Protein Alignment Ir76a and Grin2c

DIOPT Version :9

• Sequence 1: NP_001097647.3
• Gene: Ir76a / 40157
• FlyBaseID: FBgn0260874
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: XP_017169765.1
• Gene: Grin2c / 14813
• MGIID: 95822
• Length: 1307
• Species: Mus musculus
• Alignment Length: 629
• Identity: 118/629 - (18%)
• Similarity: 213/629 - (33%)
• Gaps: 211/629 - (33%)

  Fly   115 FYHASIYSIWRSLRNRFMFVYTKEFEDKKDSYLSGYIFQDQPNILVITSQYLNSSTFEIKTNRF- 178
            ||...:...|..          ::|......||.      ||.::||.   ||.........|:
Mouse   393 FYRHLLNVTWEG----------RDFSFSPGGYLV------QPTMVVIA---LNRHRLWEMVGRWD 438

  Fly   179 ---------VGPRNFNKNPEPVEFYILQRFDAKGTKATWETQSAMSSKMRNLKGREVVIGIFDYK 234
                     |.|| ::.:.:||                             :..|.:.:...:.:
Mouse   439 HGVLYMKYPVWPR-YSTSLQPV-----------------------------VDSRHLTVATLEER 473

  Fly   235 PFMLLDYEKP------PLYYDRFMNT------TDVTIDGTDI-QLMLIFCELYNCTIQVDTSEPY 286
            ||::::...|      |       ||      ::.|....|| ....:.|:.:...|....::..
Mouse   474 PFVIVESPDPGTGGCVP-------NTVPCRRQSNHTFSSGDITPYTKLCCKGFCIDILKKLAKVV 531

  Fly   287 DWG-DIYLNASG----------YGLVGMILDRRNDYGVGGMYLWYEAYEYMDMTHFLGRSGVTCL 340
            .:. |:||..:|          .|::|.:..:|.|..:|.:.:..|..|.:|.:.....:|::.:
Mouse   532 KFSYDLYLVTNGKHGKRVRGVWNGMIGEVYYKRADMAIGSLTINEERSEIIDFSVPFVETGISVM 596

  Fly   341 VPAPNRLISWTLLLRPFQFVLW-MCVMLCLLLESLALGITRRWEHSSVAAGNSWIS--------S 396
            |...|..:|.:..|.|:...:| |..::||.:.::.:.:   :|:.|..:.|..::        |
Mouse   597 VARSNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAITVFM---FEYFSPVSYNQNLTKGKKSGGPS 658

  Fly   397 LRFGCISTLKLFVNQSTNYV-------TSSYALRTVLVASYMIDIILTTVYSGGLAAILTLPTLE 454
            ...| .|...|:.....|.|       |:|..:  |||.::...|.|.: |:..|||.:   ..|
Mouse   659 FTIG-KSVWLLWALVFNNSVPIENPRGTTSKIM--VLVWAFFAVIFLAS-YTANLAAFM---IQE 716

  Fly   455 EAADSRQRLFDHKLIWTGTSQAWITTIDERSAD---PVLLGLMEHYRVYDANLISAF--SHTEQM 514
            :..|:...|.|.|.              :|..|   |...|.:.:... :.|:.|.:  .||..:
Mouse   717 QYIDTVSGLSDKKF--------------QRPQDQYPPFRFGTVPNGST-ERNIRSNYRDMHTHMV 766

  Fly   515 GFVVERLQFGHLGNTELIENDALKRLKL-------MVDD-IYFAFTVAFVPRLWPHLNAYND--- 568
            .|           |...:| |||..||:       .:|. ||.|..:.::        |..|
Mouse   767 KF-----------NQRSVE-DALTSLKMGARHVSRKLDAFIYDAAVLNYM--------AGKDEGC 811

  Fly   569 ----------FILAWHSSGFDKFWEWKIAAE------------------YMNA---HRQNRIVAS 602
                      |....:.....|...||.|.:                  :::.   :.:|.:::|
Mouse   812 KLVTIGSGKVFATTGYGIAMQKDSHWKRAIDLALLQFLGDGETQKLETVWLSGICHNEKNEVMSS 876

  Fly   603 EKTNLDIGPVKLGIDNFIGLILLWCFGMICSLLTFLGE---LWR 643
                      ||.|||..|:..:....|..:||.|..|   .|:
Mouse   877 ----------KLDIDNMAGVFYMLLVAMGLALLVFAWEHLVYWK 910

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76a	NP_001097647.3	None
Grin2c	XP_017169765.1	PBP1_iGluR_NMDA_NR2	90..446	CDD:380601	13/71 (18%)
		PBP2_iGluR_NMDA_Nr2	462..868	CDD:270436	86/457 (19%)
		NMDAR2_C	905..>980	CDD:371139	1/6 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846620
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930