Protein Alignment Ir76a and Ir67c

DIOPT Version :10

• Sequence 1: NP_001097647.3
• Gene: Ir76a / 40157
• FlyBaseID: FBgn0260874
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: NP_729609.1
• Gene: Ir67c / 317838
• FlyBaseID: FBgn0052058
• Length: 573
• Species: Drosophila melanogaster
• Alignment Length: 647
• Identity: 119/647 - (18%)
• Similarity: 213/647 - (32%)
• Gaps: 204/647 - (31%)

  Fly    83 NDWTLRLTVAIERSHCETFIAFQ----------EQIPEFARYFYHASIYSIWR-SLRNR------ 130
            :|..|:|.:.::.:..|..|..:          :::....|:..|:.|.:.:: |.|||
  Fly    31 HDQQLQLNIYLDCNDVELQIGQEVSNLFVNSTADKMKILGRFSSHSLIIACFKDSTRNRTLNGVK 95

  Fly   131 ----------FMFVYTKEFEDKKDSYLSGYIFQDQPN--ILVITSQYLNSSTF------EIKTNR 177
                      .:||.        ||.:..|..|...:  |.|:...::|.|.:      :::.::
  Fly    96 ELLWGLQYLPILFVV--------DSNMDFYFQQALRHGFIHVLALNFMNGSLYTYKPYPKVEVHQ 152

  Fly   178 FVGPRNFNKNPEPVEFYILQRFDAKGTKATWETQSAMSSKMRNLKGREVVIGIFDYKPFMLLDYE 242
            ....:.|.|..:      |:....:..:.|.||.:....:.||..|:.|..|
  Fly   153 IKDMQKFYKLTK------LRNLQGQAVRTTVETMTPRCFRYRNRHGQLVYAG------------- 198

  Fly   243 KPPLYYDRFMNTTDVTIDGTDIQLMLIFCELYNCTIQVDTSEPYDWGDIYLNASGYGLVGMILDR 307
                |..|.:.....|.:||:..:.          ..||| .||..|...|......::..|:..
  Fly   199 ----YMYRMVKEFISTYNGTEEHVF----------GNVDT-VPYKEGLAALKNGEIDMMPRIIHA 248

  Fly   308 RNDYGVGGMYLWYEAYEYMDMTHFLGRSGVTCLVPAPNRLISWTLLLRPFQFVLWMCVMLCLLLE 372
            ..         ||    |...:|.|.......:||....|......::||:..:|:.:|:..:..
  Fly   249 LE---------WY----YFYRSHILYNIKTYIMVPWAEPLPKSLYFIQPFRGTVWITIMVSFVYA 300

  Fly   373 SLALGITRRWEHSSVAAGNSWI-------SSLRFGCISTLKLF----------VNQSTNYVTSSY 420
            |:.:     |          ||       |||....:..|:|.          .|..|:.|.|
  Fly   301 SIVI-----W----------WIRYRQQGNSSLTQSFMDVLQLLFQLPLSKIWHFNMGTHQVVS-- 348

  Fly   421 ALRTVLVASYMIDIILTTVYSGGLAAILT-------LPTLEEAADSRQRL----FDHKLIWTGTS 474
                 .:..::...:||.:|:..|::.||       :.|.::....::.|    ||.:::...|.
  Fly   349 -----FIVLFVFGFMLTNLYTAQLSSYLTTGLFKSQINTFDDLFREKRTLLVESFDAEVLHNMTK 408

  Fly   475 Q----------AWITTIDERSADPVLLGLMEHYRVYDANLISAFSHTEQMGFVVERLQFGHLGNT 529
            :          ..||:|:|.......|.....|..|:                 :|:.| .|...
  Fly   409 EKIIQKEFESIILITSIEEVFKHRKSLNTSYAYEAYE-----------------DRIAF-ELSQQ 455

  Fly   530 ELIENDALKRLKLMVDD--IYFAFTVAFVPRLWPHLNAYNDFILAWHSSGF------DKFWEWKI 586
            ..:.....|.||.:.|.  ::.|.....     |::..:|:::.....||.      |.|.|...
  Fly   456 RYLRVPIFKILKEVYDQRPVFVALRHGL-----PYVELFNNYLRRIFESGIWIKLQEDSFLEGIA 515

  Fly   587 AAEYMNAHRQNRIVASEKTNLDIGPVKLGIDN---FIGLILL---WCFGMICSLLTFLGELW 642
            :.|......::|            .:|: .|.   |...|||   ||...|...|    |||
  Fly   516 SGEISFRKSKSR------------EIKI-FDKDFYFFAYILLGMGWCVSTIALFL----ELW 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76a	NP_001097647.3	None
Ir67c	NP_729609.1	7tm_GPCRs	<279..357	CDD:475119	17/99 (17%)
		TM helix 5	279..306	CDD:320097	6/41 (15%)