DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir76a and Ir7c

DIOPT Version :9

Sequence 1:	NP_001097647.3	Gene:	Ir76a / 40157	FlyBaseID:	FBgn0260874	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_001245572.1	Gene:	Ir7c / 31692	FlyBaseID:	FBgn0029966	Length:	625	Species:	Drosophila melanogaster

Alignment Length:	564	Identity:	125/564 - (22%)
Similarity:	212/564 - (37%)	Gaps:	127/564 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 RNRFMFVYTKEFEDKKDSYLSGYIFQDQPNILVITSQYL--NSSTFEIKTNRFVGPRNFNKNPEP 190
            ||.|..|.....||:....|. .:|:...|:.|:.....  ...|..:.|....||.:. ::..|
  Fly   119 RNGFFLVIYTGLEDQPMESLK-IMFRRLLNMYVLNVNVFLQRDGTVHLYTYYPYGPHHC-QSSLP 181

  Fly   191 VEFYILQRFDAKGTKATWETQSAMSSKMRNLKGREVVIGIFDYKPFMLL-DYEKPPLYYDRFMNT 254
            |.:...|.. |........|:.....|:.|:.|.|:|:..|:::|:::: |..|.|
  Fly   182 VYYTAFQDL-AAPANGFGLTKPLFPRKLTNMHGCEMVVATFEHRPYVIIEDDPKTP--------- 236

  Fly   255 TDVTIDGTDIQLMLIFCELYNCTIQVDTSEPYDWGDIYLNASGYGLVGMILDRRNDYGVGGMYLW 319
            ...:|.|.:..:.....|..|.||::...:..:.|:|..:.:..|::.|::|       |.:.|.
  Fly   237 GGRSIHGIEGLIFRSLAERMNFTIKLVEQKDKNRGEILPDGNFTGILKMMVD-------GEVNLT 294

  Fly   320 YEAYEY-----------MDMTHFLGRSGVTCLVPAPNRLISWTLLLRPFQFVLWMC--------- 364
            :..:.|           ...|.|    .:..:||:...:.....|.|||::::|.|
  Fly   295 FVCFMYSKARSDLMLPSTSYTSF----PIVLVVPSGGSISPMGRLTRPFRYIIWSCILVSLIFGF 355

  Fly   365 VMLCLL-------LESLALGITRRWEHSSVAAGNSWISSLRFGCISTLKLFVNQSTNYVTSSYAL 422
            |::|||       |.:|.||...|.....:     |.|.|     ..|.|: |...|:.
  Fly   356 VLICLLKITALPGLRNLVLGRRNRLPFMGM-----WASLL-----GGLALY-NPQRNFA------ 403

  Fly   423 RTVLVASYMIDIILTTVYSGGLAAIL-------TLPTLEE--AADSRQRLFDHKLIWTGTSQAWI 478
            |.:||...:..:||...|:|.|..:|       .:.:|.|  |.|...|:...           :
  Fly   404 RYILVMWLLQTLILRAAYTGQLYLLLQDVEMRSPIKSLSEVLAKDYEFRILPA-----------L 457

  Fly   479 TTIDERSADP----VLLGLMEH-YRVYDANLISAFSHTEQMGFVVERLQFGHLGNTELIENDALK 538
            .||.:.|...    .:|.|.|. ||:.|         .:..|..|..|| ..:...:.......:
  Fly   458 RTIFKDSMPTTNFHAVLSLEESLYRLRD---------EDDPGITVALLQ-PTVNQFDFRSGPNKR 512

  Fly   539 RLKLMVDDIYFAFTVAFVPRLWPHLNAY-----NDFILAWHSSGFDKFWEWKIAAEYMNAHRQNR 598
            .|.::.|.:..| .:.|..|  ||  :|     :..|:|..|||        |.|.|...:....
  Fly   513 HLTVLPDPLMTA-PLTFYMR--PH--SYFKRRIDRLIMAMMSSG--------IVARYRKMYMDRI 564

  Fly   599 IVASEKTNLDIGPVKLGIDNFIGLILLWCFGM-ICSLLTFLGEL 641
            ...|::.||:  |..|.|....| |.:.|.|: :.:|:.|:.|:
  Fly   565 KRVSKRRNLE--PKPLSIWRLSG-IFVCCAGLYLVALIVFILEI 605

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir76a	NP_001097647.3	None
Ir7c	NP_001245572.1	Lig_chan-Glu_bd	225..287	CDD:214911	14/70 (20%)
Ir7c	NP_001245572.1	Lig_chan	343..593	CDD:278489	70/303 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440215
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42643
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940