Protein Alignment Ir76a and Grik4

DIOPT Version :9

• Sequence 1: NP_001097647.3
• Gene: Ir76a / 40157
• FlyBaseID: FBgn0260874
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: NP_036704.1
• Gene: Grik4 / 24406
• RGDID: 2734
• Length: 956
• Species: Rattus norvegicus
• Alignment Length: 616
• Identity: 116/616 - (18%)
• Similarity: 210/616 - (34%)
• Gaps: 189/616 - (30%)

  Fly   119 SIYSIWRSLR--NRFMFVYTKEFEDKKDSYLSGYIFQDQPNILVITSQYLNSSTFEIKTNRFVGP 181
            ::|::..:::  ||     ::|...|..|..|..|:|...:::    .||..    ::.....|.
  Rat   311 AVYAVVTAVQELNR-----SQEIGVKPLSCGSAQIWQHGTSLM----NYLRM----VELEGLTGH 362

  Fly   182 RNFNKNPEPVEFYI-LQRFDAKGTK--ATWETQSAMSSKMR--------NLKGREVVIGIFDYKP 235
            ..||...:...:.: :.:|...|.:  ..|.....:|...|        :|....:|:......|
  Rat   363 IEFNSKGQRSNYALKILQFTRNGFRQIGQWHVAEGLSMDSRLYASNISDSLFNTTLVVTTILENP 427

  Fly   236 FMLL-----DYEKPPLYYDRFMNTTDVTIDGTDIQLMLIFCEL--YNCTIQVDTSEPYDWGDIYL 293
            :::|     |.|.    .||:        :|..:.::....|:  :|..|::.....|  |....
  Rat   428 YLMLKGNHQDMEG----NDRY--------EGFCVDMLKELAEILRFNYKIRLVGDGVY--GVPEA 478

  Fly   294 NASGYGLVGMILDRRNDYGVGGMYLWYEAYEYMDMTHFLGRSGVTCLVPA-PNRLISWTLLLRPF 357
            |.:..|:||.::.|:.|..|.|:.:..|..:.:|.:......|::.|... ..|...:...|.||
  Rat   479 NGTWTGMVGELIARKADLAVAGLTITAEREKVIDFSKPFMTLGISILYRVHMGRRPGYFSFLDPF 543

  Fly   358 QFVLWMCVMLCLLLESLALGITRR-----W--EH-----------SSVAAGNS-WISSLRFGCIS 403
            ...:|:.::|..|..|..|.:..|     |  .|           :..:.||| |.
  Rat   544 SPGVWLFMLLAYLAVSCVLFLVARLTPYEWYSPHPCAQGRCNLLVNQYSLGNSLWF--------- 599

  Fly   404 TLKLFVNQSTNYVTSSYALRTVLVASYMIDIILTTVYSGGLAAILTLPTLEEAADSRQRLFDHKL 468
            .:..|:.|.:.....:.:.|.|....:...:|:.:.|:..|||.||:..:|...:|...|.|...
  Rat   600 PVGGFMQQGSTIAPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPIESVDDLADQTA 664

  Fly   469 IWTGT------------------SQAW-----------ITTIDE------RSADPVLL--GLMEH 496
            |..||                  .:.|           :.:.:|      .|....||  .:.|:
  Rat   665 IEYGTIHGGSSMTFFQNSRYQTYQRMWNYMYSKQPSVFVKSTEEGIARVLNSNYAFLLESTMNEY 729

  Fly   497 YRVYDANLISAFSHTEQMGFVVERLQFG-------------HLGNTELIENDALKRLKLMVDDIY 548
            ||..:.||       .|:|.:::...:|             .|...:|.||:.|:.||
  Rat   730 YRQRNCNL-------TQIGGLLDTKGYGIGMPVGSVFRDEFDLAILQLQENNRLEILK------- 780

  Fly   549 FAFTVAFVPRLWPHLNAYNDFILAWHSSGFDKFWE-WKIAAEYMNAHRQNRIVASEKTNLDIGPV 612
                     |.|                     || .|...|  ..||..
  Rat   781 ---------RKW---------------------WEGGKCPKE--EDHRAK--------------- 798

  Fly   613 KLGIDNFIGLILLWCFGMICSL-LTFLGELW 642
            .||::|..|:.::...|:|.:: :..|..||
  Rat   799 GLGMENIGGIFVVLICGLIVAIFMAMLEFLW 829

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76a	NP_001097647.3	None
Grik4	NP_036704.1	Periplasmic_Binding_Protein_type1	24..402	CDD:415822	18/103 (17%)
		PBP2_iGluR_kainate_KA1	415..785	CDD:270442	81/436 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	931..956

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349681
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840