSLLFSGFYLKEIRGRERYILFGVLFIAGFVYSTEYLGLLKSMLISEVFEKQID 396

  Fly   459 SRQRLFDHKLIWTGTSQAWITTIDERSADPVLLGLMEHYRVYDANLISAFSHTEQMGFVVERLQF 523
            :.:.|.:..          ||.:    .||           ||..|.:.::..|.:..::|.:.|
  Fly   397 TFEALVESN----------ITLM----VDP-----------YDKILFAKYNMPEILSPIMELVSF 436

  Fly   524 GH-LGNTELIEND------------------ALKRLKLMVDDIYFAFTVAFVP--RLW---PHLN 564
            .. |.:....:.|                  .||..||:...|.|:|....:|  :.|   .||.
  Fly   437 ETLLKHRNRFDQDYAYILFSDRMALYDYAQQFLKHPKLLRIPIDFSFLYTGIPMRKRWFLKHHLG 501

  Fly   565 AYNDFILAWH---SSGFDKFWEWKIAAEY-MNAHRQNRIVASEKTNLDIGPVKLGIDNFIGLILL 625
            .      ||:   .||..:    |:|.:. ..|.|...:......:::..|  |.:|.|:...:.
  Fly   502 R------AWYWAFESGLTR----KLALDADFEAVRVGYLSFLITEHVEAQP--LNVDYFVMPAIA 554

  Fly   626 WCFGMICSLLTFLGEL--WR 643
            ...|.|.:||:|:.|:  ||
  Fly   555 LAIGYILALLSFVIEMTAWR 574



Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR42643
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
22.010

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