Protein Alignment Ir76a and Nmdar2

DIOPT Version :9

• Sequence 1: NP_001097647.3
• Gene: Ir76a / 40157
• FlyBaseID: FBgn0260874
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: NP_001014714.1
• Gene: Nmdar2 / 31107
• FlyBaseID: FBgn0053513
• Length: 1083
• Species: Drosophila melanogaster
• Alignment Length: 616
• Identity: 118/616 - (19%)
• Similarity: 213/616 - (34%)
• Gaps: 140/616 - (22%)

  Fly   114 YFYHASIYSIWRSLRNRFMFVYTKEFEDK-KDSYLSGYIF------------QDQPNILVITSQY 165
            |.|....|....:.|:|.:...:...||: :..:.:|.||            .::|||.......
  Fly   381 YSYGVEAYLTDPANRDRRLTTQSLSCEDEGRGRWDNGEIFFKYLRNVSIEGDLNKPNIEFTADGD 445

  Fly   166 LNSSTFEIKTNRFVGPRNFNKNPEPVEFYILQRFDAKGTKATWETQSAMSSKMRNLKGREVV--- 227
            |.|:..:|...|   |...|||         ..::..|...:||||        .|..|::.
  Fly   446 LRSAELKIMNLR---PSANNKN---------LVWEEIGVWKSWETQ--------KLDIRDIAWPG 490

  Fly   228 ----------------IGIFDYKPFMLLDYEKP---PLYYDRFM---------NTTDVTI----- 259
                            |...:..|::.|....|   ....||.:         ...|:.:
  Fly   491 NSHAPPQGVPEKFHLKITFLEEAPYINLSPADPVSGKCLMDRGVLCRVAADHEMAADIDVGQAHR 555

  Fly   260 --------DGTDIQLMLIFCELYNCTIQVDTSEPYDWGDIYLNASGYGLVGMILDRRNDYGVGGM 316
                    .|..|.|:..|.|....|.::...|...||.:. |....||:..:::|:.|..:..:
  Fly   556 NESFYQCCSGFCIDLLEKFAEELGFTYELVRVEDGKWGTLE-NGKWNGLIADLVNRKTDMVLTSL 619

  Fly   317 YLWYEAYEYMDMTHFLGRSGVTCLVPAPNRLISWTLLLRPFQFVLWMCVMLCLLLESLALGITRR 381
            .:..|....:|.:.....:|:..:|.....:||.|..|.||....||.|.:..:..:..:.....
  Fly   620 MINTEREAVVDFSEPFMETGIAIVVAKRTGIISPTAFLEPFDTASWMLVGIVAIQAATFMIFLFE 684

  Fly   382 WEHSS-----VAAGNSWISSLRFGCISTLKL---FVNQSTNYVTS--SYALRTVLVASYMIDIIL 436
            |...|     :...|:.::..||....|..|   .:.|:..:|.|  .:..|.:.....:..::.
  Fly   685 WLSPSGYDMKLYLQNTNVTPYRFSLFRTYWLVWAVLFQAAVHVDSPRGFTSRFMTNVWALFAVVF 749

  Fly   437 TTVYSGGLAAILTLPTLEE------AADSR-QRLFDHKLIWTGTSQAWITTIDERSADPVL---L 491
            ..:|:..|||.:.  |.||      ..||| ...|.||..:.      ..||.....|..:   .
  Fly   750 LAIYTANLAAFMI--TREEFHEFSGLNDSRLVHPFSHKPSFK------FGTIPYSHTDSTIHKYF 806

  Fly   492 GLMEHY-RVYD----ANLISAFSHTEQMGFVVERLQFGHLGNTELIENDALKRLKLMVDDIYFAF 551
            .:|.:| |.|:    |:.::|..:.....|:.:.....:     |:..|  :..:||....::|.
  Fly   807 NVMHNYMRQYNKTSVADGVAAVLNGNLDSFIYDGTVLDY-----LVAQD--EDCRLMTVGSWYAM 864

  Fly   552 T---VAFVPRLWPHLNAYNDFILAWHSSG----FDKFWEWKIAAEYMNAHRQNRIVASEKTNLDI 609
            |   :|| .|...::..:|..:|.:.::|    ..::|...........|:.:.
  Fly   865 TGYGLAF-SRNSKYVQMFNKRLLEFRANGDLERLRRYWMTGTCRPGKQEHKSSD----------- 917

  Fly   610 GPVKLGIDNFIGLILLWCFGMICSLLTFLGE 640
               .|.::.|:...||...|::.:.|..|.|
  Fly   918 ---PLALEQFLSAFLLLMAGILLAALLLLLE 945

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76a	NP_001097647.3	None
Nmdar2	NP_001014714.1	PBP1_iGluR_NMDA_NR2	99..490	CDD:107373	28/128 (22%)
		PBP2_iGluR_NMDA_Nr2	502..908	CDD:270436	81/422 (19%)
		Lig_chan	665..928	CDD:278489	53/292 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463023
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840