Protein Alignment Ir76a and Ir25a

DIOPT Version :10

• Sequence 1: NP_001097647.3
• Gene: Ir76a / 40157
• FlyBaseID: FBgn0260874
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: NP_001260049.1
• Gene: Ir25a / 33683
• FlyBaseID: FBgn0031634
• Length: 947
• Species: Drosophila melanogaster
• Alignment Length: 615
• Identity: 113/615 - (18%)
• Similarity: 201/615 - (32%)
• Gaps: 201/615 - (32%)

  Fly    62 DQDVYDYKIKEDEFEGKGIPYNDWTLRLTVAIERSHCETFIA------FQEQIP-----EFARYF 115
            |..|.|:|.|.                |...|:..|..|.||      .:|||.     :...:|
  Fly   187 DSFVMDHKYKS----------------LLQNIQTRHVITAIAKDGKREREEQIEKLRNLDINNFF 235

  Fly   116 YHASIYSI-----------------WRSLRNR------------FMFV----YTKEFEDKKDSYL 147
            ...::.||                 |.::...            .||:    || ::.|:.....
  Fly   236 ILGTLQSIRMVLESVKPAYFERNFAWHAITQNEGEISSQRDNATIMFMKPMAYT-QYRDRLGLLR 299

  Fly   148 SGYIFQDQPNI-------LVITS-----------------QYLNSSTFE--IKTNRFVGPRN-FN 185
            :.|...::|.:       |.:.|                 :|||...|:  ....|.:..|: |.
  Fly   300 TTYNLNEEPQLSSAFYFDLALRSFLTIKEMLQSGAWPKDMEYLNCDDFQGGNTPQRNLDLRDYFT 364

  Fly   186 KNPEPVEF---------------YILQRFD------------AKGTKATWETQSAMSS------- 216
            |..||..:               :...:|:            :..:|:..:..|.::|
  Fly   365 KITEPTSYGTFDLVTQSTQPFNGHSFMKFEMDINVLQIRGGSSVNSKSIGKWISGLNSELIVKDE 429

  Fly   217 -KMRNLKGREVVIGIFD--YKPFMLLDYEKPPLYYDRFMNTTDVTIDGTDIQLMLIFCELYNCTI 278
             :|:||.. :.|..||.  ..||::.|...|..|            .|..|.|:.....:.:...
  Fly   430 EQMKNLTA-DTVYRIFTVVQAPFIMRDETAPKGY------------KGYCIDLINEIAAIVHFDY 481

  Fly   279 QVDTSEPYDWGDIYLNASGYGLVGMILDRRNDYGVGGMYLWYEAYEYMDMT-HFLGRSGVTCLVP 342
            .:...|...:|::..|....|:|..::|::.|.|:|.|.:..|....:|.| .:....|:|.::.
  Fly   482 TIQEVEDGKFGNMDENGQWNGIVKKLMDKQADIGLGSMSVMAEREIVIDFTVPYYDLVGITIMMQ 546

  Fly   343 APNRLISWTLLLRPFQFVLWMCVMLCLLLESLALGITRRWEHSSVAAGNS--------------- 392
            .|:...|....|...:..:|:|::......|..:.|..||...|......
  Fly   547 RPSSPSSLFKFLTVLETNVWLCILAAYFFTSFLMWIFDRWSPYSYQNNREKYKDDEEKREFNLKE 611

  Fly   393 --WISSLRFGCISTLKLFVNQSTNYVTSSYALRTVLVASYMIDIILTTVYSGGLAAILTLPTLEE 455
              |.      |:::|   ..|.......:.:.|.|....::...|:...|:..|||.||:..|:.
  Fly   612 CLWF------CMTSL---TPQGGGEAPKNLSGRLVAATWWLFGFIIIASYTANLAAFLTVSRLDT 667

  Fly   456 AADSRQRLF-DHKLIWTGTSQAWITTIDERSADPVLLGLMEHYRVYDANLISAFSHTEQMGFVVE 519
            ..:|...|. .:|:::...:.:...|..||                       .|:.|||.:.:.
  Fly   668 PVESLDDLAKQYKILYAPLNGSSAMTYFER-----------------------MSNIEQMFYEIW 709

  Fly   520 RLQFGHLGNTELIEND---ALKRLKLMVDD 546
            :         :|..||   |::|.||.|.|
  Fly   710 K---------DLSLNDSLTAVERSKLAVWD 730

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76a	NP_001097647.3	None
Ir25a	NP_001260049.1	PBP1_iGluR_AMPA_Like	37..418	CDD:380606	39/247 (16%)
		PBP2_iGluR_putative	438..836	CDD:270435	69/346 (20%)