Protein Alignment Ir76a and gria2a

DIOPT Version :9

• Sequence 1: NP_001097647.3
• Gene: Ir76a / 40157
• FlyBaseID: FBgn0260874
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: XP_005170953.1
• Gene: gria2a / 170450
• ZFINID: ZDB-GENE-020125-3
• Length: 893
• Species: Danio rerio
• Alignment Length: 652
• Identity: 128/652 - (19%)
• Similarity: 217/652 - (33%)
• Gaps: 147/652 - (22%)

  Fly    48 PLIIMDWHRWANRSDQDVYDYKIKEDEFEGKGIPYNDWTLRLTVAIERSHCETFIAFQEQIPEFA 112
            ||:.....||               :..|.|..|..|..:|.|.|:      |:.|.|.....|.
Zfish   263 PLVAKFDQRW---------------EALEEKEYPGADSRIRYTSAL------TYDAVQVMTEAFR 306

  Fly   113 RYFYHASIYSIWRSLRNRFMFV-----------YTKEFEDKKDSYLSGYIFQDQPNILVITSQYL 166
              |.|.....|.|...|.....           ..:..:..:...|:|.|..||
Zfish   307 --FLHKQRIDISRRGNNGDCLANPAVPWAQGVEIERALKQVRVDGLTGNIQFDQ----------- 358

  Fly   167 NSSTFEIKTNRFVGPRNFNKNPEPVEFYILQRFDAKG-TKATWETQSAMSSKMRNLKGREVVIGI 230
                :..:.|..|..... ||..||:.......|... ||:.......|     .::.:.|::..
Zfish   359 ----YGRRVNYTVNVMEL-KNSGPVKIGYWNEMDKMAVTKSDLFPNDTM-----GMENKTVIVTT 413

  Fly   231 FDYKPFMLL--------DYEKPPLYYDRFMNTTDVTID-----GTDIQLMLIFCELYNCTIQVDT 282
            ....|:::|        |.|:    |:.:  ..|:..:     |...||.::....|...    .
Zfish   414 ILEAPYVMLKKNAELFTDNER----YEGY--CVDLAAEIAKHCGFKYQLRIVADGKYGAR----D 468

  Fly   283 SEPYDWGDIYLNASGYGLVGMILDRRNDYGVGGMYLWYEAYEYMDMTHFLGRSGVTCLVPAPNR- 346
            :|...|.         |:||.::..:.|..|..:.:.....|.:|.:......|::.::..|.:
Zfish   469 AETKIWN---------GMVGELVYGKADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKS 524

  Fly   347 ---LISWTLLLRPFQFVLWMCVMLCLLLESLALGITRR-----W---EHSSVAAGNSWISSLRFG 400
               :.|:   |.|..:.:|||::...:..|:.|.:..|     |   |......|.| .|:..||
Zfish   525 KPGVFSF---LDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGQLGPS-ESTNEFG 585

  Fly   401 CIS----TLKLFVNQSTNYVTSSYALRTVLVASYMIDIILTTVYSGGLAAILTLPTLEEAADSRQ 461
            ..:    :|..|:.|..:....|.:.|.|....:...:|:.:.|:..|||.||:..:....:|.:
Zfish   586 IFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAE 650

  Fly   462 RLFDHKLIWTGTSQAWITTIDERSADPVLLGLMEHY------RVYDANLISAFSHTE----QMGF 516
            .|.....|..||..|..|....|.:...|...|..|      .|:..|.:.......    :..:
Zfish   651 DLAKQTEIAYGTLDAGSTKEFFRRSKIALFDKMWQYMKSAEPSVFVKNTVEGVLRVRKSKGKYAY 715

  Fly   517 VVERLQFGHLGNTELIEN----DALKRLKLMVDDIYFAFTVAFVPRLWPHLNAYNDFILAWHSSG 577
            ::|...      .|.||.    |.:|....:....|...|    |:.....||.|..:|..:..|
Zfish   716 LLESTM------NEYIEQRKPCDTMKVGGNLDSKGYGIAT----PKGSALRNAVNLAVLKLNEQG 770

  Fly   578 -FDKF---WEWKIAAEYMNAHRQNRIVASEKTNLDIGPVKLGIDNFIGLILLWCFGMICSLLTFL 638
             .||.   | |....|..:...:::    |||:      .|.:.|..|:..:...|:..::|..|
Zfish   771 LLDKLKNKW-WYDKGECGSGGGESK----EKTS------ALSLSNVAGVFYILVGGLGLAMLVAL 824

  Fly   639 GE 640
            .|
Zfish   825 VE 826

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76a	NP_001097647.3	None
gria2a	XP_005170953.1	Periplasmic_Binding_Protein_Type_1	23..391	CDD:299141	32/166 (19%)
		ANF_receptor	51..373	CDD:279440	27/148 (18%)
		PBP2_iGluR_AMPA	406..783	CDD:270433	82/410 (20%)
		Lig_chan	538..816	CDD:278489	64/299 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591736
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840