Protein Alignment Ir76a and GRIA3

DIOPT Version :9

• Sequence 1: NP_001097647.3
• Gene: Ir76a / 40157
• FlyBaseID: FBgn0260874
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: NP_000819.4
• Gene: GRIA3 / 2892
• HGNCID: 4573
• Length: 894
• Species: Homo sapiens
• Alignment Length: 197
• Identity: 43/197 - (21%)
• Similarity: 79/197 - (40%)
• Gaps: 29/197 - (14%)

  Fly   299 GLVGMILDRRNDYGVGGMYLWYEAYEYMDMTHFLGRSGVTCLVPAPNR----LISWTLLLRPFQF 359
            |:||.::..|.|..|..:.:.....|.:|.:......|::.::..|.:    :.|:   |.|..:
Human   492 GMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSF---LDPLAY 553

  Fly   360 VLWMCVMLCLLLESLALGITRR-----WE-----------HSSVAAGNSW--ISSLRFGCISTLK 406
            .:|||::...:..|:.|.:..|     |.           .|.....|.:  .:||.|    :|.
Human   554 EIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWF----SLG 614

  Fly   407 LFVNQSTNYVTSSYALRTVLVASYMIDIILTTVYSGGLAAILTLPTLEEAADSRQRLFDHKLIWT 471
            .|:.|..:....|.:.|.|....:...:|:.:.|:..|||.||:..:....:|.:.|.....|..
Human   615 AFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAY 679

  Fly   472 GT 473
            ||
Human   680 GT 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76a	NP_001097647.3	None
GRIA3	NP_000819.4	PBP1_iGluR_AMPA_GluR3	35..409	CDD:380610
		PBP2_iGluR_AMPA	422..805	CDD:270433	43/197 (22%)
		Glutamate binding. /evidence=ECO:0000250	508..510		0/1 (0%)
		Glutamate binding. /evidence=ECO:0000250	686..687

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156225
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840