Protein Alignment Ir76a and Grik5

DIOPT Version :9

• Sequence 1: NP_001097647.3
• Gene: Ir76a / 40157
• FlyBaseID: FBgn0260874
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: XP_006228444.1
• Gene: Grik5 / 24407
• RGDID: 2735
• Length: 980
• Species: Rattus norvegicus
• Alignment Length: 683
• Identity: 122/683 - (17%)
• Similarity: 206/683 - (30%)
• Gaps: 256/683 - (37%)

  Fly    40 RLETVHPMPLIIMDWHRWANRSDQDVYDYKIKED------EFEGKGIPYNDWTLRLTVAIERSHC 98
            |.:.:...||.....:.|.:.:....|...::.|      ||..||...| :|||:.....:.|.
  Rat   323 RSQEIGVKPLACTSANIWPHGTSLMNYLRMVEYDGLTGRVEFNSKGQRTN-YTLRILEKSRQGHR 386

  Fly    99 ETFIAFQEQIPEFARYFYHASIYSIWRSLRNRFMFVYTKEFEDKKDSYLSGYIFQDQPNILVITS 163
            |                     ..:|.|.|...|...|.:                     :..|
  Rat   387 E---------------------IGVWYSNRTLAMNATTLD---------------------INLS 409

  Fly   164 QYLNSSTFEIKTNRFVGPRNFNKNPEPVEFYILQR--FDAKGTKATWETQSAMSSKMRNLKGREV 226
            |.|.:.|..:.|        ..:||     |:::|  |.|                   |.|.|
  Rat   410 QTLANKTLVVTT--------ILENP-----YVMRRPNFQA-------------------LSGNE- 441

  Fly   227 VIGIFDYKPFMLLDYEKPPLYYDRFMNTTDVTIDGTDIQLMLIFCELYNCTIQVDTSEPYDWGDI 291
                                   ||        :|..:.::....||.....::...|...:|..
  Rat   442 -----------------------RF--------EGFCVDMLRELAELLRFRYRLRLVEDGLYGAP 475

  Fly   292 YLNASGYGLVGMILDRRN-DYGVGGMYLWYEAYEYMDMTHFLGRSGVTCLVPA-PNRLISWTLLL 354
            ..|.|..|:||.:::|:. |..|....:..|..:.:|.:......|::.|... ..|...:...|
  Rat   476 EPNGSWTGMVGELINRQKADLAVAAFTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGYFSFL 540

  Fly   355 RPFQFVLWMCVMLCLLLESLALGITRR-----W--EHSSVAA-----------GNS-WISSLRFG 400
            .||...:|:.::|..|..|..|.:..|     |  .|..:.|           ||| |.
  Rat   541 DPFSPAVWLFMLLAYLAVSCVLFLAARLSPYEWYNPHPCLRARPHILENQYTLGNSLWF------ 599

  Fly   401 CISTLKLFVNQSTNYVTSSYALRTVLVASYMIDIILTTVYSGGLAAILTLPTLEEAADSRQRLFD 465
               .:..|:.|.:..:..:.:.|.|....:...:|:.:.|:..|||.||:..:|...:|...|.|
  Rat   600 ---PVGGFMQQGSEIMPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPVESADDLAD 661

  Fly   466 HKLIWTGTSQAWIT-------------------------------------TIDERSADPVLLGL 493
            ...|..||..|..|                                     .::.|.|..:...:
  Rat   662 QTNIEYGTIHAGSTMTFFQNSRYQTYQRMWNYMQSKQPSVFVKSTEEGIARVLNSRYAFLLESTM 726

  Fly   494 MEHYRVYDANLISAFSHTEQMGFVVERLQFG---HLGN----------TELIENDALKRLKLMVD 545
            .|::|..:.||       .|:|.:::...:|   .||:          .:|.||:.|:.||
  Rat   727 NEYHRRLNCNL-------TQIGGLLDTKGYGIGMPLGSPFRDEITLAILQLQENNRLEILK---- 780

  Fly   546 DIYFAFTVAFVPRLWPHLNAYNDFILAWHSSGFDKFWEWKIAAEYMNAHRQNRIVASEKTNLDIG 610
                        |.|            |......|          ...||..
  Rat   781 ------------RKW------------WEGGRCPK----------EEDHRAK------------- 798

  Fly   611 PVKLGIDNFIGLILLWCFGMICSLLTFLGE-LW 642
              .||::|..|:.::...|:|.::...:.| :|
  Rat   799 --GLGMENIGGIFVVLICGLIIAVFVAVMEFIW 829

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76a	NP_001097647.3	None
Grik5	XP_006228444.1	PBP1_iGluR_Kainate_KA1_2	23..401	CDD:380616	20/99 (20%)
		Periplasmic_Binding_Protein_Type_2	414..785	CDD:389745	86/478 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350156
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840